Development and characterization of a microfluidic model of the tumour microenvironment

Ayuso, Jose M., Virumbrales-Muñoz, María, Lacueva, Alodia, Lanuza, Pilar M., Checa-Chavarria, Elisa, Botella, Pablo, Fernández, Eduardo, Doblare, Manuel +5 more·2016·Scientific Reports

Cited by (133)

Items 101–133 of 133

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    Jacobo Ayensa-Jiménez, Marina Pérez-Aliacar, Teodora Ranđelović, Jose A. Sanz‐Herrera, Mohamed Hamdy Doweidar, M. Doblaré · 2020 · Mathematics
  2. Evolution of toxicity testing platforms from 2D to advanced 3D bioprinting for safety assessment of drugs
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  3. Sphéroïdes : le modèle de référence pour la culture in vitro des tumeurs solides ?
    Christian‐Jacques Larsen · 2017 · Bulletin du Cancer
  4. A Mathematical Modelling Study of Chemotactic Dynamics in Cell Cultures: The Impact of Spatio-temporal Heterogeneity
    Jacobo Ayensa-Jiménez, Mohamed Hamdy Doweidar, M. Doblaré, Eamonn A. Gaffney · 2023 · Bulletin of Mathematical Biology
  5. Computational model of the cancer necrotic core formation in a tumor-on-a-chip device
    Elton Bonifácio, CLEUDMAR ARAÚJO, Marcília Valéria Guimarães, Márcio Peres de Souza, Thiago Parente Lima, Bethânia Alves de Avelar Freitas, Libardo Andrés González Torres · 2024 · Journal of Theoretical Biology
  6. Tumor xenografts as the model for a preclinical trials of genetically modified cell therapy
    Valeriy Tereshchenko, Sergey Vitalievich Sennikov · 2021 · Immunologiya
  7. Dual-channel six-step linear concentration gradient microfluidic chip for orthogonal combination drug screening in head and neck tumor cells
    Jingru Liao, Zhimi Zhang, Guiquan Zhu, Dan Liu, Zhihao Tu, Wangang Zhu, Tao Dong, Ling Li, Zhuqing Wang · 2025 · Lab on a Chip
  8. 3D Cell Culture Systems for the Development of Neural Interfaces
    Omaer Syed, Chris Chapman, Catalina Vallejo‐Giraldo, Martina Genta, Josef A. Goding, Emmanuel Kanelos, Rylie A. Green · 2020 · Springer eBooks
  9. An Overview from Physically-Based to Data-Driven Approaches of the Modelling and Simulation of Glioblastoma Progression in Microfluidic Devices
    Jacobo Ayensa-Jiménez, Marina Pérez-Aliacar, Mohamed Hamdy Doweidar, Eamonn A. Gaffney, M. Doblaré · 2025 · Archives of Computational Methods in Engineering
  10. A mechanobiological model for tumor spheroids evolution: application to glioblastoma
    Ana Carrasco-Mantis, Héctor Alfonso Castro-Abril, Teodora Ranđelović, Ignacio Ochoa, M. Doblaré, Jose A. Sanz‐Herrera · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  11. A hypoxic microfluidic organoid-on-a-chip system for studying the efficacy of metronidazole-modified nanomaterials against cholangiocarcinoma established within the chip
    Ao Xie, Zipeng Yao, Qijun Du, Mengjiao Xia, Qinrui Lu, Jiashu Wang, Wenqi Hu, Lin Wu, Chenwei Sun, Youlong Yang et al. · 2026 · Lab on a Chip
  12. Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery
    Amina Benaicha-Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck-Iriart, Esther Masiá, Paula Carrascosa-Marco, Pablo Juanes‐Velasco, Snežana Đorđević et al. · 2026 · Advanced Functional Materials
  13. Microfluidics and Cancer Treatment: Emerging Concept of Biomedical Engineering
    Pratik V. Tawade, Nimisha Tondapurkar · 2023 · Biological and medical physics, biomedical engineering
  14. On the Simulation of Organ-on-Chip Cell Processes
    Jacobo Ayensa-Jiménez, Mohamed Hamdy Doweidar, Teodora Ranđelović, Luis José Fernández, Sara Oliván, Ignacio Ochoa, M. Doblaré · 2019 · Elsevier eBooks
  15. Optimization of long-term Breast Cancer Cell Culture using live Imaging in an automated Perfusion System
    Darío Ruarte · 2020 · Journal of Science Humanities and Arts - JOSHA
  16. Additive manufacturing of microfluidics for evaluation of immunotherapy efficacy
    Ashley L. Beckwith · 2018 · DSpace@MIT (Massachusetts Institute of Technology)
  17. Generation of nonlinear and spatially-organized 3D cultures on a microfluidic chip using photoreactive thiol-ene and methacryloyl hydrogels
    Jennifer E. Ortiz-Cárdenas, Jonathan M. Zatorski, Abhinav Arneja, Alyssa N. Montalbine, Jennifer M. Munson, Chance John Luckey, Rebecca R. Pompano · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  18. On-chip perivascular niche with patient-derived glioma cells
    Magda Gerigk, Harry J. C. J. Bulstrode, Haotian Shi, Felix Tönisen, Camilla Cerutti, Gillian M. Morrison, David H. Rowitch, Yan Yan Shery Huang · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  19. On chip complex breast tumour microenvironment: application to research in nanomedicine
    Jean-Baptiste Blondé · 2020
  20. 'I get by with a little help from my friends': The role of stromal cells in the breast cancer chemoresistance mechanism
    Helena Abolins-Thompson · 2022
  21. On the equivalence between agent-based and continuum models for cell population modeling. Application to glioblastoma evolution in microfluidic devices
    Raquel B. Arroyo-Vázquez, Marina Pérez-Aliacar, Jacobo Ayensa-Jiménez, M. Doblaré · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  22. Evaluation of Chloroquine and Hydroxychloroquine Efficacy on Chemotherapy Treatment in triple negative Breast Cancer by continuous live Cell Imaging
    Amina Poplata · 2021 · Journal of Science Humanities and Arts - JOSHA
  23. Mimicking and surpassing the cancer xenograft model with dynamic, in vivo-like, drug concentrations on-chip
    Job Komen · 2022
  24. Microfluídica inteligente: combinación del aprendizaje profundo y la microfluídica para predecir la evolución del glioblastoma.
    Marina Pérez-Aliacar, Mohamed Hamdy Doweidar, M. Doblaré, Jacobo Ayensa-Jiménez · 2021 · Jornadas de jóvenes investigadores del I3A
  25. Massive data probabilistic framework for parameter estimation in biological problems
    Marina Pérez-Aliacar, Jacobo Ayensa-Jiménez, Mohamed Hamdy Doweidar, M. Doblaré · 2023 · Elsevier eBooks
  26. Modelagem computacional de cultura de células tumorais em dispositivos de microfluídica utilizando o método dos elementos finitos
    Elton Bonifácio · 2023
  27. Pharmacological Strategies for Targeting Cancer Cell Migration and Invasion
    Roger M. Phillips · 2024 · Learning materials in biosciences
  28. Hypoxia-on-chip : from technological developments to biological applications
    Charlotte Bouquerel · 2023 · theses.fr (ABES)
  29. 3D numerical modeling of glioblastoma cells progression in microfluidic devices
    E. Sala-Lardies, J. Sarrate, Marina Pérez-Aliacar, Jacobo Ayensa-Jiménez, M. Doblaré, N. Parés · 2026 · Finite Elements in Analysis and Design
  30. From single cell analysis to 3D micro physiological systems: microfluidic tools integrating cancer cell targets for delineating natural killer cell biology
    Maria Victoria Hangad, H F Ma, Sam K. P. Kung, Francis Lin · 2026 · Microsystems & Nanoengineering
  31. 3D bioprinting and development of glioblastoma treatment models: a systematic review
    George Agiotis, Konstantinos Terlemes, Mikaella Shakalli, Vasileios K. Kavouridis, Georgios Fotakopoulos, Evangelos Kogias · 2026 · Bioprinting
  32. Ketogenic Diet as an Adjuvant in Epithelial Cancers: Mechanisms, Model Systems, and Translational Opportunities
    Timo J. Ylikomi, Matthias Nees · 2026 · Cancers
  33. Automated assessment of tumor spheroids via electrical impedance spectroscopy
    Ahmed Khattab, Ruth Grabowski, Ha Un Chung, Tobias Schmidt, Mai Thu Bui, Christian Schmees, Günther M. Zeck · 2026 · Sensing and Bio-Sensing Research