The influence of gender on the short and long‐term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5‐year study

Drake, W. M.; Rodríguez‐Arnao, J.; Weaver, J. U.; James, I. T.; Coyte, D.; Spector, T. D.; Besser, G. M.; Monson, J. P.

doi:10.1046/j.1365-2265.2001.01246.x

The influence of gender on the short and long‐term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5‐year study

OBJECTIVES The objectives of this study were to investigate the effects of GH replacement therapy in hypopituitary adults with growth hormone deficiency (GHD) on activation of bone remodelling during dose titration and on BMD over a median of 58 months of continuous therapy. STUDY DESIGN Open lab…