Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice
Poroyko, Valeriy A., Carreras, Alba, Khalyfa, Abdelnaby, Khalyfa, Ahamed A., Leone, Vanessa, Peris, Eduard, Almendros, Isaac, Gileles-Hillel, Alex, Qiao, Zhuanhong, Hubert, Nathaniel, Farré, Ramon, Chang, Eugene B., Gozal, David·2016·Scientific Reports
Cited by (476)
Items 301–400 of 476
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- Baihe Dihuang Tang as a therapeutic candidate for insomnia: Targeting gut dysbiosis and neuroendocrine dysfunctionLiuxi Chu, Qin Lu, Pingping Chen, Zunyong Feng, Ping Wu, Jiamen Shen, Yi Jiang, Yang Yang, Xiran Tan, Xiaomeng Wang et al. · 2025 · iMetaOmics.
- Mechanisms of Acetate in Alleviating SETDB1-Linked Neuroinflammation and Cognitive Impairment in a Mouse Model of OSAZhan Zhao, Li Xiang, Jau‐Shyong Hong, Yubao Wang, Jing Feng · 2025 · Journal of Inflammation Research
- VBayesMM: variational Bayesian neural network to prioritize important relationships of high-dimensional microbiome multiomics dataTung Dang, Artem Lysenko, Keith A. Boroevich, Tatsuhiko Tsunoda · 2025 · Briefings in Bioinformatics
- Alterations in gut microbial community structure in obstructive sleep apnea /hypopnea syndrome (OSAHS): A systematic review and meta-analysisAli Tahmasebi, Rasa Beheshti, Mohammadsina Mahmoudi, Mahan Jalilzadeh, Hanieh Salehi‐Pourmehr · 2025 · Respiratory Medicine
- Obesity and Gut MicrobiotaArslan Ahmad, Sakhawat Riaz, Muhammad Usama Tanveer · 2022 · IntechOpen eBooks
- Potential effect of inflammation on the failure risk of in vitro fertilization and embryo transfer among infertile womenJing Xie, Lailai Yan, Zixi Cheng, Lijuan Qiang, Jingjing Yan, Yingying Liu, Rong Liang, Jingxu Zhang, Zhiwen Li, Lili Zhuang et al. · 2018 · Human Fertility
- Is the Gut Microbiome a Target for Adjuvant Treatment of COVID-19?Kai Hilpert · 2021 · Biologics
- Obstructive Sleep Apnea and Atherosclerosis: Both the Gut Microbiome and Hypercapnia MatterIsaac Almendros, Núria Farré · 2017 · American Journal of Respiratory Cell and Molecular Biology
- Sleep, Circadian Disruption, and Microbial-Immune InteractionsReena Mehra, Mihaela Teodorescu · 2018 · CHEST Journal
- Association of habitual sleep duration with abnormal bowel symptoms: a cross-sectional study of the 2005–2010 national health and nutrition examination surveyGuimei Zhang, Sisi Wang, Ping Ma, Tuzhi Wang, Xizhe Sun, Xiaotao Zhang, Hongyao Li, Jiyang Pan · 2024 · Journal of Health Population and Nutrition
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- Contribution of Obstructive Sleep Apnea to Asthmatic Airway Inflammation and Impact of Its Treatment on the Course of AsthmaOctavian C. Ioachimescu · 2024 · Sleep Medicine Clinics
- Levilactobacillus brevis SG031 modulates mood-related behaviors and attenuates stress-related sleep disturbance and autonomic dysfunction via gut microbiota modulation in Wistar–Kyoto ratsChieh-Wen Chen, Hung‐Chang Chen, Sheng-Chieh She, Chun‐Ting Lai, Wei J. Chen, Terry B.J. Kuo, Cheryl C.H. Yang · 2024 · Life Sciences
- Eucalyptus essential oil exerted a sedative-hypnotic effect by influencing brain neurotransmitters and gut microbes via the gut microbiota-brain axisXiaojing Li, Yuanyi Zhang, Qian Zhang, Aizhi Cao, Jie Feng · 2024 · Frontiers in Pharmacology
- Evaluation the Possible Role of Interleukin-6 and Tumor Necrosis Factor- Alpha in Pathogenesis of Obstructive Sleep Apnea in Obese Patients: A Case-Control StudySara Minaeian, Soheil Rahmani Fard, Samaneh Ahsant, Taghi Riahi, Reyhaneh Taheri Tinjani, Yousef Alimohamadi, Siavash Kooranifar, Fatemeh Shamlou Mahmoudi, Ali Hosseinipour · 2022 · Galen Medical Journal
- Assessing the causal association between sleep apnea and the human gut microbiome composition: A two-sample Mendelian randomization studyMin Yu, Xuehui Chen, Xin Huang, Xuemei Gao · 2024 · SAGE Open Medicine
- Association of dietary insulin index (DII) and dietary insulin load (DIL) with circadian rhythm and quality of sleep among overweight and obese women: a cross-sectional studyAtieh Mirzababaei, Faezeh Abaj, Mina Radmehr, Moloud Ghorbani, Yasaman Aali, Asma Rajabi Harsini, Cain C. T. Clark, Khadijeh Mirzaei · 2024 · BMC Endocrine Disorders
- Sleep and the Microbiome: A Two-Way RelationshipNúria Farré, David Gozal · 2018 · Archivos de Bronconeumología
- Obstructive sleep apnea and hypertension: the role of gut microbiomePavel Šiarnik, Katarína Klobučníková, Imrich Mucska, Alžbeta Hlucháňová, Oto Hanus, Peter Turčáni, Branislav Kollár · 2020 · Vnitřní lékařství
- Sleep disorders in the acute phase of coronavirus disease 2019: an overview and risk factor studyCun Li, Hongbin Cai, Qing Tao Zhou, Hua-qiu Zhang, Man Wang, Huicong Kang · 2023 · Annals of General Psychiatry
- Optimizing Polycystic Ovarian Disorder (PCOD) Treatment with Personalized Lifestyle and Nutrition StrategiesMost Sufia Begum, Samira Areen · 2023 · Journal of Clinical Medical Research
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- The epidemiology of inflammatory bowel disease: exploring the impacts of environmental factorsJihye Park, Jae Hee Cheon · 2025 · The Korean Journal of Internal Medicine
- From alpha diversity to zeitgebers: Functional implications and potential mechanisms linking the gut microbiome to sleep and circadian disruption (Part II)Katherine A. Maki, Jennifer J. Barb, Shirleen Xu, Shreya Papneja, Jenna Alkhatib, Gisela Butera, Gwenyth Reid Wallen · 2026 · Neuroscience & Biobehavioral Reviews
- From alpha diversity to zeitgebers: Bacterial gut microbiome associations with sleep and circadian disruption (Part I)Katherine A. Maki, Jennifer J. Barb, Jenna Alkhatib, Gisela Butera, Gwenyth Reid Wallen · 2026 · Neuroscience & Biobehavioral Reviews
- Processed Diets and Food Additives Shape the Gut Microbiota and Chronic Disease Risk Across the Life Course—A Three-Layer Ecosystem Disruption Model (TLED) ModelMonica Profir, Luciana Alexandra Pavelescu, Gabriel Florin Răzvan Mogoș, Alin Constantin Stancu, Sanda Maria Creţoiu, Ileana P Marinescu · 2026 · Life
- Nomogram to diagnosis of obstructive sleep apnoea‐hypopnoea syndrome in high‐risk Chinese adult patientsJie Liu, Feng Pang, Xiaofeng Huang, Xiangmin Zhang, Minmin Lin, Wenmin Deng, Tianrun Liu, Zhen Long · 2023 · The Clinical Respiratory Journal
- Gut microbiota: a potential influencer of insomnia occurring after COVID-19 infectionJiale Fang, Siwen Wang, Lijia Liu, Xiaoyi Zhang, Ruilong Liu, Xingchao Pang, Jiankun Cui, Jianshu Han, Xinyu Zhu · 2024 · Frontiers in Psychiatry
- Catecholamine exposure and the gut microbiota in obstructive sleep apneaJoe Alcock, Dongdong Lin, Prashanth Setty, Lee K. Brown, Armand E. K. Dichosa, Benjamin J. Burnett, Cliff Shunsheng Han, Henry C. Lin · 2025 · PeerJ
- Identification of Rodent Husbandry Refinement Opportunities through Benchmarking and CollaborationNatalie A. Bratcher, Carolyn M Allen, Craig L McLahan, Denice M O'Connell, Holly N Burr, Jessica N Keen, Lisa M Stanislawczyk, Monika A. Burns · 2022 · Journal of the American Association for Laboratory Animal Science
- ‘Nocturomics’: transition to omics‐driven biomarkers of nocturia, a systematic review and future prospectsSusan Gong, George Bou Kheir, Abdo E. Kabarriti, Lakshay Khosla, Fred Gong, Erik VAN LAECKE, Jeffrey P. Weiss, Karel Everaert, François Hervé · 2023 · British Journal of Urology
- Sleep fragmentation disrupts Lyme arthritis resolution in miceChrista D. Jackson, Mohammad Badran, David Gozal, Charles R. Brown, Abdelnaby Khalyfa · 2024 · Sleep Medicine
- Goat casein hydrolysates alleviated insomnia in mice via modulating the level of neurotransmitters and the composition of gut microbiotaLing Mo, Huijuan Jing, Xiaojing Du, Chaochao Zhao, Yintao Lin, Jie Li, Hongxin Wang · 2024 · Food Science and Human Wellness
- Mind over Microbes: Investigating the Interplay between Lifestyle Factors, Gut Microbiota, and Brain HealthParul Bali, Parth Lal, Madhava Sai Sivapuram, L. V. Simhachalam Kutikuppala, Pramod Avti, Aarzoo Chanana, Saurabh Kumar, Akshay Anand · 2024 · Neuroepidemiology
- The phenomenon of intestinal permeability and its association with cardiovascular disease. Current statusDaria A. Kashtanova, О. Н. Ткачева · 2020 · CARDIOVASCULAR THERAPY AND PREVENTION
- Disease Implications of the Circadian Clocks and Microbiota InterfaceLaura B. Tran, Christopher B. Forsyth, Faraz Bishehsari, Robin M. Voigt, Ali Keshavarzian, Garth R. Swanson · 2021 · Springer eBooks
- Implications of microbe-mediated crosstalk in the gut: Impact on metabolic diseasesRoofia Beg, Katja Gonzalez, Kristina Martinez · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- The effect of disrupted sleep on macrophage polarization: a systematic review and meta-analysis of animal studiesMonireh Askarzadeh, Rezvan Yazdian Robati, Misagh Rajabinejad, Alireza Rafiei · 2025 · BMC Immunology
- The Beauty Sleep to Keep a Healthy LiverMariana Verdelho Machado · 2025 · International Journal of Molecular Sciences
- Gut microbiota composition correlates with insomnia severity: insights from high-throughput sequencing analysisZhe Xu, Jinxia Zhang, Haifang Zhou, Lei Zhang, Xin Zhang · 2026 · Frontiers in Microbiology
- Mechanisms Linking Sleep-Disordered Breathing and Cardiometabolic Disease RiskRahul Gomez, Wei Sun, Melody Shyy, Yu-Sin Jennifer Ou, Ameeta Sihota, B. Liu, Omar A. Mesarwi, Atul Malhotra · 2026 · Arteriosclerosis Thrombosis and Vascular Biology
- Bifidobacterium pseudolongum alleviates chronic intermittent hypoxia-induced cognitive impairment by restoring acetate metabolism and suppressing hippocampal neuroinflammation and neuronal PANoptosisTianning Sun, Rao Sun, JING YAN, Li Luo (149019), Mengxin Que, Xuan Wang (55634), Zilong Zhang, Shan Li, Zhiqiang Zhou, Yilin Zhao et al. · 2026 · Microbiological Research
- A Chrono-Metabolic Approach to Mental Health: Current Perspectives on Circadian Rhythms, Gut Microbiota, and Microbial Metabolites in Mood DisordersGiuseppe Marano, Mariateresa Acanfora, Luca Conci, Gianandrea Traversi, Osvaldo Mazza, Esmeralda Capristo, Eleonora Gaetani, Gianluca Franceschini, Marianna Mazza · 2026 · Metabolites
- The role of lncRNAs in intermittent hypoxia and sleep Apnea: A review of experimental and clinical evidenceMohammad‐Taher Moradi, Reza Fadaei, Amir Sharafkhaneh, Habibolah Khazaie, David Gozal · 2023 · Sleep Medicine
- Interplay between gut microbiota and exosome dynamics in sleep apneaR.R Hicks, David Gozal, Sarfraz Ahmed, Abdelnaby Khalyfa · 2025 · Sleep Medicine
- Insomnia Associated With Increased Risk of Atopic Dermatitis: A Two‐Sample Mendelian Randomization StudyXiuqin Ni, Xing Li, Jiayan Li · 2025 · Brain and Behavior
- Melatonin-mediated intestinal microbiota homeostasis improves skin barrier damage involvement of gut-skin axis dysfunction in aging miceTao Quan, Wenrui Zhang, Yanfeng Shi, Ting Gao · 2025 · Cellular Signalling
- Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuationsErika L. English, James M. Krueger · 2025 · Frontiers in Neuroscience
- Sleep and probiotics in diabetes managementBárbara Virginia Vitti-Ruela, Vinícius Dokkedal‐Silva, Aparecida Emiko Hirata, Sergio Brasil Tufik, Mônica L. Andersen · 2023 · Primary care diabetes
- Oral Administration of Human-Gut-Derived Prevotella histicola Improves Sleep Architecture in RatsDae Wui Yoon, Inkyung Baik · 2023 · Microorganisms
- Metabolomics and the Gut–Brain AxisGiorgia Caspani, Michael Harvey, Jonathan Richard Swann · 2024 · Elsevier eBooks
- Consumption of poly-γ-glutamate-vitamin B6 supplement and urinary microbiota profiles in Korean healthy adults: a randomized, double-blinded, placebo-controlled intervention studyJungmin Park, Inkyung Baik · 2024 · Nutrition Research and Practice
- Neurophysiology and Molecular Basis of Cognitive Behavioral Therapy for Patients with Insomnia: Implications for Non-Pharmacological ApproachesGuimei Zhang, Sisi Wang, Ping Ma, Jiyang Pan · 2024 · Journal of Integrative Neuroscience
- Gut microbiome, stress and interventional strategies using hardy animalsRuqaiyyah Siddiqui, Rizwan Qaisar, Sutherland Kester Maciver, Naveed Ahmed Khan · 2025 · Future Science OA
- Sleep-Related Breathing Disorders and Inflammation: TNF-α and IL-6 as Prototypic ExamplesDavid Gozal, Hui‐Leng Tan, David Gozal · 2019 · Springer eBooks
- Is a “gut full” of bad bugs driving metabolic disease in shift workers?Craig L. Phillips, Maria Comas · 2017 · Sleep Medicine Reviews
- Examining the Relationships Between Sleep Physiology and the Gut Microbiome in Preclinical and Translational Research: Protocol for a Scoping ReviewKatherine A. Maki, Jenna Alkhatib, Gisela Butera, Gwenyth Reid Wallen · 2022 · JMIR Research Protocols
- Sleep, gut microbiota, and mind-body medicineMonalisa Das, Gangatharan Muralitharan, Sarashti Saini, Sanjib Patra · 2025 · Brain Behavior and Immunity Integrative
- Limosilactobacillus reuteri ATG-F4 Improves the Muscle Strength and Muscle Mass of Mice with Immobilization-Induced Muscular AtrophyDae‐Young Lee, Young‐Sil Lee, Gun-Seok Park, Juyi Park, Seung-Hyun Ko, You-Kyung Lee, Do Yeun Jeong, Yong Hyun Lee, Jihee Kang · 2025 · Journal of Microbiology and Biotechnology
- Preliminary analysis of gut microbiome characteristics in children with obstructive sleep apnea hypopnea syndromeZhihui Wang, Luting Zhou, Yanyu He, Xueyun Xv, Meng Lv, Zhen Zhang, Fengqian Wang, Shuqi Wang, Yuqing Wang · 2025 · Frontiers in Neurology
- Gut microbial metabolites, barrier dysfunction, and endotoxemia in men obstructive sleep apnea-associated hypertensionChih‐Yuan Ko, Li Zhang, Ying Lin, Yiming Zeng · 2026 · iScience
- Berberine-gut microbiota interactions based on CiteSpace: current research status and hotspotsYan Chen, Tao Chen, S. J. Tian, Ling Tao, Fangfang Fan, Yuanyong Yang, Xiangchun Shen · 2026 · Frontiers in Microbiology
- Understanding gut microbiota dysbiosis as a plausible link between obstructive sleep apnea (OSA), viral infections, and lifestyle diseasesShivram Karthik S, Pranay Jadhav, Anurag Paul, Rohit Kumar, Debarati Paul, Sudeep Bose · 2026 · Microbial Pathogenesis
- Sleep loss as a cardiometabolic risk factor: a narrative review of clinical and public health implicationsFiras K. Ghanem, Hrayr Pierre Attarian, Zeina Al-Khalil, Colette S. Kabrita · 2026 · Journal of Clinical Sleep Medicine
- Gut Dysbiosis in Insomnia and Diurnal CycleRajesh Kumar · 2022 · Springer eBooks
- Gut Microbiome and Insomnia: A Mini-ReviewNoor Yaser Asaad, Maram Walid Ballan, Heba Eyad Shalabi, Ashfaque Hossain · 2022 · New Emirates Medical Journal
- Gut check: assessing the role of the gut microbiota in the adverse cardiovascular effects of obstructive sleep apnoeaDavid J. Durgan, Ramón Farré · 2023 · European Respiratory Journal
- Appraising the Effects of Gut Microbiota on Insomnia Risk Through Genetic Causal AnalysisPeihong Li, Song Wang, Jiaxin Li, Zheng Xiao, Haoyue Zhu, Dandan Sheng, Weiping Liu, Bo Xiao, Luo Zhou · 2025 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
- Pathophysiological Mechanisms in Obstructive Sleep Apnea SyndromeDemet Aygün · 2025 · BENTHAM SCIENCE PUBLISHERS eBooks
- Advances in the Study of Immune Function in Obstructive Sleep Apnea-Hypopnea Syndrome新新 姜 · 2022 · Advances in Clinical Medicine
- Neurobiology of Sleep and Microbiomics in AgingLinda J. Larson‐Prior, Gohar Azhar, David Davila, Se‐Ran Jun, Aaron S. Kemp, Intawat Nookaew, Jeanne Y. Wei, Trudy M. Wassenaar · 2017 · OBM Neurobiology
- Sueño y microbioma: una relación bidireccionalNúria Farré, David Gozal · 2018 · Archivos de Bronconeumología
- From Alpha Diversity to ZZZ: Exploring associations among sleep, gut bacteria and behavioral development in infancySarah Fiona Schoch, Josué L. Castro-Meija, Łukasz Krych, Witold Kot, Bingfeng Leng, Malcolm Kohler, Reto Huber, Gerhard Rogler, Luc Biedermann, Jean‐Claude Walser et al. · 2021
- Targeting gut microbiome, is it always a therapeutic option?Alba Rodríguez‐Nogales, Júlio Gálvez · 2020 · EBioMedicine
- Changes in gut microbiota composition and their associations with cortisol, melatonin and interleukin 6 in patients with chronic insomniaAA Masyutina, Гуменюк Леся Николаевна, Ю. В. Фатовенко, Л. Е. Сорокина, Байрамова Сабина Саяровна, AI Alekseenko, Ю. В. Шавров, А. А. Романова, Д. И. Сейдаметова · 2021 · Bulletin of Russian State Medical University
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- Obstructive sleep apnoea as a neuromuscular respiratory disease arising from an excess of central GABAergic neurotransmitters: a new disease modelDomenico Maurizio Toraldo, Alessandra Palma Modoni, Egeria Scoditti, Francesco De Nuccio · 2025 · Frontiers in Cellular Neuroscience
- Pathophysiological Mechanisms Linking Obstructive Sleep Apnea to Nonalcoholic Fatty Liver DiseaseEptehal Mohammed Dongol, Fatma Rabea A Hamdan, Osmanuddin Ahmed, Rehab H. Abdel-Aziz, Mahitab Younes, Rana Toghan · 2025 · Sleep Medicine Research
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- Strategies for Scientific and Practicall Search: is There Any Correlation Between the Development of the Gut-Brain Axis and the Sleep Characteristics in Infants?Irina A. Belyaeva, Tatiana V. Turti, Бомбардирова Елена Петровна, Pavel E. Sadchikov, Alexander Yu. Nagonov · 2021 · Вопросы современной педиатрии
- Impact of sleep fragmentation, heart failure, and their combination, on the gut microbiomeOlfat Khannous‐Lleiffe, Jesse R. Willis, Ester Saus, Ignacio Cabrera-Aguilera, Isaac Almendros, Ramón Farré, David Gozal, Núria Farré, Toni Gabaldón · 2020 · bioRxiv (Cold Spring Harbor Laboratory)