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Cited by 121Analytical Chemistry and ChromatographyChemistry and Stereochemistry StudiesMolecular spectroscopy and chirality

The self-disproportionation of enantiomers (SDE): a menace or an opportunity?

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Han, Jianlin, Kitagawa, Osamu, Wzorek, Alicja, Klika, Karel D., Soloshonok, Vadim A.·2018·Chemical Science
DOI 10.1039/c7sc05138gPMC PMC5892310
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Abstract

Herein we report on the well-documented, yet not widely known, phenomenon of the self-disproportionation of enantiomers (SDE): the spontaneous fractionation of scalemic material into enantioenriched and -depleted fractions when any physicochemical process is applied.

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  • Some mechanisms are known for increasing an existing enantiomeric excess, such as self-disproportionation of enantiomers, non-linear effects in asymmetric catalysis, and stereoselective polymerization.

    “Some mechanisms are known for increasing an existing e.e., such as the self-disproportionation of enantiomers (SDE), 61 non-linear effects in asymmetric catalysis, 62,63 and stereoselective polymerization.64”

    From Possible chemical and physical scenarios towards biological homochirality (2022) · cites this paper as [61]

  • Self-disproportionation of enantiomers (SDE) is not rare for organic molecules and may occur through a wide range of physicochemical processes.

    “This phenomenon of self-disproportionation of the enantiomers (SDE) is not rare for organic molecules and may occur through a wide range of physicochemical processes.61”

    From Possible chemical and physical scenarios towards biological homochirality (2022) · cites this paper as [61]

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Authors
Han, J., Kitagawa, O., Wzorek, A., Klika, K. D., & Soloshonok, V. A.
Affiliations
  • Nanjing University (CN)
  • Shibaura Institute of Technology (JP)
  • Jan Kochanowski University (PL)
  • German Cancer Research Center (DE)
  • Ikerbasque (ES)
Corresponding author
  • Han, Jianlin
  • Klika, Karel D.
  • Soloshonok, Vadim A.
ORCID
Venue
Chemical Science
Publisher
Royal Society of Chemistry (RSC)
Published
2018
Volume
9
Issue
7
Pages
1718-1739
ISSN
  • 2041-6520 (ISSN-L)
  • 2041-6539
DOI
10.1039/c7sc05138g
PMC
PMC5892310
OpenAlex
W2784286141
Cited by
121
References
7
Citations by year
2026: 8 · 2025: 7 · 2024: 11 · 2023: 20 · 2022: 14 · 2021: 20 · 2020: 13 · 2019: 18 · 2018: 10
FWCI
1.92
Type
journal article
Language
en
Open access
Licence
Locations
  • Chemical Science (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (21102071, 21472082)
  • Japan Society for the Promotion of Science (C 17K08220)
  • Ministry of Science and Higher Education (612 561)
  • Ikerbasque, Basque Foundation for Science
Topics
  • Physical Sciences › Chemistry › Spectroscopy › Analytical Chemistry and Chromatography
  • Physical Sciences › Chemistry › Organic Chemistry › Chemistry and Stereochemistry Studies
  • Physical Sciences › Chemistry › Spectroscopy › Molecular spectroscopy and chirality
Keywords
asymmetric catalysis, halogen bonding, hydrogen bonding, chiral selectors, racemic resolution

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