Cited by 36Pancreatic function and diabetesTissue Engineering and Regenerative Medicine3D Printing in Biomedical Research

Bioengineering a pre-vascularized pouch for subsequent islet transplantation using VEGF-loaded polylactide capsules

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Kasoju, Naresh, Pátíková, Alžběta, Wawrzynska, Edyta, Vojtíšková, Alžběta, Sedlačík, Tomáš, Kumorek, Marta, Pop-Georgievski, Ognen, Sticová, Eva +2 more·2020·Biomaterials Science

Abstract

The effectiveness of cell transplantation can be improved by optimization of the transplantation site.

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  • Incorporating VEGF-releasing capsules into a pre-vascularization strategy or transplanting islets within VEGF-releasing hydrogels further improved vessel formation.

    “Incorporating vascular endothelial growth factor (VEGF)-releasing capsules into a similar pre-vascularization strategy152 or transplanting islets within VEGF-releasing hydrogels153 were shown to further improve vessel formation.”

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Authors
Kasoju, N., Pátíková, A., Wawrzynska, E., Vojtíšková, A., Sedlačík, T., Kumorek, M., Pop-Georgievski, O., Sticová, E., Kříž, J., & Kubies, D.
Affiliations
  • Czech Academy of Sciences (CZ)
  • Institute of Clinical and Experimental Medicine (CZ)
  • Institute of Macromolecular Chemistry Czech Academy of Sciences
  • Charles University (CZ)
Corresponding author
  • Kříž, Jan
  • Kubies, Dana
Venue
Biomaterials Science
Published
2020
Volume
8
Issue
2
Pages
631-647
ISSN
  • 2047-4830 (ISSN-L)
  • 2047-4849
OpenAlex
W2983223004
Cited by
36
References
57
Citations by year
2026: 1 · 2025: 3 · 2024: 10 · 2023: 7 · 2022: 4 · 2021: 8 · 2020: 3
FWCI
3.58
Type
journal article
Language
en
Open access
Locations
  • Biomaterials Science (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Funders
  • Agentura Pro Zdravotnický Výzkum České Republiky (16-28254A)
  • Ministerstvo Školství, Mládeže a Tělovýchovy (BIOCEV-FAR LQ1604, CZ.1.05/ 1.1.00/02.0109)
  • Ministerstvo Zdravotnictví Ceské Republiky (IN00023001)
  • Univerzita Karlova v Praze (100217)
Topics
  • Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
  • Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
  • Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
Keywords
islet transplantation, vascular endothelial growth factor, vascularization, bioengineered tissue
MeSH terms
Animals, Blood Glucose, Capsules, Diabetes Mellitus, Experimental, Injections, Intraperitoneal, Male, Particle Size, Polyesters, Rats, Inbred Lew, Streptozocin, Molecular Structure, Islets of Langerhans Transplantation, Neovascularization, Physiologic, Vascular Endothelial Growth Factors, Rats, Bioengineering

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