The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Novel strategies for the site-specific covalent labelling of nucleic acids
Open accessAbstract
To broaden the scope of applications in DNA nano- and biotechnology, material science, diagnostics and molecular recognition the functionalization of DNA is of utmost importance. In the last decade many new methods have been developed to achieve this goal. Apart from the direct chemical synthesis of modified DNA by automated phosphoramidite chemistry incorporation of labelled triphosphates and the post-synthetic labelling approach evolved as valuable methods. New bioorthogonal reactions as Diels-Alder, click and Staudinger ligations pushed forward the post-synthetic approach as new insights into DNA polymerase substrate specificity allowed generation and amplification of labelled DNA strands. These novel developments are summarized herein.
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Cites
Tornøe, C. W., Christensen, C., & Meldal, M. (2002) · The Journal of Organic Chemistry · doi:10.1021/jo011148j · Cited by 8,696
Oxidative Nucleobase Modifications Leading to Strand Scission
Burrows, C. J., & Muller, J. G. (1998) · Chemical Reviews · doi:10.1021/cr960421s · Cited by 1,736
Cited by
Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins
Lang, K., & Chin, J. W. (2014) · Chemical Reviews · doi:10.1021/cr400355w · Cited by 1,035
Metadata
- Authors
- Weisbrod, S. H., & Marx, A.
- Venue
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2008
- Issue
- 44
- Pages
- 5675
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W2144169173
- Cited by
- 211
- References
- 2
- FWCI
- 10.05
- Type
- journal article
- Language
- en
- Open access
- green
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- Weisbrod, S. H., & Marx, A. (2008). Novel strategies for the site-specific covalent labelling of nucleic acids. Chemical Communications. https://doi.org/10.1039/b809528k
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