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Carbon Nanoparticle-based Fluorescent Bioimaging Probes
Open accessAbstract
Fluorescent nanoparticle-based imaging probes have advanced current labelling technology and are expected to generate new medical diagnostic tools based on their superior brightness and photostability compared with conventional molecular probes. Although significant progress has been made in fluorescent semiconductor nanocrystal-based biological labelling and imaging, the presence of heavy metals and the toxicity issues associated with heavy metals have severely limited the application potential of these nanocrystals. Here, we report a fluorescent carbon nanoparticle-based, alternative, nontoxic imaging probe that is suitable for biological staining and diagnostics. We have developed a chemical method to synthesise highly fluorescent carbon nanoparticles 1-10 nm in size; these particles exhibit size-dependent, tunable visible emission. These carbon nanoparticles have been transformed into various functionalised nanoprobes with hydrodynamic diameters of 5-15 nm and have been used as cell imaging probes.
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The chemistry of graphene oxide
Dreyer, D. R., Park, S., Bielawski, C. W., & Ruoff, R. S. (2010) · Chem. Soc. Rev. · doi:10.1039/b917103g · Cited by 11,653
Design considerations for tumour-targeted nanoparticles
Choi, H. S., Liu, W., Liu, F., Nasr, K., Misra, P., Bawendi, M. G., & Frangioni, J. V. (2010) · Nature Nanotechnology · doi:10.1038/nnano.2009.314 · Cited by 754
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Zhu, S., Song, Y., Zhao, X., Shao, J., Zhang, J., & Yang, B. (2015) · Nano Research · doi:10.1007/s12274-014-0644-3 · Cited by 2,781
Georgakilas, V., Perman, J. A., Tucek, J., & Zboril, R. (2015) · Chemical Reviews · doi:10.1021/cr500304f · Cited by 2,147
An overview of nanoparticles commonly used in fluorescent bioimaging
Wolfbeis, O. S. (2015) · Chemical Society Reviews · doi:10.1039/c4cs00392f · Cited by 1,631
Carbon dots—Emerging light emitters for bioimaging, cancer therapy and optoelectronics
Hola, K., Zhang, Y., Wang, Y., Giannelis, E. P., Zboril, R., & Rogach, A. L. (2014) · Nano Today · doi:10.1016/j.nantod.2014.09.004 · Cited by 992
Crossing the blood-brain barrier with nanoparticles
Zhou, Y., Peng, Z., Seven, E. S., & Leblanc, R. M. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.12.015 · Cited by 837
Metadata
- Authors
- Bhunia, S. K., Saha, A., Maity, A. R., Ray, S. C., & Jana, N. R.
- Venue
- Scientific Reports
- Published
- 2013-03-18
- Volume
- 3
- Issue
- 1
- Pages
- 1473-1473
- ISSN
- 2045-2322 (ISSN-L)
- OpenAlex
- W2008400200
- Cited by
- 750
- References
- 2
- FWCI
- 31.97
- Type
- journal article
- Language
- en
- Open access
- gold
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- Bhunia, S. K., Saha, A., Maity, A. R., Ray, S. C., & Jana, N. R. (2013). Carbon Nanoparticle-based Fluorescent Bioimaging Probes. Scientific Reports. https://doi.org/10.1038/srep01473
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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