When power calculations won’t do: Fermi approximation of animal numbers
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In such cases, power calculations are not appropriate and sample sizes can be estimated based on operational capacity and constraints.
“In such cases, power calculations are not appropriate and sample sizes can be estimated based on operational capacity and constraints [44].”
From Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 (2020) · cites this paper as [44]
Cites
How we design feasibility studies
Bowen, D. J., Kreuter, M., Spring, B., Cofta-Woerpel, L., Linnan, L., Weiner, D., Bakken, S., Kaplan, C. P., Squiers, L., Fabrizio, C., et al. (2009) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2009.02.002 · Cited by 3,922 · see citing works
Design and analysis of pilot studies: recommendations for good practice
Lancaster, G. A., Dodd, S., & Williamson, P. R. (2004) · Journal of Evaluation in Clinical Practice · doi:10.1111/j..2002.384.doc.x · Cited by 2,572 · see citing works
Whitehead, A. L., Julious, S. A., Cooper, C. L., & Campbell, M. J. (2016) · Statistical Methods in Medical Research · doi:10.1177/0962280215588241 · Cited by 1,936 · see citing works
Eldridge, S. M., Lancaster, G. A., Campbell, M. J., Thabane, L., Hopewell, S., Coleman, C. L., & Bond, C. M. (2016) · PLOS ONE · doi:10.1371/journal.pone.0150205 · Cited by 1,581 · see citing works
A call for transparent reporting to optimize the predictive value of preclinical research
Landis, S. C., Amara, S. G., Asadullah, K., Austin, C. P., Blumenstein, R., Bradley, E. W., Crystal, R. G., Darnell, R. B., Ferrante, R. J., Fillit, H., et al. (2012) · Nature · doi:10.1038/nature11556 · Cited by 1,196 · see citing works
Distinguishing between exploratory and confirmatory preclinical research will improve translation
Kimmelman, J., Mogil, J. S., & Dirnagl, U. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001863 · Cited by 236 · see citing works
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Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
Percie du Sert, N., Ahluwalia, A., Alam, S., Avey, M. T., Baker, M., Browne, W. J., Clark, A., Cuthill, I. C., Dirnagl, U., Emerson, M., et al. (2020) · PLOS Biology · doi:10.1371/journal.pbio.3000411 · Cited by 2,677 · see citing works
Self-citation
- Authors
- Reynolds, P. S.
- Affiliations
- University of Florida Health (US)
- Corresponding author
- Reynolds, Penny S.
- ORCID
- Reynolds, Penny S.
- Venue
- Lab Animal
- Published
- 2019-08-21
- Volume
- 48
- Issue
- 9
- Pages
- 249-253
- ISSN
- 0093-7355 (ISSN-L)
- 1548-4475
- OpenAlex
- W2969622677
- Cited by
- 21
- References
- 6
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 2 · 2022: 5 · 2021: 5 · 2020: 2
- FWCI
- 3.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Lab Animal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Florida
- Topics
- Health Sciences › Veterinary › Small Animals › Animal testing and alternatives
- Physical Sciences › Mathematics › Statistics and Probability › Census and Population Estimation
- Health Sciences › Veterinary › Small Animals › Animal Behavior and Welfare Studies
- Keywords
- animal numbers, power analysis, animal welfare, sample size determination, animal experimentation
- MeSH terms
- Animals, Animal Welfare, Animals, Laboratory, Laboratory Animal Science, Models, Theoretical, Population Density
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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