The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Oxidizing species in the mechanism of cytochrome P450
Abstract
This review discusses the mechanisms of oxygen activation by cytochrome P450 enzymes, the possible catalytic roles of the various iron--oxygen species formed in the catalytic cycle, and progress in understanding the mechanisms of hydrocarbon hydroxylation, heteroatom oxidation, and olefin epoxidation. The focus of the review is on recent results, but earlier work is discussed as appropriate. The literature through to February 2002 is surveyed, and 175 referenced are cited.
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Citations
Cites
Mechanistic studies on aromatase and related CC bond cleaving P-450 enzymes
Akhtar, M., Njar, V. C. O., & Neville Wright, J. (1993) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/0960-0760(93)90241-n · Cited by 193
Cited by
Structure and chemistry of cytochrome p450
Denisov, I. G., Makris, T. M., Sligar, S. G., & Schlichting, I. (2005) · Chemical Reviews · doi:10.1021/cr0307143 · Cited by 2,106
P450 Enzymes: Their Structure, Reactivity, and Selectivity—Modeled by QM/MM Calculations
Shaik, S., Cohen, S., Wang, Y., Chen, H., Kumar, D., & Thiel, W. (2010) · Chemical Reviews · doi:10.1021/cr900121s · Cited by 1,083
Reactivity of High-Valent Iron–Oxo Species in Enzymes and Synthetic Reagents: A Tale of Many States
Shaik, S., Hirao, H., & Kumar, D. (2007) · Accounts of Chemical Research · doi:10.1021/ar600042c · Cited by 555
Biosynthesis and function of polyacetylenes and allied natural products
Minto, R. E., & Blacklock, B. J. (2008) · Progress in Lipid Research · doi:10.1016/j.plipres.2008.02.002 · Cited by 351
Schöneboom, J. C., Neese, F., & Thiel, W. (2005) · Journal of the American Chemical Society · doi:10.1021/ja0424732 · Cited by 260
Metadata
- Authors
- Ortiz de Montellano, P. R., & De Voss, J. J.
- Venue
- Natural Product Reports
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2002-05-09
- Volume
- 19
- Issue
- 4
- Pages
- 477-493
- ISSN
- 0265-0568 (ISSN-L)
- 1460-4752
- OpenAlex
- W2146702232
- Cited by
- 317
- References
- 1
- FWCI
- 15.19
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.