A7RC peptide modified paclitaxel liposomes dually target breast cancer
Abstract
A7RC enhanced the accumulation of paclitaxel liposomes in a neuropilin-1 high expressing breast cancer mouse model and inhibited tumor growth and angiogenesis.
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Liposomes conjugated with paclitaxel and A7R peptide inhibited tumor growth and angiogenesis simultaneously.
“Liposomes conjugated with paclitaxel and A7R peptide inhibited tumor growth and angiogenesis simultaneously.240”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [240]
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References 59 · Cited by 93
- Authors
- Cao, J., Wang, R., Gao, N., Li, M., Tian, X., Yang, W., Ruan, Y., Zhou, C., Wang, G., Liu, X., Tang, S., Yu, Y., Liu, Y., Sun, G., Peng, H., & Wang, Q.
- Affiliations
- Harbin Medical University (CN)
- Iowa State University (US)
- Corresponding author
- Peng, Haisheng
- Wang, Qun
- ORCID
- Venue
- Biomaterials Science
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2015
- Volume
- 3
- Issue
- 12
- Pages
- 1545-1554
- ISSN
- 2047-4830 (ISSN-L)
- 2047-4849
- OpenAlex
- W1740419624
- Cited by
- 93
- References
- 59
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 7 · 2023: 5 · 2022: 9 · 2021: 10 · 2020: 7 · 2019: 14 · 2018: 8 · 2017: 15 · 2016: 11 · 2014: 1
- FWCI
- 4.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biomaterials Science (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Interference and Gene Delivery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Angiogenesis and VEGF in Cancer
- Keywords
- paclitaxel liposome, breast cancer, tumor angiogenesis inhibition, targeted drug delivery, MDA-MB-231 cells, liposome internalization, drug carriers
- MeSH terms
- Antineoplastic Agents, Breast Neoplasms, Collagen, Drug Combinations, Female, Humans, Laminin, Ligands, Liposomes, Oligopeptides, Proteoglycans, Drug Delivery Systems, Paclitaxel, Xenograft Model Antitumor Assays, Cell Line, Tumor
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