The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Galectin-1 as a potential cancer target
Open accessAbstract
Galectins are a family of structurally related carbohydrate-binding proteins, which are defined by their affinity for poly-N-acetyllactosamine-enriched glycoconjugates and sequence similarities in the carbohydrate recognition domain. Galectin-1, a member of this family, contributes to different events associated with cancer biology, including tumour transformation, cell cycle regulation, apoptosis, cell adhesion, migration and inflammation. In addition, recent evidence indicates that galectin-1 contributes to tumour evasion of immune responses. Given the increased interest of tumour biologists and clinical oncologists in this field and the potential use of galectins as novel targets for anticancer drugs, we summarise here recent advances about the role of galectin-1 in different events of tumour growth and metastasis.
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Matarrese, P., Tinari, A., Mormone, E., Bianco, G. A., Toscano, M. A., Ascione, B., Rabinovich, G. A., & Malorni, W. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m409752200 · Cited by 182
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Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands
Cecioni, S., Imberty, A., & Vidal, S. (2015) · Chemical Reviews · doi:10.1021/cr500303t · Cited by 544
Metadata
- Authors
- Rabinovich, G. A.
- Venue
- British Journal of Cancer
- Published
- 2005-03-22
- Volume
- 92
- Issue
- 7
- Pages
- 1188-1192
- ISSN
- 0007-0920 (ISSN-L)
- 1532-1827
- OpenAlex
- W2001413622
- Cited by
- 240
- References
- 1
- FWCI
- 3.54
- Type
- journal article
- Language
- en
- Open access
- hybrid
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