The DOI matches its Crossref record; 2 of the 3 references it cites were found in a registry or an index.
The frequency of errors in protein biosynthesis
Open accessAbstract
Every protein molecule consists basically of a
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“Error frequencies of 0.01-0.1% per amino acid (AA) have been estimated for misincorporating structurally similar amino acids in vivo 20 .”
From How many human proteoforms are there? (2018) · cites this paper as [20]
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Citations
Cites
THE FREQUENCY OF ERRORS IN PROTEIN BIOSYNTHESIS
Loftfield, R. B. (1963) · Biochemical Journal · doi:10.1042/bj0890082 · Cited by 160
Self-citationHemoglobin Synthesis in Avian Erythrocytes
Hammel, C. L., & Bessman, S. P. (1964) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)82224-8 · Cited by 44
Cited by
Sorted by citations
Evolution of the mutation rate
Lynch, M. (2010) · Trends in Genetics · doi:10.1016/j.tig.2010.05.003 · Cited by 1,175
How many human proteoforms are there?
Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., et al. (2018) · Nature Chemical Biology · doi:10.1038/nchembio.2576 · Cited by 907
In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human Diseases
Hebert, D. N., & Molinari, M. (2007) · Physiological Reviews · doi:10.1152/physrev.00050.2006 · Cited by 704
Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration
Lee, J.-W., Beebe, K. D., Nangle, L. A., Jang, J.-S., Longo-Guess, C. M., Cook, S. A., Davisson, M. T., Sundberg, J. P., SCHIMMEL, P. R., & Ackerman, S. L. (2006) · Nature · doi:10.1038/nature05096 · Cited by 591
STRUCTURAL INSIGHTS INTO TRANSLATIONAL FIDELITY
Ogle, J. M., & Ramakrishnan, V. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.061903.155440 · Cited by 596
Metadata
- Authors
- Loftfield, R. B., & Vanderjagt, D.
- Affiliations
- University of New Mexico (US)
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1972-08-01
- Volume
- 128
- Issue
- 5
- Pages
- 1353-1356
- ISSN
- 0306-3283 (ISSN-L)
- PMC
- PMC1174024
- OpenAlex
- W1923250545
- Cited by
- 399
- References
- 3
- Citations by year
- 2026: 7 · 2025: 3 · 2024: 6 · 2023: 5 · 2022: 8 · 2021: 5 · 2020: 5 · 2019: 8 · 2018: 9 · 2017: 11 · 2016: 12 · 2015: 7 · 2014: 15 · 2013: 8 · 2012: 7
- FWCI
- 2.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Biochemical Journal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
- Keywords
- protein synthesis, error rate, translation errors, protein synthesis fidelity, aminoacyl-tRNA
- MeSH terms
- Amino Acid Sequence, Animals, DNA, Genetic Code, Hemoglobins, Hemoglobins, Abnormal, Humans, Rabbits, Reticulocytes, RNA, Transcription, Genetic, Protein Biosynthesis, In Vitro Techniques
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