The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid
Open accessAbstract
A method is given for small-scale preparation of DNA from 1.0–1.5g of adult rat tissues. The product from brain or liver is characterized by base ratios and phosphorus content which accord with reported values for rat tissue. It is reasonably free of RNA, protein and glycogen. It contains 5-hydroxymethylcytosine at a content of about 15% of the total cytosine bases present. 5-Hydroxymethylcytosine is also demonstrable in mouse and frog brain DNA and in the crude cytidylic acid fractions obtained from RNA hydrolysates of rat brain and liver. 5-Hydroxymethylcytosine is identified by paper chromatography, u.v. spectra in acid and alkaline solutions and by its conversion into 5-hydroxymethyluracil.
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Citations
Cites
Detection of Sugars on Paper Chromatograms
TREVELYAN, W. E., PROCTER, D. P., & HARRISON, J. S. (1950) · Nature · doi:10.1038/166444b0 · Cited by 3,823
The purine and pyrimidine composition of deoxypentose nucleic acids
Wyatt, G. R. (1951) · Biochemical Journal · doi:10.1042/bj0480584 · Cited by 1,077
Wyatt, G. R., & Cohen, S. S. (1953) · Biochemical Journal · doi:10.1042/bj0550774 · Cited by 608
Markham, R., & Smith, J. (1949) · Biochemical Journal · doi:10.1042/bj0450294 · Cited by 540
Improved separation of sugars on the paper partition chromatogram
Jermyn, M. A., & Isherwood, F. A. (1949) · Biochemical Journal · doi:10.1042/bj0440402 · Cited by 460
Spectrophotometric studies op nucleic acid derivatives and related compounds as a function of pH
Shugar, D., & Fox, J. J. (1952) · Biochimica et Biophysica Acta · doi:10.1016/0006-3002(52)90147-9 · Cited by 426
THE LIPID COMPOSITION OF PURIFIED BOVINE BRAIN MYELIN*
NORTON, W. T., & AUTILIO, L. A. (1966) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1966.tb06794.x · Cited by 354
THE DETERMINATION OF DEOXYRIBONUCLEIC ACID AND OF CELL NUMBER IN BRAIN*
Zamenhof, S., Bursztyn-Pettegrew, H., RICH, K. C., & Zamenhof, P. J. (1964) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1964.tb07499.x · Cited by 133
Quantitative determination of deoxyribonucleic acid in rat brain
Penn, N. W., & SUWALSKI, R. T. (1969) · Biochemical Journal · doi:10.1042/bj1150563 · Cited by 9
Self-citation
Cited by
The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
Kriaucionis, S., & Heintz, N. (2009) · Science · doi:10.1126/science.1169786 · Cited by 2,700
Function and information content of DNA methylation
Schübeler, D. (2015) · Nature · doi:10.1038/nature14192 · Cited by 2,060
Global epigenomic reconfiguration during mammalian brain development
Lister, R., Mukamel, E. A., Nery, J. R., Urich, M., Puddifoot, C. A., Johnson, N. D., Lucero, J., Huang, Y., Dwork, A. J., Schultz, M. D., et al. (2013) · Science · doi:10.1126/science.1237905 · Cited by 1,830
TET enzymes, TDG and the dynamics of DNA demethylation
Kohli, R. M., & Zhang, Y. (2013) · Nature · doi:10.1038/nature12750 · Cited by 1,623
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
Pastor, W. A., Aravind, L., & Rao, A. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3589 · Cited by 897
Metadata
- Authors
- Penn, N. W., Suwalski, R., O'Riley, C., Bojanowski, K., & Yura, R.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1972-02-01
- Volume
- 126
- Issue
- 4
- Pages
- 781-790
- ISSN
- 0306-3283 (ISSN-L)
- OpenAlex
- W1521888731
- Cited by
- 280
- References
- 9
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Penn, N. W., Suwalski, R., O'Riley, C., Bojanowski, K., & Yura, R. (1972). The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid. Biochemical Journal. https://doi.org/10.1042/bj1260781
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
