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Cited by 185

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Self-assembly and applications of biomimetic and bioactive peptide-amphiphiles

Kokkoli, Efrosini, Mardilovich, Anastasia, Wedekind, Alison, Rexeisen, Emilie L., Garg, Ashish, Craig, Jennifer A.·2006·Soft Matter

Abstract

Peptide-amphiphiles are amphiphilic structures with a hydrophilic peptide headgroup that incorporates a bioactive sequence and has the potential to form distinct structures, and a hydrophobic tail that serves to align the headgroup, drive self-assembly, and induce secondary and tertiary conformations. In this paper we review the different self-assembled structures of peptide-amphiphiles that range from micelles and nanofibers, to patterned membranes. We also describe several examples where peptide-amphiphiles have found applications as soft bioactive materials for model studies of bioadhesion and characterization of different cellular phenomena, as well as scaffolds for tissue engineering, regenerative medicine, and targeted drug delivery.

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Crossref · 10.1039/b608929a

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Metadata

Authors
Kokkoli, E., Mardilovich, A., Wedekind, A., Rexeisen, E. L., Garg, A., & Craig, J. A.
Venue
Soft Matter
Published
2006
Volume
2
Issue
12
Pages
1015
ISSN
  • 1744-683X (ISSN-L)
  • 1744-6848
OpenAlex
W2141320224
Cited by
185
References
1
FWCI
5.59
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Self-assembly and applications of biomimetic and bioactive peptide-amphiphiles. https://app.cochat.ai/papers/10.1039/b608929a
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Kokkoli, E., Mardilovich, A., Wedekind, A., Rexeisen, E. L., Garg, A., & Craig, J. A. (2006). Self-assembly and applications of biomimetic and bioactive peptide-amphiphiles. Soft Matter. https://doi.org/10.1039/b608929a

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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