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Fat synthesis in adipose tissue. An examination of stoichiometric constraints
Open accessAbstract
The requirement for net balance of synthesis, degradation and transport for all intermediates in the pathways from glucose to fat imposes constraints on the balance of fluxes between different pathways. Linear programming has been used to examine the interactions between these constraints on metabolism in adipocytes and the requirement for efficiency in the conversion of glucose into fat. The circumstances under which excessive ATP synthesis would accompany this conversion have been investigated.
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Citations
Cited by
Genome-Scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network
Förster, J., Famili, I., Fu, P., Palsson, B. Ø., & Nielsen, J. (2003) · Genome Research · doi:10.1101/gr.234503 · Cited by 1,069
Varma, A., & Palsson, B. O. (1994) · Applied and Environmental Microbiology · doi:10.1128/aem.60.10.3724-3731.1994 · Cited by 1,051
Edwards, J. S., Ibarra, R. U., & Palsson, B. O. (2001) · Nature Biotechnology · doi:10.1038/84379 · Cited by 939
Constraining the metabolic genotype–phenotype relationship using a phylogeny of in silico methods
Lewis, N. E., Nagarajan, H., & Palsson, B. O. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2737 · Cited by 779
Metabolic modelling of microbes: the flux‐balance approach
Edwards, J. S., Covert, M., & Palsson, B. (2002) · Environmental Microbiology · doi:10.1046/j.1462-2920.2002.00282.x · Cited by 365
Metadata
- Authors
- Fell, D. A., & Small, J. R.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1986-09-15
- Volume
- 238
- Issue
- 3
- Pages
- 781-786
- ISSN
- 0264-6021 (ISSN-L)
- 1470-8728
- OpenAlex
- W2419380513
- Cited by
- 274
- References
- 0
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Fat synthesis in adipose tissue. An examination of stoichiometric constraints. https://app.cochat.ai/papers/10.1042/bj2380781
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- Fell, D. A., & Small, J. R. (1986). Fat synthesis in adipose tissue. An examination of stoichiometric constraints. Biochemical Journal. https://doi.org/10.1042/bj2380781
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.