Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation

Cited by (246)

Items 201–246 of 246

1. LINC00894 Regulates Cerebral Ischemia/Reperfusion Injury by Stabilizing EIF5 and Facilitating ATF4-Mediated Induction of FGF21 and ACOD1 Expression
   Yifei Chen, Hengxiang Cui, Zhuanzhuan Han, Lei Xu, Lin Wang, Yuefei Zhang, Lijun Liu · 2024 · Neurochemical Research
2. FGF21, not GCN2, influences bone morphology due to dietary protein restrictions
   Margaret A. McNulty, Brad A. Goupil, Diana C. Albarado, Teresa Castaño-Martínez, Thomas H. Ambrosi, Špela Puh, Tim Julius Schulz, Annette Schürmann, Christopher D. Morrison, Thomas Laeger · 2019 · Bone Reports
3. Pyruvate Upregulates Hepatic FGF21 Expression by Activating PDE and Inhibiting cAMP–Epac–CREB Signaling Pathway
   Yanyan Zhao, Lijun Zhang, Xiangyan Liang, Xiaochun Zhang, Jin-Rui Chang, Man Shi, Huan Liu, Ying Mei Zhou, Zhuo Sun, Yufeng Zhao · 2022 · International Journal of Molecular Sciences
4. Impact of moderate dietary protein restriction on glucose homeostasis in a model of estrogen deficiency
   Carole Fournier, Leonidas G. Karagounis, Sandra Maria Sacco, Marie-Noëlle Horcajada, Thomas Decaens, Elizabeth Offord, Karim Bouzakri, Patrick Ammann · 2022 · The Journal of Nutritional Biochemistry
5. Dietary BCAA supplementation counteracts the beneficial effects of long‐term aerobic exercise against obesity and associated metabolic disorders by suppressing FGF21 expression
   Jun Zhang, Xuejiao Zhang, Peiyuan Li, Yajin Liu, Chengnan Zhang, Mingyue Lu, Lei Gao, Zhenqiang Song, Haipeng Sun, Junqiang Qiu · 2025 · Diabetes Obesity and Metabolism
6. Systemic regulation of retinal medium-chain fatty acid oxidation repletes TCA cycle flux in oxygen-induced retinopathy
   Almut Heinken, John M. Asara, Gopalan Gnanaguru, Charandeep Singh · 2025 · Communications Biology
7. Growth hormone resistance induced by amino acid deprivation in fao cells is independent of FGF21
   Maki Saito, Hiroki Nishi, Shin‐Ichiro Takahashi, Fumihiko Hakuno, Ichiro Miyata · 2024 · Biochemical and Biophysical Research Communications
8. FGF21 and its Relationship with Inflammatory and Metabolic Parameters in HIV Patients after Antiretroviral Treatment
   Alan Joel Ruiz-Padilla, Yeniley Ruíz‐Noa, Lorena del Rocío Ibarra‐Reynoso, María-Luisa Lazo-de-la-Vega-Monroy, Ángel Josabad Alonso‐Castro, Mauricio Sánchez-Barajas, Rosa Margarita Alvarez-Alvarez, Mónica del Carmen Preciado‐Puga · 2020 · Current HIV Research
9. Possible effects of fibroblast growth factor 21 on vascular calcification via suppressing activating transcription factor 4 mediated apoptosis and osteogenic transformation in rats
   Yuchen Shi, Ze Zheng, Jesse Luo, Yingkai Li, Songyuan He, Xueqian Shen, Jinghua Liu · 2022 · Cell Biochemistry and Function
10. Nutrigenomics: Insights and Implications for Genome-Based Nutrition
    S. Rajesh, S. Varanavasiappan, Shunmugiah Veluchamy Ramesh · 2022 · Springer eBooks
11. A Polymorphism in the FGF21 Gene is a Novel Risk Variant for Metabolic-Associated Steatohepatitis
    Asmaa Elsayed · 2020 · The Sydney eScholarship Repository (The University of Sydney)
12. Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model
    Matthew W Gorton, Parniyan Goodarzi, Xia Lei, Michael C. Anderson, Mohammad Habibi, Nedra F. Wilson, Adel Pezeshki · 2025 · Nutrients
13. Deoxycholic acid derived from the gut microbiota involved in the regulation of adaptive thermogenesis in response to dietary protein restriction in plateau pika
    Fuyu Shi, Zhiteng Yang, Liangzhi Zhang, Desheng Zou, Jiangkun Yu, Na Guo, Shien Ren, Xianjiang Tang, Chen Juan Gu, Ruiping Xu et al. · 2025 · Microbiome
14. FGF21 reduces ER stress by enhancing the unfolded protein and integrated stress responses through increased sulfide signaling
    Gerald Grandl, Ann‐Christine König, Fabian Metzger, Arkadiusz Liśkiewicz, Tanja Hefele, Shelly Nason, Aaron Novikoff, Nada Al-Refaie, Md Abdur Rahman, Ahmed Khalil et al. · 2026 · Cell Metabolism
15. Fibroblast Growth Factor 21: Possible Role in Growth and Metabolic Development during Early Life, Nutritional Interactions and Biological Actions
    Jibran A. Wali, Jose M Ramos-Nieves, Aristea Binia, Eline M. van der Beek · 2026 · Advances in Nutrition
16. Lipid Response to Amino Acid Starvation in Fat Cells: Role of FGF21
    Albert Pérez‐Martí, Pedro F. Marrero, Diego Haro, Joana Relat · 2019 · Springer eBooks
17. α‐Lipoic acid up‐regulates gene expression but reduces protein levels of fibroblast growth factor 21 in HepG2 cells
    Xiaochun Zhang, Yanyan Zhao, Xiangyan Liang, Lijun Zhang, Ke Li, Zhuo Sun, Yufeng Zhao · 2022 · Basic & Clinical Pharmacology & Toxicology
18. Harnessing the Integrated Stress Response to Counteract Metabolic Disease
    Anne S. Henkel · 2018 · Hepatology
19. Systems levels analysis of lipid metabolism in oxygen-induced retinopathy
    Charandeep Singh · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
20. Metabolic signaling under nutrient deprivation
    De Sousa Coelho, Ana Luisa · 2012 · TDX (Tesis Doctorals en Xarxa)
21. Role of ATF4 in directing gene expression in the basal state and during the unfolded protein response in liver
    Michael E. Fusakio · 2016 · IUScholarWorks (Indiana University)
22. Molecular Nutrition Study of the Transcriptional Regulation of Anti-obesity Hormones
    Makoto Shimizu · 2016 · Nippon Eiyo Shokuryo Gakkaishi
23. Lipid Response to Amino Acid Starvation in Fat Cells: Role of FGF21
    Albert Pérez‐Martí, Pedro F. Marrero, Diego Haro, Joana Relat · 2017 · Springer eBooks
24. Fibroblast Growth Factor 21 is a Novel Protein Sensor in Pregnancy
    Elizabeth F. Sutton · 2017
25. Role of Fsp27 in lípid homeostasis during nutrient deprivation
    Alexandra Carrilho do Rosario · 2018 · Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona)
26. Signaling pathway and pharmacology
    Xiaokun Li · 2024 · Elsevier eBooks
27. The FGF metabolic axis
    Xiaokun Li · 2024 · Elsevier eBooks
28. Cardiokines and cardiac remodeling
    Asim K. Duttaroy, Rahul Mallick · 2024 · Elsevier eBooks
29. Immune infiltration and protective roles of FGF21 in liver injury, obesity, and hepatocellular cancer
    A. Olajuyin, C. Elferink, Casey W. Wright · 2025 · Discover medicine
30. A molecular tango between chromatin and metabolites orchestrates a feedback switch for alcohol consumption
    Heidi M. Schmidt, Elizabeth J. Tarling, Thomas Q. de Aguiar Vallim · 2025 · Proceedings of the National Academy of Sciences
31. Protein or Indispensable Amino Acid Supplementation After Deficiency Partially Restored Growth and Did Not Induce Higher Adiposity in Growing Rats
    Gaëtan Roisné-Hamelin, Céline Cansell, Catherine Chaumontet, Sarita Devi, Daniel Tomé, Anura V. Kurpad, Patrick C. Even, Anne Blais, Julien Piedcoq, Claire Gaudichon et al. · 2025 · Journal of Nutrition
32. Hepatocyte FGF21 is not required for fasting-induced metabolic responses but guides protein appetite after energy depletion
    Justine Bruse, Clothilde Marbach, Arnaud Polizzi, Tatiana Landré, Juliette Salvi, Valérie Alquier‐Bacquie, Chen Shiou-Ping, Marine Huillet, Clémence Rives, Céline M.P. Martin et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
33. Additional file 1 of SIRT1 regulates hepatic vldlr levels
    Mona Peyman, Anna Babin-Ebell Gonçalves, Rosalía Rodríguez‐Rodríguez, Matilde Rigon, David Aguilar-Recarte, Joan Villarroya, Anna Planavila, Villarroya, Francesc, Xavier Palomer, Emma Barroso et al. · 2024 · Figshare
34. Additional file 2 of Endoplasmic reticulum stress downregulates PGC-1α in skeletal muscle through ATF4 and an mTOR-mediated reduction of CRTC2
    Marta Montori-Grau, David Aguilar-Recarte, Mohammad Zarei, Javier Pizarro‐Delgado, Xavier Palomer, Vázquez-Carrera, Manuel · 2022 · Figshare
35. Additional file 3 of SIRT1 regulates hepatic vldlr levels
    Mona Peyman, Anna Babin-Ebell Gonçalves, Rosalía Rodríguez‐Rodríguez, Matilde Rigon, David Aguilar-Recarte, Joan Villarroya, Anna Planavila, Villarroya, Francesc, Xavier Palomer, Emma Barroso et al. · 2024 · Figshare
36. Additional file 2 of SIRT1 regulates hepatic vldlr levels
    Mona Peyman, Anna Babin-Ebell Gonçalves, Rosalía Rodríguez‐Rodríguez, Matilde Rigon, David Aguilar-Recarte, Joan Villarroya, Anna Planavila, Villarroya, Francesc, Xavier Palomer, Emma Barroso et al. · 2024 · Figshare
37. Additional file 4 of SIRT1 regulates hepatic vldlr levels
    Mona Peyman, Anna Babin-Ebell Gonçalves, Rodríguez-Rodríguez, Rosalía, Matilde Rigon, David Aguilar-Recarte, Joan Villarroya, Anna Planavila, Villarroya, Francesc, Xavier Palomer, Emma Barroso et al. · 2024 · Figshare
38. Osthole Activates FGF21 Expression by Mediating Activation of ATF4 in Human Hepatocyte HepG2 Cells
    Akishi Taguchi, Masaya Araki, Tomoya Yamashita, Ryo Kanazawa, Itsuki Terao, Kyohei Suzuki, Yuhei Tsuchimoto, Takashi Matsuzaka, Hirohito Sone, Hitoshi Shimano et al. · 2026 · International Journal of Molecular Sciences
39. Homéostasie des céramides et hépatopathies métaboliques
    Marion Régnier · 2018 · theses.fr (ABES)
40. Impact de la déficience en acides aminés indispensables sur le métabolisme protéique et énergétique, et identification de signatures métaboliques
    Joanna Moro · 2021 · theses.fr (ABES)
41. Influence du sexe dans la susceptibilité aux hépatopathies métaboliques
    Sarra Smati · 2019 · theses.fr (ABES)
42. Inter-organ communication in physiology and pathophysiology : a role for the ChREBP-FGF21 axis?
    Thaïs Carbinatti · 2024 · theses.fr (ABES)
43. Metabolic signatures of indispensable amino acids deficiencies : Identification and validation of urinary biomarkers
    Gaëtan Roisné-Hamelin · 2024 · theses.fr (ABES)
44. Hepatic FGF21 is not required for fasting metabolism but guides protein appetite post energy depletion
    Justine Bruse, Clothilde Marbach, Arnaud Polizzi, Tatiana Landré, Juliette Salvi, Valérie Alquier‐Bacquie, Shiou-Ping Chen, Marine Huillet, Clémence Rives, Martin Céline et al. · 2026 · EMBO Reports
45. Peptide hormone-based combinational pharmacotherapies for chronic metabolic diseases
    Zara Siu Wa Chui, Yaqian Xue, Xiaoping Wu, Aimin Xu · 2026 · Pharmacological Reviews
46. The GCN2-ATF4 Signaling Axis Orchestrates the Hepatic Transcriptional Stress Response to Short-term Sulfur Amino Acid Deprivation
    Valérie Carraro, Maelle Cherpaz, Lucie Longechamp, Cécile Coudy‐Gandilhon, Laurent Parry, Guillaume Voyard, Anne‐Catherine Maurin, Céline Jousse, Julien Avérous, Lydie Combaret et al. · 2026 · Journal of Molecular Biology