Chemistries of bifunctional PROTAC degraders

Cao, Chaoguo, He, Ming, Wang, Liguo, He, Yuna, Rao, Yu·2022·Chemical Society Reviews

Cited by (315)

Items 301–315 of 315

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  7. BindingDB Entry 50021625: Discovery of Potent SOS1 PROTACs with Effective Antitumor Activities against NCI-H358 Tumor Cells In Vitro/In Vivo.
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  8. BindingDB Entry 50019870: Targeting Arginine Methyltransferase PRMT5 for Cancer Therapy: Updated Progress and Novel Strategies.
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  10. BindingDB Entry 50019737: Discovery of the First Potent, Selective, and
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  11. BindingDB Entry 50023634: Next-generation cancer therapeutics: PROTACs and the role of heterocyclic warheads in targeting resistance.
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  12. BindingDB Entry 50020095: Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2.
    BindingDB · 2024 · UC San Diego
  13. BindingDB Entry 50020617: Application of Novel Degraders Employing Autophagy for Expediting Medicinal Research.
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  14. Targeted protein degradation in cancer: strategies for undruggable targets and progress towards clinical translation
    Jinxin Tang, Zehao Cheng, Tian Xie, Yan Zhuang, Hongkun Hu, Chenbei Li, Hua Wang, Chengyao Feng, Chao Tu · 2026 · Biomarker Research
  15. Discovery of the First Orally Bioavailable GLI1 PROTAC for the Treatment of Colorectal Cancer
    Yabing Xin, Zi-Yu Yang, Yong-Fu Luo, Yan-Li Du, Rui-Ning Li, Qian Wu, Yangyang Chen, Xiang-Yang Li, Yixue Qiao, Mengchen Lu et al. · 2026 · European Journal of Medicinal Chemistry