J-Aggregate squaraine nanoparticles with bright NIR-II fluorescence for imaging guided photothermal therapy
Abstract
J-aggregate nanoparticles (SQP-NPs (J) ) were prepared for bright NIR-II fluorescence imaging guided photothermal therapy of cancer.
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Squaraine-based nanoparticles with bright fluorescence near 1100 nm have been used for SWIR imaging-guided photothermal therapy on MCF-7 tumor-bearing mice.
“Squaraine-based nanoparticles with bright fluorescence near 1100 nm have been used for SWIR imaging-guided phototermal therapy on MCF-7 (Michigan Cancer Foundation-7) tumor-bearing mice (Figure 4e).116”
From The Pursuit of Shortwave Infrared-Emitting Nanoparticles with Bright Fluorescence through Molecular Design and Excited-State Engineering of Molecular Aggregates (2022) · cites this paper as [116]
Particles exhibiting J-type interaction of squaraine dye coprecipitated with an amphiphilic copolymer (PEG-b-PPG-b-PEG, Pluronic-127) formed stable spherical-shaped particles with a diameter of 82 nm, large ε (εmax ≈ 0.5 × 10^5 M-1 cm-1), small Stokes shift (10 nm), and Φfl of 0.0545%.
“Particles exhibiting J-type interaction of squaraine dye coprecipitated with an amphiphilic copolymer (PEG-b-PPG-b-PEG, Pluronic-127; PEG = poly(ethylene glycol)) formed stable spherical-shaped particles with a diameter of 82 nm, large ε (εmax ≈ 0.5 × 105 M–1 cm–1), small Stokes shift (10 nm), and Φfl of 0.0545%.”
From The Pursuit of Shortwave Infrared-Emitting Nanoparticles with Bright Fluorescence through Molecular Design and Excited-State Engineering of Molecular Aggregates (2022) · cites this paper as [116]
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References 25 · Cited by 167
- Authors
- Sun, P., Wu, Q., Sun, X., Miao, H., Deng, W., Zhang, W., Fan, Q., & Huang, W.
- Affiliations
- Nanjing University of Posts and Telecommunications (CN)
- Georgia Institute of Technology (US)
- Northwestern Polytechnical University (CN)
- Corresponding author
- Fan, Quli
- Venue
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2018
- Volume
- 54
- Issue
- 95
- Pages
- 13395-13398
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W2899633643
- Cited by
- 167
- References
- 25
- Citations by year
- 2026: 11 · 2025: 8 · 2024: 22 · 2023: 20 · 2022: 24 · 2021: 33 · 2020: 38 · 2019: 11
- FWCI
- 7.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Communications (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (21574064, 21604042, 21674048)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Photochemistry and Electron Transfer Studies
- Keywords
- squaraine, NIR-II fluorescence, second near-infrared window, photothermal therapy, image-guided therapy, fluorescence enhancement, H-aggregates, MCF-7 breast cancer, tumor imaging
- MeSH terms
- Animals, Cyclobutanes, Female, Fluorescence, Fluorescent Dyes, Humans, Infrared Rays, Injections, Intravenous, Mammary Neoplasms, Experimental, Mice, Inbred BALB C, Phenols, Phototherapy, Molecular Structure, Mice, Nanoparticles, MCF-7 Cells
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