CoChat
Sign Up
Cited by 151Obstructive Sleep Apnea ResearchHeart Rate Variability and Autonomic ControlCardiac electrophysiology and arrhythmias

The DOI matches its Crossref record; 26 of the 27 references it cites were found in a registry or an index.

Relationship Among the Severity of Sleep Apnea Syndrome, Cardiac Arrhythmias, and Autonomic Imbalance

ROCHE, FRÉDÉRIC, THANH XUONG, ALAIN NGUYEN, COURT‐FORTUNE, ISABELLE, COSTES, FRÉDÉRIC, PICHOT, VINCENT, DUVERNEY, DAVID, VERGNON, JEAN‐MICHEL, GASPOZ, JEAN‐MICHEL, BARTHÉLÉMY, JEAN‐CLAUDE·2003·Pacing and Clinical Electrophysiology
DOI 10.1046/j.1460-9592.2003.00116.x
Open this paper in CoChat — free account

Abstract

The relationship between obstructive sleep apnea syndrome (OSAS), cardiac arrhythmias, and conduction disturbances in adults remains controversial. Early studies showed a higher prevalence than more recent and designed epidemiological studies. To clarify the actual prevalence of cardiac arrhythmias and conduction disturbances in patients referred for assessment of OSAS, a prospective cohort study was conducted: 147 consecutive patients (103 men; mean age of 54.5 +/- 10.7 years) underwent time-synchronized polysomnography and ECG Holter monitoring. OSAS was diagnosed in 66 (44.9%) of them based on an apnea hypopnea index (AHI) > or = 10. Prevalence of heart failure, of prior myocardial infarction, of hypertension, and of ventricular arrhythmias were similar in patients with or without OSAS. Nocturnal paroxysmal asystole was significantly more prevalent in OSAS patients (10.6 vs 1.2%; P < 0.02) and the number of episodes of bradycardia and pauses increased with the severity of the syndrome. Almost all bradycardic events occurred in patients with severe OSAS (AHI > 30), prolonged periods of arterial oxyhemoglobin desaturation, and low diurnal awake PaO2. Moreover, using heart rate variability analysis, nocturnal sinusal dysfunction contrasted with a blunted diurnal parasympathetic modulation of the sinus node. Frequent nocturnal nonsustained supraventricular tachycardias were predominantly found in patients with severe sleep related breathing disorders; however, an increased risk of ventricular arrhythmias was not found. Under continuous positive airway pressure treatment, the 1-year follow-up of OSAS patients with nocturnal pauses did not reveal any arrhythmic event justifying a specific intervention.

Overview

Integrity signals

Registry

Crossref · 10.1046/j.1460-9592.2003.00116.x

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 27 references

Research works printed but not linked: 6

  1. Lazarus A, 1993, Arythmies et syndrome d’apnées obstructives du sommeil de l’adulte, Arch Mal Cœur, 86, 1753
  2. Le Heuzey JY, 1989, Enregistrement Holter et syndrome d’apnée du sommeil, Cœur, 20, 195
  3. Tilkian AG, 1978, Sleep Apnea Syndromes, 197
  4. Quanjer P., 1983, Standardization of lung function tests, Bull Eur Physiopath Resp, 19, 1
  5. Rechtschaffen A., 1968, A Manual of Standardized Terminology, Techniques and Scoring Systems for Sleep Stages of Human Subjects
  6. Thorpy M, 1990, Committee ftDCS. The International Classification of Sleep Disorders: Diagnostic and Coding Manuel

Cited by

Sorted by citations

Items 101–150 of 150

Related

See all

Metadata

Authors
ROCHE, F., THANH XUONG, A. N., COURT‐FORTUNE, I., COSTES, F., PICHOT, V., DUVERNEY, D., VERGNON, J., GASPOZ, J., & BARTHÉLÉMY, J.
Affiliations
  • Université Jean Monnet (FR)
  • University Hospital of Geneva (CH)
Corresponding author
ROCHE, FRÉDÉRIC
ORCID
Venue
Pacing and Clinical Electrophysiology
Publisher
Wiley
Published
2003-03
Volume
26
Issue
3
Pages
669-677
ISSN
  • 0147-8389 (ISSN-L)
  • 1540-8159
DOI
10.1046/j.1460-9592.2003.00116.x
OpenAlex
W1986316647
Cited by
151
References
27
Citations by year
2026: 2 · 2025: 2 · 2024: 5 · 2023: 3 · 2022: 7 · 2021: 5 · 2020: 7 · 2019: 3 · 2018: 6 · 2017: 8 · 2016: 12 · 2015: 4 · 2014: 9 · 2013: 7 · 2012: 10
FWCI
2.97
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 31 d)
Locations
  • Pacing and Clinical Electrophysiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords
obstructive sleep apnea, cardiac arrhythmias, autonomic imbalance, bradycardia, cardiac conduction disorders, heart rate variability, sick sinus syndrome, supraventricular tachycardia, ventricular arrhythmias, apnea-hypopnea index, continuous positive airway pressure, nocturnal hypoxemia
MeSH terms
Arrhythmias, Cardiac, Autonomic Nervous System Diseases, Female, Follow-Up Studies, Heart Conduction System, Humans, Male, Middle Aged, Prospective Studies, Time Factors, Electrocardiography, Ambulatory, Prevalence, Polysomnography, Sleep Apnea, Obstructive

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review