High levels of Bifidobacteria are associated with increased levels of anthocyanin microbial metabolites: a randomized clinical trial
Open accessAbstract
The health benefits associated with the consumption of polyphenol-rich foods have been studied in depth, however, the full mechanism of action remains unknown.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In vitro and in vivo studies have shown that modulating bifidobacterial levels through probiotic or prebiotic supplementation can change the overall composition and metabolism of the gut microbiota.
“In vitro and in vivo studies have shown that modulating bifidobacterial levels through probiotic or prebiotic supplementation can change the overall composition and metabolism of the gut microbiota (49–53).”
From Bifidobacteria and Their Health-Promoting Effects (2017) · cites this paper as [50]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 46 · Cited by 154
Research works printed but not linked: 43
- W. C. Willett, Science, 1994, 264, 532-537.
- M. H. Traka and R. F. Mithen, Plant Cell, 2011, 23, 2483- 2497.
- T. E. Sweeney and J. M. Morton, JAMA Surg., 2013, 148, 563- 569.
- P. Kovatcheva-Datchary and T. Arora, Best Pract. Res., Clin. Gastroenterol., 2013, 27, 59-72.
- I. M. Carroll, D. W. Threadgill and D. S. Threadgill, Mamm. Genome, 2009, 20, 395-403.
- M. I. Queipo-Ortuno, M. Boto-Ordonez, M. Murri, J. M. Gomez-Zumaquero, M. Clemente-Postigo, R. Estruch, F. Cardona Diaz, C. Andres-Lacueva and F. J. Tinahones, Am. J. Clin. Nutr., 2012, 95, 1323-1334.
- X. Tzounis, A. Rodriguez-Mateos, J. Vulevic, G. R. Gibson, C. Kwik-Uribe and J. P. Spencer, Am. J. Clin. Nutr., 2011, 93, 62-72.
- J. van Duynhoven, E. E. Vaughan, D. M. Jacobs, R. A. Kemperman, E. J. van Velzen, G. Gross, L. C. Roger, S. Possemiers, A. K. Smilde, J. Dore, J. A. Westerhuis and T. Van de Wiele, Proc. Natl. Acad. Sci. U. S. A., 2011, 108(suppl. 1), 4531-4538.
- J. C. Espin, M. Larrosa, M. T. Garcia-Conesa and F. Tomas- Barberan, J. Evidence-Based Complementary Altern. Med., 2013, 2013, 270418.
- M. V. Selma, J. C. Espin and F. A. Tomas-Barberan, J. Agric. Food Chem., 2009, 57, 6485-6501.
- T. Requena, M. Monagas, M. A. Pozo-Bayón, P. J. Martín- Álvarez, B. Bartolomé, R. del Campo, M. Ávila, M. C. Martínez-Cuesta, C. Peláez and M. V. Moreno- Arribas, Trends Food Sci. Technol., 2010, 21, 332-344.
- M. Monagas, M. Urpi-Sarda, F. Sanchez-Patan, R. Llorach, I. Garrido, C. Gomez-Cordoves, C. Andres-Lacueva and B. Bartolome, Food Funct., 2010, 1, 233-253.
- M. Boto-Ordonez, M. Urpi-Sarda, M. I. Queipo-Ortuño, D. Corella, F. J. Tinahones, R. Estruch and C. Andres- Lacueva, J. Agric. Food Chem., 2013, 61, 9166-9175.
- M. Boto-Ordonez, J. A. Rothwell, C. Andres-Lacueva, C. Manach, A. Scalbert and M. Urpi-Sarda, Mol. Nutr. Food Res., 2013, 58, 466-477.
- F. Sanchez-Patan, C. Cueva, M. Monagas, G. E. Walton, G. R. Gibson, J. E. Quintanilla-Lopez, R. Lebron-Aguilar, P. J. Martin-Alvarez, M. V. Moreno-Arribas and B. Bartolome, J. Agric. Food Chem., 2012, 60, 2136-2147.
- R. Kemperman, G. Gross, S. Mondot, S. Possemiers, M. Marzorati, T. Van de Wiele, J. Dore and E. E. Vaughan, Food Res. Int., 2013, 53, 659-669.
- M. Urpi-Sarda, M. Monagas, N. Khan, R. Llorach, R. M. Lamuela-Raventos, O. Jauregui, R. Estruch, M. Izquierdo-Pulido and C. Andres-Lacueva, J. Chromatogr. A, 2009, 1216, 7258-7267.
- M. Urpi-Sarda, M. Monagas, N. Khan, R. M. Lamuela- Raventos, C. Santos-Buelga, E. Sacanella, M. Castell, J. Permanyer and C. Andres-Lacueva, Anal. Bioanal. Chem., 2009, 394, 1545-1556.
- J. Xia, N. Psychogios, N. Young and D. S. Wishart, Nucleic Acids Res., 2009, 37, W652-W660.
- X. He, M. L. Marco and C. M. Slupsky, J. Agric. Food Chem., 2013, 61, 9559-9574.
- M. I. Queipo-Ortuno, L. M. Seoane, M. Murri, M. Pardo, J. M. Gomez-Zumaquero, F. Cardona, F. Casanueva and F. J. Tinahones, PLoS One, 2013, 8, e65465.
- M. Arumugam, J. Raes, E. Pelletier, D. Le Paslier, T. Yamada, D. R. Mende, G. R. Fernandes, J. Tap, T. Bruls, J. M. Batto, M. Bertalan, N. Borruel, F. Casellas, L. Fernandez, L. Gautier, T. Hansen, M. Hattori, T. Hayashi, M. Kleerebezem, K. Kurokawa, M. Leclerc, F. Levenez, C. Manichanh, H. B. Nielsen, T. Nielsen, N. Pons, J. Poulain, J. Qin, T. Sicheritz-Ponten, S. Tims, D. Torrents, E. Ugarte, E. G. Zoetendal, J. Wang, F. Guarner, O. Pedersen, W. M. de Vos, S. Brunak, J. Dore, M. Antolin, F. Artiguenave, H. M. Blottiere, M. Almeida, C. Brechot, C. Cara, C. Chervaux, A. Cultrone, C. Delorme, G. Denariaz, R. Dervyn, K. U. Foerstner, C. Friss, M. van de Guchte, E. Guedon, F. Haimet, W. Huber, J. van Hylckama- Vlieg, A. Jamet, C. Juste, G. Kaci, J. Knol, O. Lakhdari, S. Layec, K. Le Roux, E. Maguin, A. Merieux, R. Melo Minardi, C. M'Rini, J. Muller, R. Oozeer, J. Parkhill, P. Renault, M. Rescigno, N. Sanchez, S. Sunagawa, A. Torrejon, K. Turner, G. Vandemeulebrouck, E. Varela, Y. Winogradsky, G. Zeller, J. Weissenbach, S. D. Ehrlich and P. Bork, Nature, 2011, 473, 174-180.
- A. Bub, B. Watzl, D. Heeb, G. Rechkemmer and K. Briviba, Eur. J. Nutr., 2001, 40, 113-120.
- C. Czank, A. Cassidy, Q. Zhang, D. J. Morrison, T. Preston, P. A. Kroon, N. P. Botting and C. D. Kay, Am. J. Clin. Nutr., 2013, 97, 995-1003.
- M. Ávila, M. Hidalgo, C. Sánchez-Moreno, C. Pelaez, T. Requena and S. D. Pascual-Teresa, Food Res. Int., 2009, 42, 1453-1461.
- L. Roncaglia, A. Amaretti, S. Raimondi, A. Leonardi and M. Rossi, Appl. Microbiol. Biotechnol., 2011, 92, 159-168.
- G. M. Woodward, P. W. Needs and C. D. Kay, Mol. Nutr. Food Res., 2011, 55, 378-386.
- A. Sachan, S. Ghosh, S. K. Sen and A. Mitra, Appl. Microbiol. Biotechnol., 2006, 71, 720-727.
- M. P. Gonthier, V. Cheynier, J. L. Donovan, C. Manach, C. Morand, I. Mila, C. Lapierre, C. Remesy and A. Scalbert, J. Nutr., 2003, 133, 461-467.
- M. Hidalgo, M. J. Oruna-Concha, S. Kolida, G. E. Walton, S. Kallithraka, J. P. Spencer and S. de Pascual-Teresa, J. Agric. Food Chem., 2012, 60, 3882-3890.
- T. Nurmi, J. Mursu, M. Heinonen, A. Nurmi, R. Hiltunen and S. Voutilainen, J. Agric. Food Chem., 2009, 57, 2274-2281.
- A. Nurmi, T. Nurmi, J. Mursu, R. Hiltunen and S. Voutilainen, J. Agric. Food Chem., 2006, 54, 6916-6923.
- S. Guglielmetti, D. Fracassetti, V. Taverniti, C. Del Bo, S. Vendrame, D. Klimis-Zacas, S. Arioli, P. Riso and M. Porrini, J. Agric. Food Chem., 2013, 61, 8134-8140.
- H. M. An, S. Y. Park, K. Lee do, J. R. Kim, M. K. Cha, S. W. Lee, H. T. Lim, K. J. Kim and N. J. Ha, Lipids Health Dis., 2011, 10, 116.
- D. I. Pereira and G. R. Gibson, Appl. Environ. Microbiol., 2002, 68, 4689-4693.
- T. Tsuda, Y. Kato and T. Osawa, FEBS Lett., 2000, 484, 207- 210.
- T. Simoncini, E. Lenzi, A. Zochling, S. Gopal, L. Goglia, E. Russo, K. Polak, E. Casarosa, A. Jungbauer, A. D. Genazzani and A. R. Genazzani, Maturitas, 2011, 70, 169-175.
- M. Hidalgo, S. Martin-Santamaria, I. Recio, C. Sanchez- Moreno, B. de Pascual-Teresa, G. Rimbach and S. de Pascual-Teresa, Genes Nutr., 2012, 7, 295-306.
- M. Clemente-Postigo, M. I. Queipo-Ortuno, M. Boto- Ordonez, L. Coin-Araguez, M. M. Roca-Rodriguez, J. Delgado-Lista, F. Cardona, C. Andres-Lacueva and F. J. Tinahones, Am. J. Clin. Nutr., 2013, 97, 1053-1061.
- C. M. Jung, T. M. Heinze, L. K. Schnackenberg, L. B. Mullis, S. A. Elkins, C. A. Elkins, R. S. Steele and J. B. Sutherland, FEMS Microbiol. Lett., 2009, 297, 266-273.
- H. C. Lee, A. M. Jenner, C. S. Low and Y. K. Lee, Res. Microbiol., 2006, 157, 876-884.
- G. Özkan, O. Sagdiç, N. Göktürk Baydar and Z. Kurumahmutoglu, J. Sci. Food Agric., 2004, 84, 1807-1811.
- R. Puupponen-Pimia, L. Nohynek, C. Meier, M. Kahkonen, M. Heinonen, A. Hopia and K. M. Oksman-Caldentey, J. Appl. Microbiol., 2001, 90, 494-507.
- Authors
- Boto-Ordóñez, M., Urpi-Sarda, M., Queipo-Ortuño, M. I., Tulipani, S., Tinahones, F. J., & Andres-Lacueva, C.
- Affiliations
- Biomarkers and Nutritional & Food Metabolomics Research Group
- Research Laboratory
- Institut National des Sciences Appliquées de Lyon (FR)
- Instituto de Salud Carlos III (ES)
- Venue
- Food Funct.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2014
- Volume
- 5
- Issue
- 8
- Pages
- 1932-1938
- ISSN
- 2042-6496 (ISSN-L)
- 2042-650X
- OpenAlex
- W2048592243
- Cited by
- 154
- References
- 46
- Citations by year
- 2026: 8 · 2025: 17 · 2024: 10 · 2023: 15 · 2022: 17 · 2021: 17 · 2020: 19 · 2019: 12 · 2018: 15 · 2017: 8 · 2016: 9 · 2015: 7
- FWCI
- 3.28
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Food & Function (publishedVersion)
- PubMed (publishedVersion)
- RECERCAT (Consorci de Serveis Universitaris de Catalunya) (publishedVersion)
- Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona) (submittedVersion, public-domain)
- RISalud Institutional Health Repository of Andalucía (submittedVersion, other-oa)
- Funders
- Ministerio de Economía y Competitividad (AGL2009-13906-C02-01, CSD2007-063)
- Ministerio de Ciencia e Innovación (CSD2007-063)
- Instituto de Salud Carlos III (CP13/00065)
- European Social Fund
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Agricultural and Biological Sciences › Food Science › Fermentation and Sensory Analysis
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Keywords
- Bifidobacterium, anthocyanin metabolites, gut microbiota, red wine, polyphenols, syringic acid, p-hydroxybenzoic acid, Enterococcus, Eggerthella lenta, prebiotics, probiotics
- MeSH terms
- Alcoholic Beverages, Anthocyanins, Bifidobacterium, Chromatography, Liquid, Coumaric Acids, Feces, Gallic Acid, Humans, Male, Middle Aged, Parabens, Propionates, Wine, Enterococcus, Cross-Over Studies, Tandem Mass Spectrometry, Polyphenols
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review