Cited by 1Structural and Chemical Analysis of Organic and Inorganic CompoundsAntifungal resistance and susceptibilitySynthesis and Characterization of Heterocyclic Compounds

Repurposing the phenylthiazole scaffold with 1,3,4-oxadiazole for selective, potent and well-tolerated antifungal activity

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Hagras, Mohamed, Ezzat, Hany G., Abuelkhir, Abdelrahman A., Mayhoub, Abdelrahman S.·2025·RSC Advances

Abstract

Invasive fungal infections (IFIs) represent a critical health threat, particularly among immunocompromised individuals, with mortality rates reaching up to 50%.

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Crossref · 10.1039/d5ra00499c

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Authors
Hagras, M., Ezzat, H. G., Abuelkhir, A. A., & Mayhoub, A. S.
Affiliations
Al-Azhar University (EG)
Corresponding author
Hagras, Mohamed
Venue
RSC Advances
Published
2025
Volume
15
Issue
12
Pages
9305-9319
ISSN
2046-2069 (ISSN-L)
OpenAlex
W4408910123
Cited by
1
References
1
Citations by year
2026: 1
FWCI
0.30
Type
journal article
Language
en
Open access
Locations
  • RSC Advances (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Chemistry › Organic Chemistry › Structural and Chemical Analysis of Organic and Inorganic Compounds
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Physical Sciences › Chemistry › Organic Chemistry › Synthesis and Characterization of Heterocyclic Compounds
Keywords
phenylthiazoles, 1,3,4-oxadiazoles, antifungal agents, invasive fungal infections, immunocompromised patients, drug selectivity

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