Drug target prioritization by perturbed gene expression and network information

Cited by (137)

Items 101–137 of 137

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2. Gene prioritization based on random walks with restarts and absorbing states, to define gene sets regulating drug pharmacodynamics from single-cell analyses
   Augusto Sales de Queiroz, Guilherme Sales Santa Cruz, Alain Jean‐Marie, Dorian Mazauric, Jérémie Roux, Frédéric Cazals · 2022 · PLoS ONE
3. Deep Reach Centrality: An Innovative Network Centrality Metric Grounded in Distance and Degree, with Its Performance Analysis Applied to the SARS-CoV-2 Protein–protein Interaction Network
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4. A Novel Approach to Differential Expression Analysis of Co-Occurrence Networks for Small-Sampled Microbiome Data
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6. TnP as a Multifaceted Therapeutic Peptide with System-Wide Regulatory Capacity
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7. Unlocking the potential of computational phenotypic drug discovery: methods, challenges, and future directions
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8. Identification of Differentially Expressed Subpathways using a Consensus Approach
   Panos Balomenos, Andrei Dragomir, Athanasios K. Tsakalidis, Anastasios Bezerianos · 2019 · IEEE International Conference on Bioinformatics and Bioengineering (BIBE)
9. Identification of differentially expressed subpathways via a bilevel consensus scoring of network topology and gene expression
   Panos Balomenos, Andrei Dragomir, Athanasios K. Tsakalidis, Anastasios Bezerianos · 2020 · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
10. Network-Based Drug Discovery Identifies Statins as a Repurposing Agent to Improve Activity of Current Therapies in Chronic Lymphocytic Leukemia.
    Neus Giménez, Rupal Tripathi, Ariadna Giró, Laia Rosich, Mònica López‐Guerra, Irene López‐Oreja, Heribert Playà-Albinyana, Fabián Arenas, José Manuel Mas, Patricia Pérez‐Galán et al. · 2020 · Research Square
11. Broad Applications of Network Embeddings in Computational Biology, Genomics, Medicine, and Health
    Akanksha Jaiswar, Devender Arora, Manisha Malhotra, Abhimati Shukla, Nivedita Rai · 2022
12. Estimation of Drug Treatment Effects on the Signaling Pathways
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13. Understanding Disease and Disease Relationships Using Transcriptomic Data
    Erin Oerton · 2018 · Apollo (University of Cambridge)
14. Machine Learning Techniques for Development of Drugs Against Coronavirus Disease 2019 (COVID-19): A Case Study Protocol
    Saurabh Sharma, Ajay Prakash, Phulen Sarma, Bikash Medhi · 2021 · Methods in pharmacology and toxicology
15. LEVELNET to Visualise, Explore and Compare Protein-Protein Interaction Networks
    Yasser Mohseni Behbahani, Paul Saighi, Flavia Corsi, Élodie Laine, Alessandra Carbone · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
16. Combating Viral Diseases in the Era of Systems Medicine
    Jane P. F. Bai, Ellen Y. Guo · 2022 · Methods in molecular biology
17. Faculty Opinions recommendation of A network-based approach to identify deregulated pathways and drug effects in metabolic syndrome.
    Saikat Chakrabarti · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
18. Network medicine approaches to diagnostics and therapeutics
    Asher Ameli · 2020
19. Peer Review #1 of "Network neighborhood operates as a drug repositioning method for cancer treatment (v0.1)"
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20. Peer Review #4 of "Network neighborhood operates as a drug repositioning method for cancer treatment (v0.2)"
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21. Peer Review #2 of "Network neighborhood operates as a drug repositioning method for cancer treatment (v0.2)"
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22. Peer Review #3 of "Network neighborhood operates as a drug repositioning method for cancer treatment (v0.1)"
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23. Peer Review #2 of "Network neighborhood operates as a drug repositioning method for cancer treatment (v0.1)"
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24. Herb-CMap: Novel Hot Diffusion Algorithm to Identify Bioactive Ingredients from Herbal Medicine Based on Gene Perturbation Profiling
    Yinyin Wang, Yihang Sui, Jiaqi Yao, Hong Jiang, Qimeng Tian, Yun Tang, Jing Ping Tang, Ning‐Hua Tan · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
25. Genetically-Proxied Lower PAR1 and Renal Phenotypes: A Drug-Target Mendelian Randomization Study
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26. Additional file 1 of Network hub-node prioritization of gene regulation with intra-network association
    Chang, Hung-Ching, Chu, Chiao-Pei, Lin, Shu-Ju, Hsiao, Chuhsing Kate · 2020 · Figshare
27. Additional file 2 of On the correspondence between the transcriptomic response of a compound and its effects on its targets
    Engler Hart, Chloe, Daniel Ence, David Healey, Domingo-Fernández, Daniel · 2024 · Figshare
28. Additional file 2 of Network hub-node prioritization of gene regulation with intra-network association
    Chang, Hung-Ching, Chu, Chiao-Pei, Lin, Shu-Ju, Hsiao, Chuhsing Kate · 2020 · Figshare
29. Additional file 3 of Machine learning prediction of oncology drug targets based on protein and network properties
    Zoltán Dezső, Ceccarelli, Michele · 2020 · Figshare
30. Additional file 1 of Machine learning prediction of oncology drug targets based on protein and network properties
    Zoltán Dezső, Ceccarelli, Michele · 2020 · Figshare
31. Additional file 2 of Relationship between drug targets and drug-signature networks: a network-based genome-wide landscape
    Chae Won Lee, Kim, Sung Min, Sa, Soonok, Myunghee Hong, Nam, Sang-Min, Han, Hyun Wook · 2023 · Figshare
32. Additional file 2 of Machine learning prediction of oncology drug targets based on protein and network properties
    Zoltán Dezső, Ceccarelli, Michele · 2020 · Figshare
33. Additional file 1 of On the correspondence between the transcriptomic response of a compound and its effects on its targets
    Engler Hart, Chloe, Daniel Ence, David Healey, Domingo-Fernández, Daniel · 2024 · Figshare
34. Additional file 1 of Relationship between drug targets and drug-signature networks: a network-based genome-wide landscape
    Chae Won Lee, Kim, Sung Min, Sa, Soonok, Myunghee Hong, Nam, Sang-Min, Han, Hyun Wook · 2023 · Figshare
35. Harnessing AI to fuse phenotypic signatures for drug target identification: progress in computational modeling
    Fengming Chen, Ranran Zhao, Xingxing Han, Huan Li, Zhishu Tang · 2026 · Briefings in Bioinformatics
36. New computational approaches to study the effect of genetic mutations on the topology of protein-protein interaction networks
    Yasser Mohseni Behbahani · 2022 · theses.fr (ABES)
37. FAIRsharing record for: Biomedical Entity Expansion, Ranking, and Explorations
    FAIRsharing Team, Zongliang Yue · 2018 · FAIRsharing.org