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Efficient synthesis of 3,4-dihydropyrimidin-2-ones in low melting tartaric acid–urea mixtures
Open accessAbstract
A general, efficient and green method for the synthesis of dihydropyrimidinones is described under mild conditions employing low melting mixtures of L-(+)-tartaric acid and urea derivatives as a novel reaction medium. The melt plays a triple role: as solvent, as catalyst and as reactant, furnishing highly functionalized dihydropyrimidinones in good to excellent yields.
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Cited by
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Natural deep eutectic solvents as new potential media for green technology
Dai, Y., van Spronsen, J., Witkamp, G.-J., Verpoorte, R., & Choi, Y. H. (2013) · Analytica Chimica Acta · doi:10.1016/j.aca.2012.12.019 · Cited by 2,694
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Alonso, D. A., Baeza, A., Chinchilla, R., Guillena, G., Pastor, I. M., & Ramón, D. J. (2016) · European Journal of Organic Chemistry · doi:10.1002/ejoc.201501197 · Cited by 709
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Metadata
- Authors
- Gore, S., Baskaran, S., & Koenig, B.
- Venue
- Green Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2011
- Volume
- 13
- Issue
- 4
- Pages
- 1009
- ISSN
- 1463-9262 (ISSN-L)
- 1463-9270
- OpenAlex
- W2122033201
- Cited by
- 210
- References
- 0
- FWCI
- 6.43
- Type
- journal article
- Language
- en
- Open access
- green
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- Gore, S., Baskaran, S., & Koenig, B. (2011). Efficient synthesis of 3,4-dihydropyrimidin-2-ones in low melting tartaric acid–urea mixtures. Green Chemistry. https://doi.org/10.1039/c1gc00009h
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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