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Cited by 388

The DOI matches its Crossref record; 127 of the 127 references it cites were found in a registry or an index.

Cell cycle checkpoints and their inactivation in human cancer

Open access
Molinari, M.·2000·Cell Proliferation

Abstract

Checkpoints are mechanisms that regulate progression through the cell cycle insuring that each step takes place only once and in the right sequence. Mutations of checkpoint proteins are frequent in all types of cancer as defects in cell cycle control can lead to genetic instability. This review will focus on three major areas of cell cycle transition control, with particular attention to the alterations found in human cancer. These areas include the G1/S transition, where most cancer‐related defects occur, the G2/M checkpoint and its activation in response to DNA damage, and the spindle checkpoint.

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Crossref · 10.1046/j.1365-2184.2000.00191.x

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Metadata

Authors
Molinari, M.
Venue
Cell Proliferation
Publisher
Wiley
Published
2000-10
Volume
33
Issue
5
Pages
261-274
ISSN
  • 0960-7722 (ISSN-L)
  • 1365-2184
OpenAlex
W2129695021
Cited by
388
References
127
FWCI
3.11
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Cell cycle checkpoints and their inactivation in human cancer. https://app.cochat.ai/papers/10.1046/j.1365-2184.2000.00191.x
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Molinari, M. (2000). Cell cycle checkpoints and their inactivation in human cancer. Cell Proliferation. https://doi.org/10.1046/j.1365-2184.2000.00191.x

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.