The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Electrospray and tandem mass spectrometry in biochemistry
Open accessAbstract
Over the last 20 years, biological MS has changed out of all recognition. This is primarily due to the development in the 1980s of ‘soft ionization’ methods that permit the ionization and vaporization of large, polar, and thermally labile biomolecules. These developments in ionization mode have driven the design and manufacture of smaller and cheaper mass analysers, making the mass spectrometer a routine instrument in the biochemistry laboratory today. In the present review the revolutionary ‘soft ionization’ methods will be discussed with particular reference to electrospray. The mass analysis of ions will be described, and the concept of tandem MS introduced. Where appropriate, examples of the application of MS in biochemistry will be provided. Although the present review will concentrate on the MS of peptides/proteins and lipids, all classes of biomolecules can be analysed, and much excellent work has been done in the fields of carbohydrate and nucleic acid biochemistry.
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Citations
Cites
Electrospray Ionization for Mass Spectrometry of Large Biomolecules
Fenn, J. B., Mann, M., Meng, C. K., Wong, S. F., & Whitehouse, C. M. (1989) · Science · doi:10.1126/science.2675315 · Cited by 7,634
Cited by
Mass Spectrometry, Review of the Basics: Electrospray, MALDI, and Commonly Used Mass Analyzers
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Rafts: Scale‐Dependent, Active Lipid Organization at the Cell Surface
Mayor, S., & Rao, M. (2004) · Traffic · doi:10.1111/j.1600-0854.2004.00172.x · Cited by 379
Ambient mass spectrometry: bringing MS into the “real world”
Alberici, R. M., Simas, R. C., Sanvido, G. B., Romão, W., Lalli, P. M., Benassi, M., Cunha, I. B. S., & Eberlin, M. N. (2010) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-010-3808-3 · Cited by 340
Chace, D. H., Kalas, T. A., & Naylor, E. W. (2002) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.3.022502.103213 · Cited by 210
Bischel, H. N., MacManus-Spencer, L. A., Zhang, C., & Luthy, R. G. (2011) · Environmental Toxicology and Chemistry · doi:10.1002/etc.647 · Cited by 182
Metadata
- Authors
- GRIFFITHS, W. J., JONSSON, A. P., LIU, S., RAI, D. K., & WANG, Y.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 2001-04-24
- Volume
- 355
- Issue
- 3
- Pages
- 545-561
- ISSN
- 0264-6021 (ISSN-L)
- 1470-8728
- OpenAlex
- W1763558376
- Cited by
- 187
- References
- 1
- FWCI
- 8.31
- Type
- journal article
- Language
- en
- Open access
- bronze
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- GRIFFITHS, W. J., JONSSON, A. P., LIU, S., RAI, D. K., & WANG, Y. (2001). Electrospray and tandem mass spectrometry in biochemistry. Biochemical Journal. https://doi.org/10.1042/bj3550545
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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