Electrogelated drug-embedded silk/gelatin/rGO degradable electrode for anti-inflammatory applications in brain-implant systems
Abstract
A degradable electrogel drug-embedded silk/gelatin/rGO/DEX composite implanted electrode showed tunable mechanical properties and electro-stimulated drug release to interrupt astrocyte growth and reduce inflammatory response for utilization in neural interfaces.
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Cites
Tien, L. W., Wu, F., Tang‐Schomer, M. D., Yoon, E., Omenetto, F. G., & Kaplan, D. L. (2013) · Advanced Functional Materials · doi:10.1002/adfm.201203716 · Cited by 136 · see citing works
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- Authors
- Lin, Z.-K., Lin, J.-S., Chen, Z.-H., Cheng, H.-W., Huang, W.-C., & Chen, S.-Y.
- Affiliations
- National Yang Ming Chiao Tung University (TW)
- Corresponding author
- Cheng, Hung-Wei
- Huang, Wei-Chen
- Chen, San-Yuan
- Venue
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2024
- Volume
- 12
- Issue
- 5
- Pages
- 1361-1371
- ISSN
- 2050-750X (ISSN-L)
- 2050-7518
- OpenAlex
- W4390510207
- Cited by
- 7
- References
- 1
- Citations by year
- 2026: 3 · 2025: 4
- FWCI
- 1.22
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Materials Chemistry B (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science and Technology Council (MOST 111-2314-B-039-009-MY3)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Materials Science › Biomaterials › Silk-based biomaterials and applications
- Physical Sciences › Materials Science › Biomaterials › Electrospun Nanofibers in Biomedical Applications
- Keywords
- silk fibroin, gelatin, reduced graphene oxide, drug delivery, dexamethasone, anti-inflammatory response, neural implants, composite films
- MeSH terms
- Anti-Inflammatory Agents, Brain, Electrodes, Implanted, Gelatin, Humans, Inflammation, Silk
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