The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4
Abstract
Summary: Salicylic acid (SA) is an important regulator of plant defense responses, and a variety of Arabidopsis mutants impaired in resistance against bacterial and fungal pathogens show defects in SA accumulation, perception, or signal transduction. Nevertheless, the role of SA‐dependent defense responses against necrotrophic fungi is currently unclear. We determined the susceptibility of a set of previously identified Arabidopsis mutants impaired in defense responses to the necrotrophic fungal pathogen Botrytis cinerea. The rate of development of B. cinerea disease symptoms on primary infected leaves was affected by responses mediated by the genes EIN2, JAR1, EDS4, PAD2, and PAD3, but was largely independent of EDS5, SID2/ICS1, and PAD4. Furthermore, plants expressing a nahG transgene or treated with a phenylalanine ammonia lyase (PAL) inhibitor showed enhanced symptoms, suggesting that SA synthesized via PAL, and not via isochorismate synthase (ICS), mediates lesion development. In addition, the degree of lesion development did not correlate with defensin or PR1 expression, although it was partially dependent upon camalexin accumulation. Although npr1 mutant leaves were normally susceptible to B. cinerea infection, a double ein2 npr1 mutant was significantly more susceptible than ein2 plants, and exogenous application of SA decreased B. cinerea lesion size through an NPR1‐dependent mechanism that could be mimicked by the cpr1 mutation. These data indicate that local resistance to B. cinerea requires ethylene‐, jasmonate‐, and SA‐mediated signaling, that the SA affecting this resistance does not require ICS1 and is likely synthesized via PAL, and that camalexin limits lesion development.
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Cites
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Self-citationRequirement of Salicylic Acid for the Induction of Systemic Acquired Resistance
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Cited by
Arabidopsis WRKY33 transcription factor is required for resistance to necrotrophic fungal pathogens
Zheng, Z., Qamar, S. A., Chen, Z., & Mengiste, T. (2006) · The Plant Journal · doi:10.1111/j.1365-313x.2006.02901.x · Cited by 988
Plant pathogenesis-related (PR) proteins: A focus on PR peptides
Sels, J., Mathys, J., De Coninck, B. M. A., Cammue, B. P. A., & De Bolle, M. F. C. (2008) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2008.06.011 · Cited by 836
Mengiste, T. (2012) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-081211-172955 · Cited by 566
Mengiste, T., Chen, X., Salmeron, J., & Dietrich, R. (2003) · The Plant Cell · doi:10.1105/tpc.014167 · Cited by 553
The Role of Ethylene in Host-Pathogen Interactions
Broekaert, W. F., Delauré, S. L., De Bolle, M. F. C., & Cammue, B. P. A. (2006) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.44.070505.143440 · Cited by 503
Metadata
- Authors
- Ferrari, S., Plotnikova, J. M., De Lorenzo, G., & Ausubel, F. M.
- Venue
- The Plant Journal
- Publisher
- Wiley
- Published
- 2003-06-23
- Volume
- 35
- Issue
- 2
- Pages
- 193-205
- ISSN
- 0960-7412 (ISSN-L)
- 1365-313X
- OpenAlex
- W1884528635
- Cited by
- 532
- References
- 42
- FWCI
- 20.65
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ferrari, S., Plotnikova, J. M., De Lorenzo, G., & Ausubel, F. M. (2003). Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4. The Plant Journal. https://doi.org/10.1046/j.1365-313x.2003.01794.x
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