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Cited by 1,476

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Decarboxylative coupling reactions: a modern strategy for C–C-bond formation

Rodríguez, Nuria, Goossen, Lukas J.·2011·Chemical Society Reviews

Abstract

This critical review examines transition metal-catalyzed decarboxylative couplings that have emerged within recent years as a powerful strategy to form carbon-carbon or carbon-heteroatom bonds starting from carboxylic acids. In these reactions, C-C bonds to carboxylate groups are cleaved, and in their place, new carbon-carbon bonds are formed. Decarboxylative cross-couplings constitute advantageous alternatives to traditional cross-coupling or addition reactions involving preformed organometallic reagents. Decarboxylative reaction variants are also known for Heck reactions, direct arylation processes, and carbon-heteroatom bond forming reactions.

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Metadata

Authors
Rodríguez, N., & Goossen, L. J.
Venue
Chemical Society Reviews
Published
2011
Volume
40
Issue
10
Pages
5030
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
OpenAlex
W2012413753
Cited by
1,476
References
3
FWCI
2.09
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Decarboxylative coupling reactions: a modern strategy for C–C-bond formation. https://app.cochat.ai/papers/10.1039/c1cs15093f
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Rodríguez, N., & Goossen, L. J. (2011). Decarboxylative coupling reactions: a modern strategy for C–C-bond formation. Chemical Society Reviews. https://doi.org/10.1039/c1cs15093f

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.