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Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors
Abstract
A large-area, continuous, few-layer reduced graphene oxide (rGO) thin film has been fabricated on a Si/SiO(2) wafer using the Langmuir-Blodgett (LB) method followed by thermal reduction. After photochemical reduction of Pt nanoparticles (PtNPs) on rGO, the obtained PtNPs/rGO composite is employed as the conductive channel in a solution-gated field effect transistor (FET), which is then used for real-time detection of hybridization of single-stranded DNA (ssDNA) with high sensitivity (2.4 nM). Such a simple, but effective method for fabrication of rGO-based transistors shows great potential for mass-production of graphene-based electronic biosensors.
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Cited by
Nano-graphene in biomedicine: theranostic applications
Yang, K., Feng, L., Shi, X., & Liu, Z. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35342c · Cited by 1,634
Graphene-based nanomaterials for drug delivery and tissue engineering
Goenka, S., Sant, V., & Sant, S. (2014) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.10.017 · Cited by 1,311
Synthesis and applications of graphene-based noble metal nanostructures
Tan, C., Huang, X., & Zhang, H. (2013) · Materials Today · doi:10.1016/j.mattod.2013.01.021 · Cited by 286
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Metadata
- Authors
- Yin, Z., He, Q., Huang, X., Zhang, J., Wu, S., Chen, P., Lu, G., Chen, P., Zhang, Q., Yan, Q., & Zhang, H.
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2012
- Volume
- 4
- Issue
- 1
- Pages
- 293-297
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- OpenAlex
- W2141891521
- Cited by
- 195
- References
- 0
- FWCI
- 13.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yin, Z., He, Q., Huang, X., Zhang, J., Wu, S., Chen, P., Lu, G., Chen, P., Zhang, Q., Yan, Q., & Zhang, H. (2012). Real-time DNA detection using Pt nanoparticle-decorated reduced graphene oxide field-effect transistors. Nanoscale. https://doi.org/10.1039/c1nr11149c
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