Minding metals: Tailoring multifunctional chelating agents for neurodegenerative disease

Cited by (158)

Items 101–158 of 158

1. Insights into the Mechanisms of Amyloid Formation of ZnII-Ab11-28: pH-Dependent Zinc Coordination and Overall Charge as Key Parameters for Kinetics and the Structure of ZnII-Ab11-28 Aggregates
   Bruno Aliès, Giovanni La Penna, Stéphanie Sayen, Emmanuel Guillon, Christelle Hureau, Peter Faller · 2012 · Inorganic Chemistry
2. Unveiling the reaction mechanism of novel copper N -alkylated tetra-azacyclophanes with outstanding superoxide dismutase activity
   Álvaro Martínez‐Camarena, Pedro A. Sánchez‐Murcia, Salvador Blasco, Leticia González, Enrique García‐España · 2020 · Chemical Communications
3. Synthesis, Characterization, and Activity of a Triazine Bridged Antioxidant Small Molecule
   Paulina Gonzalez, Kristof Pota, Lara S. Turan, Viviana C. P. da Costa, Giridhar Rao Akkaraju, Kayla N. Green · 2017 · ACS Chemical Neuroscience
4. Synthesis of macrocyclic α-amino esters through the chemoselective hydrolysis of benzoxazinephanes
   Rodolfo Quevedo, Marlon González, Christian David Díaz‐Oviedo · 2012 · Tetrahedron Letters
5. Schiff base pyrazolone complexes of iron (III): synthesis, characterization, antimicrobial and antioxidant activity
   Kiran R. Surati, Pooja A. Sathe · 2016 · Medicinal Chemistry Research
6. FTIR and MS Evidence for Heavy Metal Binding to Anti-amyloidal NAP-Like Peptides
   Ancuța-Veronica Lupăescu, Monica Jureschi, Catalina Ionica Ciobanu, Laura Ion, Gheorghita N. Zbancioc, Brîndușa Alina Petre, Gabi Drochioiu · 2018 · International Journal of Peptide Research and Therapeutics
7. A Unified View of Assessing the Pro‐oxidant versus Antioxidant Nature of Amyloid Beta Conformers
   Suchitra Mitra, Pallavi Prasad, Saumen Chakraborty · 2018 · ChemBioChem
8. Insight into inhibition of the human amyloid beta protein precursor (APP: PDB ID 3UMI) using (E)-N-(pyridin-2-ylmethylene)arylamine (L R ) models: structure elucidation of a family of ZnX 2 -L R complexes
   Tushar S. Basu Baul, Sajal Kundu, Palwinder Singh, Shaveta Shaveta, Maria Fátima C. Guedes da Silva · 2014 · Dalton Transactions
9. A new triazine bearing a pyrazolone group capable of copper, nickel, and zinc chelation
   Akop Yepremyan, Arshad Mehmood, Samantha M. Brewer, Madalyn M. Barnett, Benjamin G. Janesko, Giridhar Rao Akkaraju, Eric E. Simanek, Kayla N. Green · 2018 · RSC Advances
10. Combining conformational sampling and selection to identify the binding mode of zinc-bound amyloid peptides with bifunctional molecules
    Liang Xu, Ke Gao, Chunyu Bao, Xicheng Wang · 2012 · Journal of Computer-Aided Molecular Design
11. Dual role of Cu2+ ions on the aggregation and degradation of soluble Aβ oligomers and protofibrils investigated by fluorescence spectroscopy and AFM
    Silvia Pérez García, Cristina Cuscó, Rosa F. Brissos, Ester Torrents, Amparo Caubet, Patrick Gámez · 2012 · Journal of Inorganic Biochemistry
12. Heavy metals toxicity on epigenetic modifications in the pathogenesis of Alzheimer's disease (AD)
    Dhivya Venkatesan, Sindduja Muthukumar, Mahalaxmi Iyer, Harysh Winster Suresh Babu, Abilash Valsala Gopalakrishnan, Mukesh Yadav, Balachandar Vellingiri · 2024 · Journal of Biochemical and Molecular Toxicology
13. Discovery of powerful multifaceted antioxidant for combating oxidative stress associated with neurodegenerative disorders
    Juhee Khan, Prabir Kumar Gharai, Shubham Garg, Sanju Gupta, Mohammad Umar Arshi, Rathnam Mallesh, Surajit Ghosh · 2025 · Acta Pharmaceutica Sinica B
14. C-Branched chiral (racemic) macrocyclic amino acids: structure of their Ni(ii), Zn(ii) and Cu(ii) complexes
    Daniel Pellico, Mar Gómez‐Gallego, Rosa Escudero, Pedro Ramírez‐López, Montserrat Oliván, Miguel Á. Sierra · 2011 · Dalton Transactions
15. A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress
    Andrew T. Franks, Qin Wang, Katherine J. Franz · 2015 · Bioorganic & Medicinal Chemistry Letters
16. Trehalose: A promising new treatment for traumatic brain injury? A systematic review of animal evidence
    Mohammad Ghorbani, Mohammad Ali Abouei Mehrizi, Mahboobeh Tajvidi, Mohmmad Amin Habibi, Mohammad Mohammadi, Saeid Esmaeilian, Paria Torabi, Elham Rahmanipour, Mahyar Daskareh, Aynaz Mohammadi · 2023 · Interdisciplinary Neurosurgery
17. In vitro assessment of chelating agents with regard to their abstraction efficiency of Cd2+ bound to plasma proteins
    Elham Zeini Jahromi, Jürgen Gailer · 2012 · Metallomics
18. Is iron associated with amyloid involved in the oxidative stress of Alzheimer's disease?
    Michel Nguyen, Meijie Huang, Yan Liu, Bernard Meunier, Anne Robert · 2017 · Comptes Rendus Chimie
19. Salpyran: A Cu(II) Selective Chelator with Therapeutic Potential
    Jack Devonport, Nikolett Bodnár, Andrew McGown, Mahmoud Bukar Maina, Louise C. Serpell, Csilla Kállay, John Spencer, George E. Κostakis · 2021 · Inorganic Chemistry
20. DpdtpA, A Multi-metal Ion Chelator, Attenuates Tau Phosphorylation and Microglial Inflammatory Response via Regulating the PI3K/AKT/GSK-3β Signal Pathways
    Lu Wang, Yingjuan Wei, Zhenzhou Sun, Lin‐Hua Jiang, Yaling Yin, Panpan Zheng, Yun Fu, Hongwei Wang, Changzheng Li, Jian‐Zhi Wang · 2023 · Neuroscience
21. Theoretical studies on the spectroscopic properties of a series of halide Zinc (II) complexes with pyridinylimine and pyridinylmethylamine derivatives
    Li Wang, Yanxin Zhang, Xiaohan Yu, Hongqing He, Jinglai Zhang · 2012 · Synthetic Metals
22. The hydrolytic susceptibility of prochelator BSIH in aqueous solutions
    Qin Wang, Katherine J. Franz · 2017 · Bioorganic & Medicinal Chemistry Letters
23. Synthesis and characterization of copper-specific tetradendate ligands as potential treatment for Alzheimer's disease
    Weixin Zhang, Meijie Huang, Christian Bijani, Yan Liu, Anne Robert, Bernard Meunier · 2018 · Comptes Rendus Chimie
24. Uses of Metal Compounds in Medicine
    Bernhard Lippert · 2013 · Elsevier eBooks
25. Thiol-Reactive Arylsulfonate Masks for Phenolate Donors in Antiproliferative Iron Prochelators
    Wangbin Wu, Yu‐Shien Sung, Elisa Tomat · 2022 · Inorganic Chemistry
26. Hydroxy- and aminomethylation reactions in the formation of oligomers from l-tyrosine and formaldehyde in basic medium
    Nelson Núñez-Dallos, Christian David Díaz‐Oviedo, Rodolfo Quevedo · 2014 · Tetrahedron Letters
27. Investigation of Some Metabolic Enzyme Inhibition Properties of Novel Chalcone‐Cu Complexes
    Rüstem Ebiri, Muhammet Turgut, Derya Aktaş Anıl, Yeliz Demir, Rüya Sağlamtaş, Mehmet Abdullah Alagöz, Öztekin Algül, Serdar Burmaoğlu · 2024 · ChemistrySelect
28. Evaluating the Multifunctionality of a New Modulator of Zinc-Induced Aβ Aggregation Using a Novel Computational Approach
    Mohsen Asadbegi, Amir Shamloo · 2021 · Journal of Chemical Information and Modeling
29. Sialic Acid Hydroxamate: A Potential Antioxidant and Inhibitor of Metal‐Induced β‐Amyloid Aggregates
    Rohan Yadav, Raghavendra Vasudeva Murthy, Raghavendra V Kikkeri · 2015 · ChemBioChem
30. Synthesis, physicochemical characterization and neuroprotective evaluation of novel 1-hydroxypyrazin-2(1 H )-one iron chelators in an in vitro cell model of Parkinson's disease
    Frank W. Lewis, Kathleen Bird, Jean-Philippe Navarro, Rawa El Fallah, Jérémy Brandel, Véronique Hubscher‐Bruder, Andrew Tsatsanis, James A. Duce, David Tétard, Samuel Bourne et al. · 2022 · Dalton Transactions
31. Development of new amphiphilic bio-organic assemblies for potential applications in iron-binding and targeting tumor cells
    Mindy M. Hugo, Ipsita A. Banerjee · 2018 · Soft Materials
32. The Chelating Abilities of Tertiary Amines with N-O-Donors Towards Cu(II) Ions and the Catalytic Properties of the Resulting Complexes
    Martina Zonzin, Martina Chianese, Andrea Squarcina, Degnet Melese Dereje, Ambra Campofelice, Alessia Da Fermo, Federica Belluti, Nadia Marino, Filip Dębicki, Aleksandra Kotynia et al. · 2025 · Molecules
33. Hybrid Antioxidant and Metal Sequestering Small Molecules Targeting the Molecular Features of Alzheimer’s Disease
    Kayla N. Green, Hannah M. Johnston, Marianne E. Burnett, Samantha M. Brewer · 2016 · Comments on Inorganic Chemistry
34. Alzheimer Hastalığı ve Anti-Alzheimer Etkili Bileşiklerin Yapılarının Araştırılması
    Ozden Tari, Ramazan YAĞMURTAŞAN · 2023 · Hacettepe University Journal of the Faculty of Pharmacy
35. Bioinorganic Neurochemistry
    Drew S. Folk, Filip Kielar, Katherine J. Franz · 2013 · Elsevier eBooks
36. Developing Ligands to Target Transition Metals in Cancer
    Rachel D. Utterback, Elisa Tomat · 2019 · Wiley eBooks
37. Ruthenium Complexes of Phenylbenzothiazole‐Quinoline based Ligands for Selective α‐Olefination of Methylazaarenes
    Surabhi Bhatt, Priyal Malpani, Swati Swornaprava Pati, Nitish Kumar, Nattamai S. P. Bhuvanesh, Hemant Joshi, Anuj K. Sharma · 2024 · European Journal of Inorganic Chemistry
38. High specificity is a key parameter for copper ligands as future therapeutic agents for Alzheimer’s, Wilson’s, and cancer diseases
    Anne Robert, Yan Liu, Michel Nguyen, Françoise Benoit‐Vical, Bernard Meunier · 2025 · Comptes Rendus Chimie
39. From Anti-Parkinson’s Drug Rasagiline to Novel Multitarget Iron Chelators with Acetylcholinesterase and Monoamine Oxidase Inhibitory and Neuroprotective Properties for Alzheimer’s Disease
    Hailin Zheng, Tamar Amit, Orit Bar‐Am, Mati Fridkin, Silvia A. Mandel, Moussa B. H. Youdim · 2022 · Springer eBooks
40. Synthesis and characterization of 8-aminoquinolines, substituted by electron donating groups, as high-affinity copper chelators for the treatment of Alzheimer's disease
    Ju Huang, M. Nguyen, Yan Liu, A. Robert, B. Meunier · 2019 · Comptes rendus. Chimie
41. From Anti-Parkinson’s Drug Rasagiline to Novel Multitarget Iron Chelators with Acetylcholinesterase and Monoamine Oxidase Inhibitory and Neuroprotective Properties for Alzheimer’s Disease
    Hailin Zheng, Tamar Amit, Orit Bar‐Am, Mati Fridkin, Silvia A. Mandel, Moussa B. H. Youdim · 2020 · Springer eBooks
42. Inhibition of nucleation and disruption of amyloid fibrillation in human lysozyme aggregation by a potent Cu(II) flufenamate chemotherapeutic drug candidate
    Huzaifa Yasir Khan, Yassir Hasan Khan, Md Nadir Hassan, Azeem Ahmad, Rizwan Hasan Khan, Farukh Arjmand · 2025 · Biophysical Chemistry
43. GC-MS Identification of Cholinesterase Inhibitory and Antioxidant Molecules from Leaves of Cnidoscolus aconitifolius (Miller) I.M. Johnston (Euphorbiaceae)
    JOEL OJOGBANE ONOJA, Ugwueze Nnamdi Joachin · 2022 · Current Enzyme Inhibition
44. Metallic Mysteries: Deciphering Their Contribution to Alzheimer’s Pathogenesis
    SA Kalwaghe, SS Sadar, Pradip Porwal, Shubhangi C. Daswadkar, NS Vyawahare · 2024 · International Journal of Pharmaceutical Sciences and Drug Research
45. An Overview of Multifunctional Metal Chelators as Potential Treatments for Neurodegenerative Diseases
    Frank W. Lewis, David Tétard · 2017 · Elsevier eBooks
46. 89Zr-Imuno-PET/111In-Imuno- SPECT: desenvolvimento radiofarmacêutico de agentes de imagem molecular para receptores EGF
    Raquel Benedetto · 2018
47. The role of alpha synuclein in Parkinson’s disease
    Dima Moualla · 2011 · The University of Bath Online Publications Store (The University of Bath)
48. Trace elements in human brain:age-related changes in diferent anatomical regions and changes related with neurodegenerative processes
    Patrícia Ramos · 2012 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
49. Metalloneurochemistry
    Geewoo Nam, Yelim Yi, Hyuck Jin Lee, Juri Lee, Juhye Kang, Mi Hee Lim · 2020 · Elsevier eBooks
50. Therapeutic Strategies to Combat the Onset and Progression of Neurological Diseases
    Robert R. Crichton, Roberta J. Ward · 2013 · Wiley eBooks
51. Synthesis and structural analysis of an asymmetric azacyclophane via Mannich cross macrocyclisation of -tyrosine derivatives
    Laura F. Leal, Sebastián Chaves, Rodolfo Quevedo · 2022 · Results in Chemistry
52. Development and Application of Analytical Strategies to Facilitate Protein-Ligand Binding Analysis on the Proteomic Scale
    Dongyu Wang · 2013 · DukeSpace (Duke University)
53. Nouvelles preuves de concept pour la chélatothérapie contre la maladie d'Alzheimer : études spectroscopiques des interactions entre les ions cuivre et zinc
    Amandine Conte‐Daban · 2017 · theses.fr (ABES)
54. Development of chelating materials for localized metal extraction in neurodegenerative diseases
    Juan Felipe Salazar Ariza · 2024 · theses.fr (ABES)
55. Rational drug design for Alzheimer’s disease: from approved therapies to next-generation clinical candidates and AI-guided innovation
    Sana Saffour, Turgut Seçkin Gül, Halise Inci Gul · 2026 · Future Medicinal Chemistry
56. BindingDB Entry 50002056: NOTA analogue: A first dithiocarbamate inhibitor of metallo-β-lactamases.
    BindingDB · 2020 · UC San Diego
57. BindingDB Entry 50047298: In silico to in vitro screening of hydroxypyridinones as acetylcholinesterase inhibitors.
    BindingDB · 2017 · UC San Diego
58. Metals and metal antagonists
    Joshua P. Gray, Sidhartha D. Ray · 2026 · Side effects of drugs annual