Why do patients with erectile dysfunction abandon effective therapy with sildenafil (Viagra)?
Abstract
This prospective study determined the rate of abandonment of sildenafil therapy and assessed the reasons for abandonment. Between January 2001 and December 2002, 234 patients with erectile dysfunction (ED) at three independent centers successfully began therapy with sildenafil 50 or 100 mg. The rate of noncompliance was 31%. A telephone survey of these patients was conducted to determine the reasons for abandonment. The majority reported that they had had no opportunity or desire for sexual intercourse or that their partners had shown no sexual interest. Few patients stated that the high cost of the medication or that adverse events were the cause.
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Long-term adherence to medical treatment for ED is poor and erectile function recovery is not always achieved.
“Although medical treatments have been shown to be physiologically effective, long-term adherence to medical treatment is poor and erectile function recovery is not always achieved, often depending on how well men are instructed about (correct) use of the medical aids.99, 100, 101”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [101]
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References 8 · Cited by 81
- Authors
- Klotz, T., Mathers, M., Klotz, R., & Sommer, F.
- Affiliations
- Klinikum Weiden (DE)
- München Klinik (DE)
- University of Cologne (DE)
- Corresponding author
- Klotz, T
- ORCID
- Sommer, F
- Venue
- International Journal of Impotence Research
- Published
- 2004-06-17
- Volume
- 17
- Issue
- 1
- Pages
- 2-4
- ISSN
- 0955-9930 (ISSN-L)
- 1476-5489
- OpenAlex
- W2038929974
- Cited by
- 81
- References
- 8
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2021: 2 · 2020: 4 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 7 · 2015: 3 · 2014: 6 · 2013: 7 · 2012: 4
- FWCI
- 4.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Impotence Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Keywords
- erectile dysfunction, sildenafil, treatment discontinuation, medication non-adherence, reasons for discontinuation, sexual desire, drug costs, adverse events
- MeSH terms
- Sildenafil Citrate, Data Collection, Humans, Erectile Dysfunction, Male, Middle Aged, Phosphodiesterase Inhibitors, Piperazines, Prospective Studies, Purines, Sulfones, Telephone, Treatment Refusal, Drug Costs, Treatment Failure
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