The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis
Abstract
As discussed in detail in other chapters of this review, chronic hepatitis B (HBV) infection is a major risk factor for hepatocellular carcinoma (HCC). Most HCCs complicate the evolution of an active or inactive cirrhosis. However, some tumors occur on livers with minimal histological changes; the prevalence of such cases varies from one geographical region to the other, being much higher in the southern half of Africa (around 40% of HCCs) than in Asia, America and Europe, where at least 90% of HCCs are associated with the cirrhosis. This heterogeneity is probably a reflection of different environmental and genetic factors. This review will summarize the current knowledge on the mechanisms involved in HBV-related liver carcinogenesis. It will show in particular how viruses can be viewed as tools to discover and dissect new cellular pathways involved in cancer development and emphasize the potential synergistic effects between HBV and hepatitis C virus, as well as between viral infections and other environmental factors, such as alcohol.
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Citations
Cites
Risk of Hepatocellular Carcinoma Across a Biological Gradient of Serum Hepatitis B Virus DNA Level
Chen, C.-J. (2006) · JAMA · doi:10.1001/jama.295.1.65 · Cited by 3,140
HLA-A2.1 restricted peptides from the HBx antigen induce specific CTL responses in vitro and in vivo
Hwang, Y. K., Kim, N. K., Park, J. M., Lee, K.-Y., Han, W.-K., Kim, H.-I., & Cheong, H. S. (2002) · Vaccine · doi:10.1016/s0264-410x(02)00297-9 · Cited by 29
Metadata
- Authors
- Kremsdorf, D., Soussan, P., Paterlini-Brechot, P., & Brechot, C.
- Venue
- Oncogene
- Published
- 2006-06-26
- Volume
- 25
- Issue
- 27
- Pages
- 3823-3833
- ISSN
- 0950-9232 (ISSN-L)
- 1476-5594
- OpenAlex
- W2034992482
- Cited by
- 269
- References
- 2
- FWCI
- 12.17
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis. https://app.cochat.ai/papers/10.1038/sj.onc.1209559
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- Kremsdorf, D., Soussan, P., Paterlini-Brechot, P., & Brechot, C. (2006). Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis. Oncogene. https://doi.org/10.1038/sj.onc.1209559
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
