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Heterogeneous catalytic synthesis using microreactor technology
Abstract
The application of heterogeneous catalysis in conjunction with microreactor technology can facilitate a cleaner and scalable flow methodology for organic synthesis. In this tutorial review we present recent advances in the design of supported catalysts for emerging synthetic applications within microreactor technology. Specifically, transition metal catalysts such as palladium, copper, ruthenium, and nickel are described on silica, monolithic, magnetic nanoparticles and polymer supports. These catalysts have been utilised to promote a range of reactions including Heck, Sonogashira, Suzuki, Kumada, olefin metathesis, hydrogenation and benzannulation reactions.
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Cited by
The Hitchhiker’s Guide to Flow Chemistry
Plutschack, M. B., Pieber, B., Gilmore, K., & Seeberger, P. H. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00183 · Cited by 1,995
Continuous flow reactors: a perspective
Wiles, C., & Watts, P. (2012) · Green Chem. · doi:10.1039/c1gc16022b · Cited by 626
Metadata
- Authors
- Frost, C. G., & Mutton, L.
- Venue
- Green Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 12
- Issue
- 10
- Pages
- 1687
- ISSN
- 1463-9262 (ISSN-L)
- 1463-9270
- OpenAlex
- W2094886308
- Cited by
- 292
- References
- 0
- FWCI
- 16.20
- Type
- journal article
- Language
- en
- Open access
- closed
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