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Cited by 165

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New avenues in the design and potential application of metal complexes for photodynamic therapy

Stacey, Oliver J., Pope, Simon J. A.·2013·RSC Advances

Abstract

Photodynamic therapy (PDT) requires a photosensitizing agent, which can undergo visible light activation, yielding reactive oxygen species and/or radical species. The key physical properties and desirable attributes of established PDT photosensitizer agents are discussed, together with a consideration of the role that photoactive metal coordination complexes may have in the future design of such agents. A number of classes of metal complex are included with a focus upon their ability to generate singlet oxygen, and prior indications of biological utility, compatibility and cytotoxicity through cellular imaging work and DNA binding behaviour.

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Metadata

Authors
Stacey, O. J., & Pope, S. J. A.
Venue
RSC Advances
Published
2013
Volume
3
Issue
48
Pages
25550
ISSN
2046-2069 (ISSN-L)
OpenAlex
W2085614137
Cited by
165
References
1
FWCI
7.55
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: New avenues in the design and potential application of metal complexes for photodynamic therapy. https://app.cochat.ai/papers/10.1039/c3ra45219k
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Stacey, O. J., & Pope, S. J. A. (2013). New avenues in the design and potential application of metal complexes for photodynamic therapy. RSC Advances. https://doi.org/10.1039/c3ra45219k

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.