Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia

Tarabeux, J, Kebir, O, Gauthier, J, Hamdan, F F, Xiong, L, Piton, A, Spiegelman, D, Henrion, É +15 more·2011·Translational Psychiatry

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  3. Oligogenic rare variant contributions in schizophrenia and their convergence with genes harbouring de novo mutations in schizophrenia, autism and intellectual disability: Evidence from multiplex families
    Jibin John, Prachi Kukshal, Triptish Bhatia A, Ricardo Harripaul, Vishwajit Laxmikant Nimgaonkar, S.N. Deshpande, Bittianda Kuttapa Thelma · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  4. Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids
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  5. Genetics of Autism Spectrum Disorder underscores the role of altered spontaneous neuronal activity as a catalyst for the neurodevelopmental anomalies
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  6. Positive modulators of N -methyl- d -aspartate receptor: structure–activity relationship study on steroidal C-17 and C-20 oxime ethers
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  7. Beyond categorical boundaries: Common molecular and cellular pathways in autism spectrum disorder and schizophrenia
    Nahi Sabih Alruwaili, Hayder M. Al‐kuraishy, Ali Ismail Al-Gareeb, Mustafa M Shokr, Neda M. Bogari, Suhair Alhelfawi, Mubarak Alruwaili, Gaber El‐Saber Batiha · 2026 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  8. NMDA Receptors in Health and Disease
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  9. Article Open Access
    Holly Lawford‐Smith · 2015
  10. Consequences of NMDA Receptor Disruption for Prefrontal Cortical Neurophysiology
    Mary A. Binko · 2018 · TSpace (University of Toronto)
  11. White Matter Neurons: mRNA Expression and Analysis
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  12. Microbial ecology of prawn aquaculture - sediment, water, and water treatment
    Linda L. Blackall, Justice C.F. Baiano · 2002
  13. Unpacking The Autism Spectrum Disorder Profile of Children With De Novo Disruptive GRIN2B Variants: A Quantitative and Qualitative Analysis
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  14. The Glutamatergic System
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  15. Neuronal Endosomal Trafficking: One of the Common Molecular Pathways Disrupted in Autism Spectrum Disorders and Schizophrenia
    2016 · Journal of Neurology and Psychology
  16. Phenotype of mice carrying an NMDA receptor GluN2B protein-truncating variant associated with intellectual disability
    Klevinda Fili, Viktor Kuchtiak, Eni Tomović, Miriam Candelas, Agnieszka Kubik‐Zahorodna, Karel Harant, Paulína Božíková, Jiří Černý, Miloslav Kořı́nek, Barbora Hrčka Krausová et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  17. Analysis of microRNA-transcript regulatory networks in the hippocampus of the BTBR mouse model of autism
    Silvia Gasparini, Valerio Licursi, Arianna Rinaldi, Laura Ricceri, María Luisa Scattoni, Carlo Presutti, Cecilia Mannironi · 2025 · Frontiers in Cellular Neuroscience
  18. Psychopathology in Persons with Intellectual Disability and Autism Spectrum Disorder
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  19. SynThIA: A semi-automated tool for quantification of multi-partite synapses
    Max Neather, James Morgan, Fong Kuan Wong · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  20. NGS-based approaches for the diagnosis of intellectual disability and other genetically heterogeneous developmental disorders
    Claire E. Redin · 2014 · theses.fr (ABES)
  21. Impact of psychotomimetic molecules on glutamatergic N-Methyl-D-Aspartate receptors surface trafficking
    Julie Jézéquel · 2016 · theses.fr (ABES)
  22. Role of early-life stress and metabotropic glutamate receptors in the developmental trajectory of the central nervous system
    Rémy Verhaeghe · 2020
  23. Autism-linked protein POSH balances NMDAR signaling via a self-limiting kinase-scaffold loop
    Minghui Yao, Shuo Wang, Feng Zhang, Lei Shi, Zhiheng Xu · 2026 · iScience
  24. Rôle du zinc dans la transmission synaptique normale et pathologique
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  25. Upregulated GluN2C-NMDARs in a model of focal cortical dysplasia type II drive neuronal hyperexcitability
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  26. Identification of rare missense variants of ionotropic glutamate receptor N-methyl-D-aspartate 2 genes in patients with schizophrenia
    Chia‐Liang Wu, Tsung‐Ming Hu, Shih-Hsin Hsu, Hsin-Yao Tsai, Min-Chih Cheng · 2026 · Psychiatric Genetics
  27. The Molecular Machinery of Synaptic Plasticity and Its Potential Role in the Aetiology of Schizophrenia
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  28. Mechanism of activity inversion for GluN2B-selective negative allosteric modulators
    Steven A. Kell, Scott J. Myers, Yesim A. Tahirovic, Cara A. Mosley, Rose Santangelo, Dennis C. Liotta, Stephen F. Traynelis · 2026 · Molecular Pharmacology
  29. Unravelling autism: A holistic review of diagnosis, management, strength and future directions
    Nikita Thakur, Jyoti Monga, Dipan Roy, Deepika Choudhary, Surpreet Kaur, Naresh Kumar Rangra · 2026 · Scripta Medica
  30. A Comprehensive Analysis of the Relationship Between Dietary Fatty Acids and Changes in the Gut Microbiota and the Development of Neuropsychiatric Disorders
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  31. BindingDB Entry 50002704: Positive Modulators of the N-Methyl-d-aspartate Receptor: Structure-Activity Relationship Study of Steroidal 3-Hemiesters.
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  32. Functional Deficits and Diffusion Tensor Magnetic Resonance Imaging of the Olfactory and Vision Systems in the Alzheimer’s Disease Model of Aging GluN3A Knockout Mice
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