Cited by 271Chronic Kidney Disease and DiabetesStatistical Methods in Clinical TrialsEthics in Clinical Research

The DOI matches its Crossref record; 116 of the 117 references it cites were found in a registry or an index.

The exclusion of patients with chronic kidney disease from clinical trials in coronary artery disease

Open access

Charytan, D., Kuntz, R.E.·2006·Kidney International

DOI 10.1038/sj.ki.5001934PMC PMC2950017

Open this paper in CoChat — free account

Abstract

Chronic kidney disease (CKD) is associated with a high risk of death from coronary artery disease and may modify the response to standard cardiovascular therapies. Treatment of subjects with CKD should ideally be based on evidence from randomized, clinical trials, but how often subjects with CKD have been excluded from these trials is uncertain. We undertook this study in order to quantify how often subjects with moderate to advanced CKD were excluded from large cardiovascular trials. MEDLINE and the reference list of selected articles were searched in order to identify large, randomized, controlled trials of five different coronary artery disease therapies published between 1998 and 2005. Exclusion criteria and reported clinical characteristics of subjects were abstracted. Rates of exclusion and reporting of baseline characteristics of study participants were compared for CKD, diabetes, history of smoking, and hypertension. Eighty-six trials randomizing 411 653 patients were identified. More than 80% of trials excluded subjects with end-stage renal disease and 75.0% excluded patients with CKD. Subjects with diabetes, hypertension, or a history of smoking were excluded less than 4% of the time. Baseline renal function of study participant was reported in only 7% of trials. Patients with CKD are frequently excluded from coronary artery disease trials and renal function of randomized subjects is rarely reported. These findings reinforce the notion that available data on the tre…

Integrity signals

Registry

Crossref · 10.1038/sj.ki.5001934

Cites

116 of 116 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
Go, A. S., Chertow, G. M., Fan, D., McCulloch, C. E., & Hsu, C.-Y. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa041031 · Cited by 11,369
Prediction of coronary heart disease using risk factor categories
Wilson, P. W. F., D’Agostino, R. B., Levy, D., Belanger, A. M., Silbershatz, H., & Kannel, W. B. (1998) · Circulation · doi:10.1161/01.cir.97.18.1837 · Cited by 9,581
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial
(2002) · The Lancet · doi:10.1016/s0140-6736(02)09327-3 · Cited by 6,992
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
(2001) · New England Journal of Medicine · doi:10.1056/nejmoa010746 · Cited by 6,470
Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the hypertension optimal treatment (HOT) randomised trial
Hansson, L., Zanchetti, A., Carruthers, S. G., Dahlöf, B., Elmfeldt, D., Julius, S., Ménard, J., Rahn, K. H., Wedel, H., & Westerling, S. (1998) · The Lancet · doi:10.1016/s0140-6736(98)04311-6 · Cited by 5,728
Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
Dahlöf, B., Devereux, R. B., Kjeldsen, S. E., Julius, S., Beevers, G., de Faire, U., Fyhrquist, F., Ibsen, H., Kristiansson, K., Lederballe-Pedersen, O., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08089-3 · Cited by 5,407
Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels
(1998) · New England Journal of Medicine · doi:10.1056/nejm199811053391902 · Cited by 5,261
Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels: Results of AFCAPS/TexCAPS
Downs, J. R., Clearfield, M., Weis, S., Whitney, E., Shapiro, D. R., Beere, P. A., Langendorfer, A., Stein, E. A., Kruyer, W., Gotto, Jr., et al. (1998) · JAMA · doi:10.1001/jama.279.20.1615 · Cited by 5,236
Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes
Cannon, C. P., Braunwald, E., McCabe, C. H., Rader, D. J., Rouleau, J. L., Belder, R., Joyal, S. V., Hill, K. A., Pfeffer, M. A., & Skene, A. M. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040583 · Cited by 4,938
Sirolimus-Eluting Stents versus Standard Stents in Patients with Stenosis in a Native Coronary Artery
Moses, J. W., Leon, M. B., Popma, J. J., Fitzgerald, P. J., Holmes, D. R., O’Shaughnessy, C. D., Caputo, R. P., Kereiakes, D. J., Williams, D. O., Teirstein, P. S., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa035071 · Cited by 4,222
Self-citation

Show all 117 references

Research works printed but not linked: 1

Gilbertson, 2003, Projecting the US ESRD population to 2030, J Am Soc Nephrol, 14, F-PO881

Sorted by citations

Chronic kidney disease
Webster, A. C., Nagler, E. V., Morton, R. L., & Masson, P. (2017) · The Lancet · doi:10.1016/s0140-6736(16)32064-5 · Cited by 3,842
Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO)
Herzog, C. A., ASINGER, R. W., Berger, A. K., Charytan, D. M., Dı́ez, J., Hart, R. G., Eckardt, K., Kasiske, B. L., McCullough, P. A., PASSMAN, R. S., et al. (2011) · Kidney International · doi:10.1038/ki.2011.223 · Cited by 934
Self-citation
Management of coronary disease in patients with advanced kidney disease
Bangalore, S., Maron, D. J., O’Brien, S. M., Fleg, J. L., Kretov, E. I., Briguori, C., Kaul, U., Reynolds, H. R., Mazurek, T., Sidhu, M. S., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa1915925 · Cited by 499
Cardiorenal Syndrome Revisited
Zannad, F. M., & Rossignol, P. (2018) · Circulation · doi:10.1161/circulationaha.117.028814 · Cited by 351
Chronic kidney disease and arrhythmias: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Turakhia, M. P., Blankestijn, P. J., Carrero, J. J., Clase, C. M., Deo, R., Herzog, C. A., Kasner, S. E., PASSMAN, R. S., Pecoits‐Filho, R., Reinecke, H., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy060 · Cited by 297
Self-citation
Disorders of Hemostasis Associated with Chronic Kidney Disease
Jalal, D. I., Chonchol, M., & Targher, G. (2010) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0030-1248722 · Cited by 232
Chronic kidney disease in patients with cardiac rhythm disturbances or implantable electrical devices: clinical significance and implications for decision making-a position paper of the European Heart Rhythm Association endorsed by the Heart Rhythm Society and the Asia Pacific Heart Rhythm Society
Boriani, G., Savelieva, I., Dan, G., Deharo, J., Ferro, C. J., Israel, C. W., Lane, D. A., Manna, G. L., Morton, J. B., Moya‐Mitjans, À., et al. (2015) · EP Europace · doi:10.1093/europace/euv202 · Cited by 187
Effects of Beta-Adrenergic Antagonists in Patients With Chronic Kidney Disease
Badve, S. V., Roberts, M. A., Hawley, C. M., Cass, A., Garg, A. X., Krum, H., Tonkin, A. M., & Perkovic, V. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.04.041 · Cited by 177
Lipid-Lowering Therapy in Persons With Chronic Kidney Disease
Upadhyay, A., Earley, A., Lamont, J. L., Haynes, S. M., Wanner, C., & Balk, E. M. (2012) · Annals of Internal Medicine · doi:10.7326/0003-4819-157-4-201208210-00005 · Cited by 166
Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study
Schmidt, M., Mansfield, K. E., Bhaskaran, K., Nitsch, D., Sørensen, H. T., Smeeth, L., & Tomlinson, L. A. (2017) · BMJ · doi:10.1136/bmj.j791 · Cited by 157
Representation of Patients With Kidney Disease in Trials of Cardiovascular Interventions
Konstantinidis, I., Nadkarni, G. N., Yacoub, R., Saha, A., Simoes, P. K., Parikh, C. R., & Coca, S. G. (2015) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2015.6102 · Cited by 149
Revascularization in Patients With Multivessel Coronary Artery Disease and Chronic Kidney Disease
Bangalore, S., Guo, Y., Samadashvili, Z., Blecker, S., Xu, J., & Hannan, E. L. (2015) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2015.06.1334 · Cited by 141
Secular Trends in Cardiovascular Mortality Rates of Patients Receiving Dialysis Compared With the General Population
Roberts, M. A., Polkinghorne, K. R., McDonald, S. P., & Ierino, F. L. (2011) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2011.01.024 · Cited by 141
CKD and Sudden Cardiac Death
Whitman, I. R., Feldman, H. I., & Deo, R. (2012) · Journal of the American Society of Nephrology · doi:10.1681/asn.2012010037 · Cited by 132
Early Angiography in Patients with Chronic Kidney Disease
Charytan, D. M., Wallentin, L. C., Lagerqvist, B., Spacek, R., de Winter, R. J., Stern, N. M., Braunwald, E., Cannon, C. P., & Choudhry, N. K. (2009) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.05551008 · Cited by 120
Self-citation
Focused Atorvastatin Therapy in Managed-Care Patients With Coronary Heart Disease and CKD
Koren, M. J., Davidson, M. H., Wilson, D. J., Fayyad, R. S., Zuckerman, A., & Reed, D. P. (2009) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2008.11.025 · Cited by 115
Epidemiology of Chronic Kidney Disease in Heart Failure
Ahmed, A., & Campbell, R. C. (2008) · Heart Failure Clinics · doi:10.1016/j.hfc.2008.03.008 · Cited by 115
Optimal Medical Therapy With or Without Percutaneous Coronary Intervention for Patients With Stable Coronary Artery Disease and Chronic Kidney Disease
Sedlis, S. P., Jurkovitz, C. T., Hartigan, P. M., Goldfarb, D. S., Lorin, J. D., Dada, M. R., Maron, D. J., Spertus, J. A., Mancini, G. B. J., Teo, K. K., et al. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.07.043 · Cited by 115
The risk of atherosclerosis in patients with chronic kidney disease
Olechnowicz-Tietz, S., Gluba, A., Paradowska, A., Banach, M., & Rysz, J. (2013) · International Urology and Nephrology · doi:10.1007/s11255-013-0407-1 · Cited by 105
Predictive Value of Myocardial Perfusion Single-Photon Emission Computed Tomography and the Impact of Renal Function on Cardiac Death
Hakeem, A., Bhatti, S., Dillie, K. S., Cook, J. R., Samad, Z. Z., Roth-Cline, M. D., & Chang, S. M. (2008) · Circulation · doi:10.1161/circulationaha.108.788109 · Cited by 103
Tissue-engineered kidney disease models
DesRochers, T. M., Palma, E., & Kaplan, D. L. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.12.002 · Cited by 100
GRADE equity guidelines 3: considering health equity in GRADE guideline development: rating the certainty of synthesized evidence
Welch, V. A., Akl, E. A., Pottie, K., Ansari, M. T., Briel, M., Christensen, R., Dans, A., Dans, L., Eslava-Schmalbach, J., Guyatt, G., et al. (2017) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2017.01.015 · Cited by 88
The Growing Challenge of Chronic Kidney Disease: An Overview of Current Knowledge
Borg, R., Carlson, N., Søndergaard, J., & Persson, F. (2023) · International Journal of Nephrology · doi:10.1155/2023/9609266 · Cited by 115
Health status after invasive or conservative care in coronary and advanced kidney disease
Spertus, J. A., Jones, P. G., Maron, D. J., Mark, D. B., O’Brien, S. M., Fleg, J. L., Reynolds, H. R., Stone, G. W., Sidhu, M. S., Chaitman, B. R., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa1916374 · Cited by 84
Pharmacotherapy in Chronic Kidney Disease Patients Presenting With Acute Coronary Syndrome
Washam, J. B., Herzog, C. A., Beitelshees, A. L., Cohen, M. G., Henry, T. D., Kapur, N. K., Mega, J. L., Menon, V., Page, R. L., II, & Newby, L. K. (2015) · Circulation · doi:10.1161/cir.0000000000000183 · Cited by 85
Atrial Fibrillation in CKD: Balancing the Risks and Benefits of Anticoagulation
Ng, K. P., Edwards, N. C., Lip, G. Y. H., Townend, J., & Ferro, C. J. (2013) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2013.02.381 · Cited by 82
Benefits of Icosapent Ethyl Across the Range of Kidney Function in Patients With Established Cardiovascular Disease or Diabetes: REDUCE-IT RENAL
Majithia, A., Bhatt, D. L., Friedman, A. N., Miller, M., Steg, P. G., Brinton, E. A., Jacobson, T. A., Ketchum, S. B., Juliano, R. A., Jiao, L., et al. (2021) · Circulation · doi:10.1161/circulationaha.121.055560 · Cited by 74
P2Y 12 -ADP Receptor Blockade in Chronic Kidney Disease Patients With Acute Coronary Syndromes
Bonello, L., Angiolillo, D. J., Aradi, D., & Sibbing, D. (2018) · Circulation · doi:10.1161/circulationaha.118.032078 · Cited by 74
Association of NT-proBNP and BNP With Future Clinical Outcomes in Patients With ESKD: A Systematic Review and Meta-analysis
Harrison, T. G., Shukalek, C. B., Hemmelgarn, B. R., Zarnke, K. B., Ronksley, P. E., Iragorri, N., Graham, M. M., & James, M. T. (2020) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2019.12.017 · Cited by 72
Cardiovascular risk and management in chronic kidney disease
Rucker, D., & Tonelli, M. A. (2009) · Nature Reviews Nephrology · doi:10.1038/nrneph.2009.42 · Cited by 67
Representation of Patients With Chronic Kidney Disease in Clinical Trials of Cardiovascular Disease Medications
Colombijn, J. M. T., Idema, D. L., van Beem, S., Blokland, A. M., van der Braak, K., Handoko, M. L., Veld, L. F. H. I. ’., Kaul, T., Kolagasigil-Akdemir, N., Kusters, M. P. T., et al. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.0427 · Cited by 68
Aspirin for Primary Prevention of Cardiovascular Disease and Renal Disease Progression in Chronic Kidney Disease Patients: a Multicenter Randomized Clinical Trial (AASER Study)
Goicoechea, M., de Vinuesa, S. G., Quiroga, B., Verde, E., Bernis, C., Morales, E., Juarez, G. M. F., de Sequera, P., Verdalles, Ú., Delgado, R., et al. (2018) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-018-6802-1 · Cited by 60
International Study of Comparative Health Effectiveness with Medical and Invasive Approaches–Chronic Kidney Disease (ISCHEMIA-CKD): Rationale and design
Bangalore, S., Maron, D. J., Fleg, J. L., O’Brien, S. M., Herzog, C. A., Stone, G. W., Mark, D. B., Spertus, J. A., Alexander, K. P., Sidhu, M. S., et al. (2018) · American Heart Journal · doi:10.1016/j.ahj.2018.07.023 · Cited by 63
Ischemic Conditioning Protects the Uremic Heart in a Rodent Model of Myocardial Infarction
Byrne, C. J., McCafferty, K., Kieswich, J. E., Harwood, S., Andrikopoulos, P., Raftery, M., Thiemermann, C., & Yaqoob, M. (2012) · Circulation · doi:10.1161/circulationaha.111.055392 · Cited by 57
Efficacy and Safety of Direct Oral Anticoagulants vs Warfarin in Patients with Chronic Kidney Disease and Dialysis Patients: A Systematic Review and Meta-Analysis
Chen, H.-Y., Ou, S., Huang, C., Lee, P., Chou, K.-J., Lin, P., & Su, Y. (2021) · Clinical Drug Investigation · doi:10.1007/s40261-021-01016-7 · Cited by 56
Persistent Underrepresentation of Kidney Disease in Randomized, Controlled Trials of Cardiovascular Disease in the Contemporary Era
Maini, R., Wong, D. B., Addison, D., Chiang, E., Weisbord, S. D., & Jneid, H. M. (2018) · Journal of the American Society of Nephrology · doi:10.1681/asn.2018070674 · Cited by 54
P2Y12 inhibitors in acute coronary syndrome patients with renal dysfunction: an analysis from the RENAMI and BleeMACS projects
FILIPPO, O. D., D’Ascenzo, F., Raposeiras‐Roubín, S., Abu‐Assi, E., Peyracchia, M., Bocchino, P. P., Kinnaird, T. D., Ariza‐Solé, A., Liebetrau, C., Manzano‐Fernández, S., et al. (2019) · European Heart Journal - Cardiovascular Pharmacotherapy · doi:10.1093/ehjcvp/pvz048 · Cited by 53
Clinical Outcomes of Treatment by Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graft Surgery in Patients With Chronic Kidney Disease Undergoing Index Revascularization in Ontario
Chan, W., Ivanov, J., Ko, D. T., Fremes, S., Rao, V., Jolly, S., Cantor, W., Lavi, S., Overgaard, C., Ruel, M., et al. (2014) · Circulation. Cardiovascular Interventions · doi:10.1161/circinterventions.114.001973 · Cited by 51
Safety and Efficacy of Antiplatelet and Antithrombotic Therapy in Acute Coronary Syndrome Patients With Chronic Kidney Disease
Basra, S. S., Tsai, P. I.-H., & Lakkis, N. M. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.08.051 · Cited by 51
Chronic kidney disease and arrhythmias: highlights from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Wanner, C., Herzog, C. A., Turakhia, M. P., Blankestijn, P. J., Carrero, J. J., Clase, C. M., Deo, R., Kasner, S. E., PASSMAN, R. S., Pecoits‐Filho, R., et al. (2018) · Kidney International · doi:10.1016/j.kint.2018.05.005 · Cited by 51
Identifying critically important vascular access outcomes for trials in haemodialysis: an international survey with patients, caregivers and health professionals
Viecelli, A. K., Howell, M., Tong, A., Teixeira-Pinto, A. M., O’Lone, E., Ju, A., Craig, J. C., Hooi, L. S., Lee, T. C., Lok, C. E., et al. (2019) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfz148 · Cited by 50
Chronic Kidney Disease and the Public Health
Himmelfarb, J. (2007) · JAMA · doi:10.1001/jama.297.23.2630 · Cited by 49
Low-Dose Aspirin for Prevention of Cardiovascular Disease in Patients with Chronic Kidney Disease
Kim, A. J., Lim, H. J., Ro, H., Ko, K., Han, S. Y., Chang, J. H., Lee, H. H., Chung, W., & Jung, J. Y. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104179 · Cited by 46
Associations of Kidney Function with Cardiovascular Medication Use after Myocardial Infarction
Winkelmayer, W. C., Levin, R., & Setoguchi, S. (2008) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.02010408 · Cited by 45
Cardiovascular Outcome Trials in Patients With Advanced Kidney Disease
Zannad, F. M., & Rossignol, P. (2017) · Circulation · doi:10.1161/circulationaha.117.027338 · Cited by 45
Development of an Adverse Drug Reaction Risk Assessment Score among Hospitalized Patients with Chronic Kidney Disease
Sharif‐Askari, F. S., Sulaiman, S. A. S., Sharif‐Askari, N. S., & Hussain, A. A. S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095991 · Cited by 46
Sex-Based Differences in Risk Factors and Complications of Chronic Kidney Disease
Wyld, M. L. R., Mata, N. L. D. L., Viecelli, A. K., Swaminathan, R., O’Sullivan, K. M., O’Lone, E., Rowlandson, M., Francis, A., Wyburn, K., & Webster, A. C. (2022) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2022.04.006 · Cited by 44
Clinical presentation of myocardial infarction contributes to lower use of coronary angiography in patients with chronic kidney disease
Charytan, D. M., Setoguchi, S., Solomon, D. H., Avorn, J., & Winkelmayer, W. C. (2007) · Kidney International · doi:10.1038/sj.ki.5002159 · Cited by 40
Self-citation
Detection and management of nephrotoxicity during drug development
Loghman-Adham, D. M., Weber, C. I. K., Ciorciaro, C., Mann, D. J., & Meier, M. (2012) · Expert Opinion on Drug Safety · doi:10.1517/14740338.2012.691964 · Cited by 40
Using Real‐World Data to Extrapolate Evidence From Randomized Controlled Trials
Wang, S. V., Schneeweiß, S., Gagne, J. J., Evers, T., Gerlinger, C., Desai, R. J., & Najafzadeh, M. (2018) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.1210 · Cited by 40
Intersection Between Chronic Kidney Disease and Cardiovascular Disease
Laffin, L. J., & Bakris, G. L. (2021) · Current Cardiology Reports · doi:10.1007/s11886-021-01546-8 · Cited by 44
Cardiovascular Complications in Diabetic Kidney Disease
Patel, T. V., & Charytan, D. M. (2010) · Seminars in Dialysis · doi:10.1111/j.1525-139x.2009.00704.x · Cited by 37
Self-citation
Children of a lesser god: exclusion of chronic kidney disease patients from clinical trials
Zoccali, C., Blankestijn, P. J., Bruchfeld, A. N., Capasso, G., Fliser, D., Fouque, D. P., Goumenos, D. S., Ketteler, M., Massy, Z. A., Rychlík, I., et al. (2019) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfz023 · Cited by 37
Burden and challenges of heart failure in patients with chronic kidney disease. A call to action
Romero-González, G. A., Ravassa, S., González, O., Lorenzo, I., Rojas, M. A., García-Trigo, I., Garcı́a-Fernández, N., Lavilla, J., Martín-Moreno, P. L., López, B., et al. (2019) · Nefrología · doi:10.1016/j.nefro.2019.10.005 · Cited by 37
The influence of cognitive-behavioral therapy on depression in dialysis patients – meta-analysis
Zegarow, P., Mańczak, M., Rysz, J., & Olszewski, R. (2020) · Archives of Medical Science · doi:10.5114/aoms.2019.88019 · Cited by 36
A Review of the Costs and Cost Effectiveness of Interventions in Chronic Kidney Disease
Menzin, J., Lines, L. M., Weiner, D. E., Neumann, P. J., Nichols, C. I., Rodriguez, L., Agodoa, I., & Mayne, T. J. (2011) · PharmacoEconomics · doi:10.2165/11588390-000000000-00000 · Cited by 37
Impact of Chronic Kidney Disease on Postinfarction Inflammation, Oxidative Stress, and Left Ventricular Remodeling
Naito, K., Anzai, T., Yoshikawa, T., Anzai, A., Kaneko, H., Kohno, T., Takahashi, T., Kawamura, A., & Ogawa, S. (2008) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2008.07.233 · Cited by 36
Association of the Systemic Immune-Inflammation Index with Outcomes in Acute Coronary Syndrome Patients with Chronic Kidney Disease
Shi, S., Kong, S., Ni, W., Lu, Y., Li, J., Huang, Y., Chen, J., Lin, K., Li, Y., Ke, J., et al. (2023) · Journal of Inflammation Research · doi:10.2147/jir.s397615 · Cited by 35
Less use of standard guideline-based treatment of myocardial infarction in patients with chronic kidney disease: a Danish nation-wide cohort study
Blicher, T. M., Hommel, K., Olesen, J. B., Torp-Pedersen, C. T., Madsen, M., & Kamper, A. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht220 · Cited by 34
Cardiovascular Disease in Patients with Chronic Kidney Disease
Weiner, D. E., & Sarnak, M. J. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4377-0987-2.00010-8 · Cited by 35
Cardiovascular disease in chronic kidney disease
Saran, A. M., & DuBose, T. D. (2008) · Therapeutic Advances in Cardiovascular Disease · doi:10.1177/1753944708096379 · Cited by 33
Cardiovascular Complications of Chronic Kidney Disease: An Introduction
Warrens, H., Banerjee, D., & Herzog, C. A. (2022) · European Cardiology Review · doi:10.15420/ecr.2021.54 · Cited by 40
A critical review of chronic kidney disease as a risk factor for coronary artery disease
Coyle, M., Flaherty, G. T., & Jennings, C. S. (2021) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2021.100822 · Cited by 35
Drug‐eluting stents in patients with end‐stage renal disease: Meta‐analysis and systematic review of the literature
Abdel‐Latif, A., Mukherjee, D., Mesgarzadeh, P., & Ziada, K. M. (2010) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.22562 · Cited by 31
Optimal Treatment Strategies in Patients with Chronic Kidney Disease and Coronary Artery Disease
Volodarskiy, A., Kumar, S., Amin, S., & Bangalore, S. (2016) · The American Journal of Medicine · doi:10.1016/j.amjmed.2016.06.046 · Cited by 31
Intersection of cardiovascular disease and kidney disease
Bansal, N., Hsu, C., & Go, A. S. (2014) · Current Opinion in Nephrology & Hypertension · doi:10.1097/01.mnh.0000444820.80249.56 · Cited by 30
Exclusion of Patients With Kidney Disease From Cardiovascular Trials
Ishida, J. H., & Johansen, K. L. (2015) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2015.6403 · Cited by 29
Prevalence of ambulatory hypotension in elderly patients with CKD stages 3 and 4
Tomlinson, L. A., Holt, S. G., Leslie, A., & Rajkumar, C. (2009) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfp357 · Cited by 29
Association Between Chronic Kidney Disease and Rates of Transfusion and Progression to End‐Stage Renal Disease in Patients Undergoing Transradial Versus Transfemoral Cardiac Catheterization—An Analysis From the Veterans Affairs Clinical Assessment Reporting and Tracking (CART) Program
Vora, A. N., Stanislawski, M. A., Grunwald, G. K., Plomondon, M. E., Rumsfeld, J. S., Maddox, T. M., Vidovich, M. I., Woody, W. W., Nallamothu, B. K., Gurm, H. S., et al. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.116.004819 · Cited by 28
Randomized Controlled Trials in Nephrology: State of the Evidence and Critiquing the Evidence
Samuels, J., & Molony, D. A. (2012) · Advances in Chronic Kidney Disease · doi:10.1053/j.ackd.2012.01.009 · Cited by 29
Outcome of Percutaneous Coronary Intervention During Non–ST‐Segment–Elevation Myocardial Infarction in Elderly Patients With Chronic Kidney Disease
Holzmann, M. J., & Siddiqui, A. J. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.015084 · Cited by 26
Use of Sertraline in Hemodialysis Patients
Kubanek, A., Paul, P., Przybylak, M., Kanclerz, K., Rojek, J. J., Renke, M., Bidzan, L., & Grabowski, J. (2021) · Medicina · doi:10.3390/medicina57090949 · Cited by 28
Improving Cancer Care for Patients With CKD: The Need for Changes in Clinical Trials
Sprangers, B., Perazella, M. A., Lichtman, S. M., Rosner, M. H., & Jhaveri, K. D. (2022) · Kidney International Reports · doi:10.1016/j.ekir.2022.06.005 · Cited by 26
Prevalence, incidence, indication, and choice of antidepressants in patients with and without chronic kidney disease: a matched cohort study in UK Clinical Practice Research Datalink
Iwagami, M., Tomlinson, L. A., Mansfield, K. E., McDonald, H. I., Smeeth, L. L., & Nitsch, D. (2017) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.4212 · Cited by 30
Fixed-Dose Combination Therapy for the Prevention of Cardiovascular Diseases in CKD
Sepanlou, S. G., Mann, J. F. E., Joseph, P. G., Pais, P. S., Gao, P., Sharafkhah, M., Roshandel, G., Yusuf, S., & Malekzadeh, R. (2023) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.0000000000000251 · Cited by 24
Obesity is common in chronic kidney disease and associates with greater antihypertensive usage and proteinuria: evidence from a cross‐sectional study in a tertiary nephrology centre
Martin, W. P., Bauer, J., Coleman, J., Dellatorre‐Teixeira, L., Reeve, J. L., Twomey, P. J., Docherty, N. G., O’Riordan, A., Watson, A. J., le Roux, C. W., et al. (2020) · Clinical Obesity · doi:10.1111/cob.12402 · Cited by 24
Acute coronary syndrome in ESRD patients
Surana, S. P., Riella, L. V., Keithi-Reddy, S. R., Charytan, D. M., & Singh, A. K. (2008) · Kidney International · doi:10.1038/ki.2008.233 · Cited by 23
Self-citation
How do We Manage Coronary Artery Disease in Patients with CKD and ESRD?
Choi, H. Y., Park, H. C., & Ha, S. K. (2014) · Electrolytes & Blood Pressure · doi:10.5049/ebp.2014.12.2.41 · Cited by 23
Research Priorities for Kidney-Related Research—An Agenda to Advance Kidney Care: A Position Statement From the National Kidney Foundation
(2021) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2021.08.018 · Cited by 22
Clopidogrel Use in End‐Stage Kidney Disease
Tanios, B. Y., Itani, H. S., & Zimmerman, D. L. (2014) · Seminars in Dialysis · doi:10.1111/sdi.12338 · Cited by 22
Outcomes of STEMI patients with chronic kidney disease treated with percutaneous coronary intervention: the Malaysian National Cardiovascular Disease Database – Percutaneous Coronary Intervention (NCVD-PCI) registry data from 2007 to 2014
On behalf of NCVD-PCI investigators, Ismail, M. D., Jalalonmuhali, M., Azhari, Z., Mariapun, J., Lee, Z.-V., Abidin, I. Z., Ahmad, W. A. W., & Zuhdi, A. S. M. (2018) · BMC Cardiovascular Disorders · doi:10.1186/s12872-018-0919-9 · Cited by 23
Research in the CKD Clinic: Highs and Lows
Decker, E., & Kendrick, J. (2014) · Advances in Chronic Kidney Disease · doi:10.1053/j.ackd.2014.02.012 · Cited by 21
Location of acute coronary artery thromboses in patients with and without chronic kidney disease
Charytan, D. M., Kuntz, R. E., Garshick, M. S., Candia, S. C., Khan, F., & Mauri, L. (2008) · Kidney International · doi:10.1038/ki.2008.480 · Cited by 21
Self-citation
Sex Differences in Cardiovascular Outcomes in Patients With Kidney Failure
Shah, S., Christianson, A. L., Meganathan, K., Leonard, A. C., Crews, D. C., Rubinstein, J., Mitsnefes, M. M., Schauer, D. P., & Thakar, C. V. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.029691 · Cited by 20
Cause-Specific Mortality in Patients With Advanced Chronic Kidney Disease in the ISCHEMIA-CKD Trial
Sidhu, M. S., Alexander, K. P., Huang, Z., Mathew, R. O., Newman, J. D., O’Brien, S. M., Pellikka, P. A., Lyubarova, R., Bockeria, O. L., Briguori, C., et al. (2023) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2022.10.062 · Cited by 21
Handling polypharmacy –a qualitative study using focus group interviews with older patients, their relatives, and healthcare professionals
Mikkelsen, T. H., Søndergaard, J., Kjær, N. K., Nielsen, J. B., Ryg, J., Kjeldsen, L. J., & Mogensen, C. B. (2023) · BMC Geriatrics · doi:10.1186/s12877-023-04131-6 · Cited by 19
Long-term outcomes of patients with stable coronary disease and chronic kidney dysfunction: 10-year follow-up of the Medicine, Angioplasty, or Surgery Study II Trial
Lima, E. G., Charytan, D. M., Hueb, W. A., de Azevedo, D. F. C., Garzillo, C. L., Favarato, D., Filho, J. P. P. L., Martins, E. B., Batista, D. V., Rezende, P. C., et al. (2018) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfy379 · Cited by 19
Self-citation
Establishing Core Cardiovascular Outcome Measures for Trials in Hemodialysis: Report of an International Consensus Workshop
O’Lone, E., Viecelli, A. K., Craig, J. C., Tong, A., Sautenet, B., Herrington, W. G., Herzog, C. A., Jafar, T. H., Jardine, M., Krane, V., et al. (2020) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2020.01.022 · Cited by 21
Factors Influencing Stent Failure in Chronic Total Occlusion Coronary Intervention
Mahadevan, K., Cosgrove, C., & Strange, J. (2021) · Interventional Cardiology Reviews Research Resources · doi:10.15420/icr.2021.03 · Cited by 18
Medication Issues in Older Individuals With CKD
Rifkin, D. E., & Winkelmayer, W. C. (2010) · Advances in Chronic Kidney Disease · doi:10.1053/j.ackd.2010.03.005 · Cited by 21
Meta-Analysis of Comparison of Drug-Eluting Stents and Bare-Metal Stents in Patients on Dialysis
Li, S., Ye, D., Chen, G., & Xu, W. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2016.12.036 · Cited by 17
Systematic differences in effect estimates between observational studies and randomized control trials in meta-analyses in nephrology
Kimachi, M., Ōnishi, A., Tajika, A., Kimachi, K., & Furukawa, T. A. (2021) · Scientific Reports · doi:10.1038/s41598-021-85519-5 · Cited by 18
Anticoagulation in CKD and ESRD
Leung, K., & MacRae, J. M. (2019) · Journal of Nephrology · doi:10.1007/s40620-019-00592-4 · Cited by 17
Coronary artery disease in dialysis patients: evidence synthesis, controversies and proposed management strategies
the EUDIAL Working Group of ERA-EDTA, Burlacu, A., Genovesi, S., Basile, C., Ortíz, A., Mitra, S., Kirmizis, D. A., Kanbay, M., Davenport, A., SANDE, F. M. V. D., et al. (2020) · Journal of Nephrology · doi:10.1007/s40620-020-00758-5 · Cited by 18
Understanding and Overcoming the Challenges Related to Cardiovascular Trials Involving Patients with Kidney Disease
Ishida, J. H., Chauhan, C., Gillespie, B. S., Gruchalla, K., McCullough, P. A., Quella, S. K., Romero, A., Rossignol, P., Wheeler, D. C., Malley, M. A., et al. (2021) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.17561120 · Cited by 16
Stopping Renin-Angiotensin System Inhibitors in Chronic Kidney Disease: Predictors of Response
Gonçalves, A., Khwaja, A., Ahmed, A. K., Kossi, M. E., & Nahas, M. E. (2011) · Nephron Clinical Practice · doi:10.1159/000330289 · Cited by 16
In-Hospital outcomes in acute coronary syndrome patients with concomitant severe chronic kidney disease undergoing percutaneous coronary intervention
Sattar, S., Ahmed, N., Akhter, Z., Aijaz, S., Lakhani, S., Malik, R., & Pathan, A. Z. (2019) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.35.2.276 · Cited by 16
Comparative Effectiveness of Medical Therapy, Percutaneous Revascularization, and Surgical Coronary Revascularization in Cardiovascular Risk Subgroups of Patients With CKD: A Retrospective Cohort Study of Medicare Beneficiaries
Charytan, D. M., Natwick, T., Solid, C. A., Li, S., Gong, T., & Herzog, C. A. (2019) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2019.04.018 · Cited by 16
Self-citation
Association between baseline LDL-C and prognosis among patients with coronary artery disease and advanced kidney disease
Wang, B., Chen, S., Liu, J., Liang, Y., Meng, L., Yan, X., Huang, H., Chen, G., Huang, Z., Xu, D., et al. (2021) · BMC Nephrology · doi:10.1186/s12882-021-02375-1 · Cited by 14
SIRPα Mediates IGF1 Receptor in Cardiomyopathy Induced by Chronic Kidney Disease
Thomas, S. S., Wu, J., Davogustto, G., Holliday, M. W., Eckel‐Mahan, K. L., Verzola, D., Garibotto, G., Hu, Z., Mitch, W. E., & Taegtmeyer, H. (2022) · Circulation Research · doi:10.1161/circresaha.121.320546 · Cited by 14

Authors: Charytan, D., & Kuntz, R. E.
Affiliations: Brigham and Women's Hospital (US)
Medtronic (United States) (US)
Corresponding author: Charytan, D.
ORCID: Charytan, D.
Venue: Kidney International
Publisher: Elsevier BV
Published: 2006-12
Volume: 70
Issue: 11
Pages: 2021-2030
ISSN: 0085-2538 (ISSN-L)
DOI: 10.1038/sj.ki.5001934
PMC: PMC2950017
OpenAlex: W2030060276
Cited by: 271
References: 117
Citations by year: 2026: 7 · 2025: 10 · 2024: 24 · 2023: 19 · 2022: 17 · 2021: 24 · 2020: 24 · 2019: 13 · 2018: 17 · 2017: 18 · 2016: 11 · 2015: 9 · 2014: 14 · 2013: 10 · 2012: 11
FWCI: 5.59
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 3293 d)
Locations: Kidney International (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (T32 DK007527-22)
Topics: Health Sciences › Medicine › Nephrology › Chronic Kidney Disease and Diabetes
Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
Keywords: chronic kidney disease, coronary artery disease, exclusion criteria, inclusion and exclusion criteria, end-stage renal disease, diabetes mellitus, hypertension, smoking history, cardiovascular disease treatment, generalizability of trial results
MeSH terms: Adrenergic beta-Antagonists, Clinical Trials as Topic, Coronary Artery Disease, Humans, Platelet Aggregation Inhibitors, Patient Selection, Platelet Glycoprotein GPIIb-IIIa Complex, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Renal Insufficiency, Chronic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

The exclusion of patients with chronic kidney disease from clinical trials in coronary artery disease

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks