Requirement of Runx1/AML1/PEBP2αB for the generation of haematopoietic cells from endothelial cells

Recent studies revealing that endothelial cells derived from E8.5‐E10.5 mouse embryos give rise to haematopoietic cells appear to correspond to previous histological observations that haematopoietic cell clusters are attached to the ventral aspect of dorsal aorta in such a way as if they were bud…