Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody

Luo, Wenjie, Liu, Wencheng, Hu, Xiaoyan, Hanna, Mary, Caravaca, April, Paul, Steven M.·2015·Scientific Reports
DOI 10.1038/srep11161

Cited by (241)

Items 201–241 of 241

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  5. Additional file 2 of Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease
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  6. Additional file 3 of Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
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  7. Additional file 2 of The fluorescent ligand bTVBT2 reveals increased p-tau uptake by retinal microglia in Alzheimer’s disease patients and AppNL−F/NL−F mice
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  8. Additional file 7 of Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
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  9. Additional file 6 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Li, Leike, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  10. Additional file 5 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Li, Leike, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  11. Additional file 2 of Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
    Sonja Fixemer, Corrado Ameli, Gaël Paul Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Gérardy, Jean-Jacques, Naguib Mechawar, Alexander Skupin, Mittelbronn, Michel et al. · 2022 · Figshare
  12. Additional file 3 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Leike Li, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  13. Additional file 2 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
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  14. Additional file 4 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
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  15. Additional file 1 of Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning
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  16. Additional file 10 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Leike Li, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  17. Additional file 1 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Leike Li, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  18. Additional file 8 of Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
    Sonja Fixemer, Corrado Ameli, Gaël Paul Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Gérardy, Jean-Jacques, Naguib Mechawar, Alexander Skupin, Mittelbronn, Michel et al. · 2022 · Figshare
  19. Additional file 8 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Li, Leike, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  20. Additional file 6 of Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
    Sonja Fixemer, Corrado Ameli, Gaël Paul Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Gérardy, Jean-Jacques, Naguib Mechawar, Alexander Skupin, Mittelbronn, Michel et al. · 2022 · Figshare
  21. Additional file 7 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Leike Li, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  22. Additional file 4 of Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
    Sonja Fixemer, Corrado Ameli, Gaël Paul Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Gérardy, Jean-Jacques, Naguib Mechawar, Alexander Skupin, Mittelbronn, Michel et al. · 2022 · Figshare
  23. Additional file 4 of Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease
    Garrett S. Gibbons, Kim, Soo-Jung, Wu, Qihui, Dawn M. Riddle, Susan N. Leight, Lakshmi N. Changolkar, Xu, Hong, Emily S. Meymand, Mia O’Reilly, Bin Zhang et al. · 2020 · Figshare
  24. Additional file 1 of Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease
    Garrett S. Gibbons, Kim, Soo-Jung, Wu, Qihui, Dawn M. Riddle, Susan N. Leight, Lakshmi N. Changolkar, Xu, Hong, Emily S. Meymand, Mia O’Reilly, Bin Zhang et al. · 2020 · Figshare
  25. Additional file 1 of The fluorescent ligand bTVBT2 reveals increased p-tau uptake by retinal microglia in Alzheimer’s disease patients and AppNL−F/NL−F mice
    Cristina Nuñez‐Diaz, Emelie Andersson, Nina Schultz, Dovilė Pocevičiūtė, Oskar Hansson, K. Peter R. Nilsson, Malin Wennström · 2024 · Figshare
  26. Additional file 9 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Li, Leike, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  27. Additional file 3 of Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease
    Garrett S. Gibbons, Kim, Soo-Jung, Wu, Qihui, Dawn M. Riddle, Susan N. Leight, Lakshmi N. Changolkar, Xu, Hong, Emily S. Meymand, Mia O’Reilly, Bin Zhang et al. · 2020 · Figshare
  28. Additional file 1 of Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
    Sonja Fixemer, Corrado Ameli, Gaël Paul Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Gérardy, Jean-Jacques, Naguib Mechawar, Alexander Skupin, Mittelbronn, Michel et al. · 2022 · Figshare
  29. Additional file 5 of Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer’s disease and dementia with Lewy bodies
    Sonja Fixemer, Corrado Ameli, Gaël Paul Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Gérardy, Jean-Jacques, Naguib Mechawar, Alexander Skupin, Mittelbronn, Michel et al. · 2022 · Figshare
  30. Additional file 11 of LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
    Zhao, Peng, Xu, Yuanzhong, Jiang, Lu-Lin, Fan, Xuejun, Ku, Zhiqiang, Leike Li, Liu, Xiaoye, Deng, Mi, Arase, Hisashi, Zhu, Jay-Jiguang et al. · 2022 · Figshare
  31. STING–IFN–CH25H lipid axis links innate immune activation to tau pathology
    Hao Chen, Li Fan, Man Ying Wong, Yohannes A. Ambaw, Jingjie Zhu, Kendra Norman, Pearly Ye, Nessa Foxe, Daphne Zhu, Yuansong Wan et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  32. A Joint Tau Propagation and Neuroinflammation Model Reinforces Inflammatory Modulation of Network-Driven Spread in Alzheimer’s Disease
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  34. Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathie
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