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Gold nanoparticle-decorated MoS2 nanosheets for simultaneous detection of ascorbic acid, dopamine and uric acid

Open access
Sun, Haofan, Chao, Jie, Zuo, Xiaolei, Su, Shao, Liu, Xingfen, Yuwen, Lihui, Fan, Chunhai, Wang, Lianhui·2014·RSC Advances

Abstract

An electrochemical sensor has been developed for simultaneous detection of dopamine (DA), uric acid (UA) and ascorbic acid (AA) based on a gold nanoparticle-decorated MoS2 nanocomposite (AuNPs@MoS2) modified electrode. The AuNPs@MoS2 nanocomposite has been synthesized by electrodeposition of AuNPs on the MoS2 nanosheets, which possesses better properties than pure AuNPs and MoS2. The AuNPs@MoS2 film modified electrode showed excellent electrocatalytic activity toward the oxidation of AA, DA and UA with three well-resolved oxidation peaks. The peak separation of AA–DA, DA–UA and AA–UA is 151 mV, 137 mV and 288 mV, respectively, which permits the modified electrode to individually or simultaneously analyze AA, DA and UA by differential pulse voltammetry (DPV). Under optimum conditions, the AuNPs@MoS2 modified electrode exhibits linear response toward AA, DA and UA in the range of 50–100 000 μM, 0.05–30 μM and 50–40 000 μM, respectively. Moreover, the MoS2-based modified electrode was successfully employed to determine DA in human serum samples with satisfactory results.

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Metadata

Authors
Sun, H., Chao, J., Zuo, X., Su, S., Liu, X., Yuwen, L., Fan, C., & Wang, L.
Venue
RSC Advances
Published
2014
Volume
4
Issue
52
Pages
27625
ISSN
2046-2069 (ISSN-L)
OpenAlex
W1984246872
Cited by
240
References
0
FWCI
12.73
Type
journal article
Language
en
Open access
bronze

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Sun, H., Chao, J., Zuo, X., Su, S., Liu, X., Yuwen, L., Fan, C., & Wang, L. (2014). Gold nanoparticle-decorated MoS2 nanosheets for simultaneous detection of ascorbic acid, dopamine and uric acid. RSC Advances. https://doi.org/10.1039/c4ra04046e

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