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Strategies to improve the response rate of thermosensitive PNIPAAm hydrogels
Abstract
Poly(N-isopropylacrylamide) (PNIPAAm) hydrogel is one of the most extensively studied thermosensitive hydrogels, it displays a lower critical solution temperature (LCST) at around 33 °C in aqueous solution and undergoes an abrupt thermoreversible change in volume as the external temperature cycles around this critical temperature. The fast response rate of hydrogels is critically important in some applications, such as artificial organs, actuators, and on-off switches. In this article, we review different strategies, including physical and chemical strategies, for improving the response kinetics of PNIPAAm-based hydrogels. Based on the numerous strategies, the factors that are essential to achieve the fast response rate are identified.
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Cited by
Designing degradable hydrogels for orthogonal control of cell microenvironments
Kharkar, P. M., Kiick, K. L., & Kloxin, A. M. (2013) · Chem. Soc. Rev. · doi:10.1039/c3cs60040h · Cited by 717
Deng, Z., Hu, T., Lei, Q., He, J., Ma, P. X., & Guo, B. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b20178 · Cited by 486
Metadata
- Authors
- Zhang, X.-Z., Xu, X.-D., Cheng, S.-X., & Zhuo, R.-X.
- Venue
- Soft Matter
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2008
- Volume
- 4
- Issue
- 3
- Pages
- 385
- ISSN
- 1744-683X (ISSN-L)
- 1744-6848
- OpenAlex
- W1970217459
- Cited by
- 170
- References
- 0
- FWCI
- 4.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhang, X.-Z., Xu, X.-D., Cheng, S.-X., & Zhuo, R.-X. (2008). Strategies to improve the response rate of thermosensitive PNIPAAm hydrogels. Soft Matter. https://doi.org/10.1039/b713803m
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