Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens
Open accessAbstract
Mitochondria-targeted photosensitizers with highly efficient singlet oxygen generation, bright near-infrared AIE and good two-photon absorption are obtained through ingenious molecular engineering for cancer cell-selective photodynamic therapy.
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References 63 · Cited by 172
Research works printed but not linked: 1
- Baldea I. Filip A. J. Physiol. Pharmacol. 2012 63 109 118 22653896
- Authors
- Zheng, Z., Liu, H., Zhai, S., Zhang, H., Shan, G., Kwok, R. T. K., Ma, C., Sung, H. H. Y., Williams, I. D., Lam, J. W. Y., Wong, K. S., Hu, X., & Tang, B. Z.
- Affiliations
- Hong Kong University of Science and Technology (HK)
- South China Normal University (CN)
- Department of Chemistry
- Corresponding author
- Hu, Xianglong
- Tang, Ben Zhong
- ORCID
- Venue
- Chemical Science
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2020
- Volume
- 11
- Issue
- 9
- Pages
- 2494-2503
- ISSN
- 2041-6520 (ISSN-L)
- 2041-6539
- PMC
- PMC8157451
- OpenAlex
- W3001223006
- Cited by
- 172
- References
- 63
- Citations by year
- 2026: 7 · 2025: 17 · 2024: 17 · 2023: 27 · 2022: 42 · 2021: 46 · 2020: 16
- FWCI
- 18.44
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Chemical Science (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Rare & Special e-Zone (The Hong Kong University of Science and Technology) (submittedVersion)
- Funders
- National Natural Science Foundation of China (21788102, 51973071, 21674040)
- University Grants Committee (AoE/P-03/08, AoE/P-02/12)
- Innovation and Technology Commission (ITC-CNERC14SC01, TCPD/17-9)
- National Basic Research Program of China (2018YFE0190200)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Photodynamic Therapy Research Studies
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Keywords
- singlet oxygen generation, two-photon photodynamic therapy, two-photon absorption, molecular engineering
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