The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The direct catalytic asymmetric aldol reaction
Open accessAbstract
Asymmetric aldol reactions are a powerful method for the construction of carbon-carbon bonds in an enantioselective fashion. Historically this reaction has been performed in a stoichiometric fashion to control the various aspects of chemo-, diastereo-, regio- and enantioselectivity, however, a more atom economical approach would unite high selectivity with the use of only a catalytic amount of a chiral promoter. This critical review documents the development of direct catalytic asymmetric aldol methodologies, including organocatalytic and metal-based strategies. New methods have improved the reactivity, selectivity and substrate scope of the direct aldol reaction and enabled the synthesis of complex molecular targets (357 references).
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Citations
Cites
Thermodynamic control of asymmetric amplification in amino acid catalysis
Klussmann, M., Iwamura, H., Mathew, S. P., Wells, D. H., Pandya, U., Armstrong, A., & Blackmond, D. G. (2006) · Nature · doi:10.1038/nature04780 · Cited by 396
Plausible origins of homochirality in the amino acid catalyzed neogenesis of carbohydrates
Córdova, A., Engqvist, M., Ibrahem, I., Casas, J., & Sundén, H. (2005) · Chem. Commun. · doi:10.1039/b500589b · Cited by 127
Metadata
- Authors
- Trost, B. M., & Brindle, C. S.
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 39
- Issue
- 5
- Pages
- 1600
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W1971996425
- Cited by
- 750
- References
- 2
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- green
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- Trost, B. M., & Brindle, C. S. (2010). The direct catalytic asymmetric aldol reaction. Chemical Society Reviews. https://doi.org/10.1039/b923537j
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