The Yfe system of Yersinia pestis transports iron and manganese and is required for full virulence of plague

Iron acquisition in Yersinia pestis is fundamental to the success of plague pathogenesis. We have previously identified an ≈5.6 kb region ( yfe ) of Y. pestis genomic DNA, capable of restoring iron‐deficient growth but not siderophore production to an Escherichia coli mutant (SAB11) incapable of …