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Cited by 448

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Novel amperometric glucose biosensor based on MXene nanocomposite

Open access
Rakhi, R. B., Nayak, Pranati, Xia, Chuan, Alshareef, Husam N.·2016·Scientific Reports

Abstract

A biosensor platform based on Au/MXene nanocomposite for sensitive enzymatic glucose detection is reported. The biosensor leverages the unique electrocatalytic properties and synergistic effects between Au nanoparticles and MXene sheets. An amperometric glucose biosensor is fabricated by the immobilization of glucose oxidase (GOx) enzyme on Nafion solubilized Au/ MXene nanocomposite over glassy carbon electrode (GCE). The biomediated Au nanoparticles play a significant role in facilitating the electron exchange between the electroactive center of GOx and the electrode. The GOx/Au/MXene/Nafion/GCE biosensor electrode displayed a linear amperometric response in the glucose concentration range from 0.1 to 18 mM with a relatively high sensitivity of 4.2 μAmM−1 cm−2 and a detection limit of 5.9 μM (S/N = 3). Furthermore, the biosensor exhibited excellent stability, reproducibility and repeatability. Therefore, the Au/MXene nanocomposite reported in this work is a potential candidate as an electrochemical transducer in electrochemical biosensors.

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Metadata

Authors
Rakhi, R. B., Nayak, P., Xia, C., & Alshareef, H. N.
Venue
Scientific Reports
Published
2016-11-10
Volume
6
Issue
1
Pages
36422-36422
ISSN
2045-2322 (ISSN-L)
OpenAlex
W2555857612
Cited by
448
References
1
FWCI
12.20
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Novel amperometric glucose biosensor based on MXene nanocomposite. https://app.cochat.ai/papers/10.1038/srep36422
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Rakhi, R. B., Nayak, P., Xia, C., & Alshareef, H. N. (2016). Novel amperometric glucose biosensor based on MXene nanocomposite. Scientific Reports. https://doi.org/10.1038/srep36422

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