The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
The application of micro reactors for organic synthesis
Abstract
This tutorial review describes how micro reactors are being applied to synthetic chemistry covering a wide range of applications, from the preparation of nanograms of material for drug discovery and screening to the multi-tonne production of fine chemicals. This article explores how miniaturisation may revolutionise chemical synthesis and demonstrates that products are generated in higher yield and purity compared to the equivalent bulk reactions, in much shorter periods of time.
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Citations
Cites
Chemistry in Microstructured Reactors
Jähnisch, K., Hessel, V., Löwe, H., & Baerns, M. (2004) · Angewandte Chemie International Edition · doi:10.1002/anie.200300577 · Cited by 1,286
Micro reactors: principles and applications in organic synthesis
Fletcher, P. D. I., Haswell, S. J., Pombo-Villar, E., Warrington, B. H., Watts, P., Wong, S. Y. F., & Zhang, X. (2002) · Tetrahedron · doi:10.1016/s0040-4020(02)00432-5 · Cited by 468
Self-citationSuga, S., Okajima, M., Fujiwara, K., & Yoshida, J.-I. (2001) · Journal of the American Chemical Society · doi:10.1021/ja015823i · Cited by 246
Microreactors for elemental fluorine
Chambers, R. D., & Spink, R. C. H. (1999) · Chemical Communications · doi:10.1039/a901473j · Cited by 214
Photochemical reactions and on-line UV detection in microfabricated reactors
Lu, H., Schmidt, M. A., & Jensen, K. F. (2001) · Lab on a Chip · doi:10.1039/b104037p · Cited by 210
Microfabricated Multiphase Reactors for the Selective Direct Fluorination of Aromatics
de Mas, N., Günther, A., Schmidt, M. A., & Jensen, K. F. (2003) · Industrial & Engineering Chemistry Research · doi:10.1021/ie020717q · Cited by 185
A Microfabricated Nanoreactor for Safe, Continuous Generation and Use of Singlet Oxygen
Wootton, R. C. R., Fortt, R., & de Mello, A. J. (2002) · Organic Process Research & Development · doi:10.1021/op0155155 · Cited by 167
Production of titania nanoparticles by using a new microreactor assembled with same axle dual pipe
Takagi, M., Maki, T., Miyahara, M. T., & Mae, K. (2004) · Chemical Engineering Journal · doi:10.1016/j.cej.2003.11.011 · Cited by 142
Chambers, R. D., Holling, D., Spink, R. C. H., & Sandford, G. (2001) · Lab on a Chip · doi:10.1039/b108841f · Cited by 139
McCreedy, T. (2001) · Analytica Chimica Acta · doi:10.1016/s0003-2670(00)01174-0 · Cited by 124
Cited by
Enzyme Immobilization: The Quest for Optimum Performance
Sheldon, R. A. (2007) · Advanced Synthesis & Catalysis · doi:10.1002/adsc.200700082 · Cited by 2,077
Greener Approaches to Organic Synthesis Using Microreactor Technology
Mason, B. P., Price, K. E., Steinbacher, J. L., Bogdan, A. R., & McQuade, D. T. (2007) · Chemical Reviews · doi:10.1021/cr050944c · Cited by 985
Flash Chemistry: Fast Chemical Synthesis by Using Microreactors
Yoshida, J., Nagaki, A., & Yamada, T. (2008) · Chemistry – A European Journal · doi:10.1002/chem.200800582 · Cited by 537
Alonso, F., Beletskaya, I. P., & Yus, M. (2008) · Tetrahedron · doi:10.1016/j.tet.2007.12.036 · Cited by 532
Alonso, F., Beletskaya, I. P., & Yus, M. (2005) · Tetrahedron · doi:10.1016/j.tet.2005.08.054 · Cited by 498
Metadata
- Authors
- Watts, P., & Haswell, S. J.
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2005
- Volume
- 34
- Issue
- 3
- Pages
- 235
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2331825725
- Cited by
- 384
- References
- 18
- FWCI
- 2.27
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.