Cited by 299Migraine and Headache StudiesHealth Systems, Economic Evaluations, Quality of LifeHealth Education and Validation

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Validity and Reliability of the Migraine‐Specific Quality of Life Questionnaire (MSQ Version 2.1)

Martin, Bradley C., Pathak, Dev S., Sharfman, Marc I., Adelman, James U., Taylor, Frederick, Kwong, W. Jackie, Jhingran, Priti·2000·Headache: The Journal of Head and Face Pain

DOI 10.1046/j.1526-4610.2000.00030.x

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Abstract

Objective.–To assess the scaling properties, reliability, and validity of the revised Migraine‐Specific Quality of Life Questionnaire (MSQ) (Version 2.1) Background.–The MSQ is a disease‐specific, quality‐of‐life instrument with three hypothesized scales that has been developed, tested, and revised. Methods.–The study used a multicenter, nondrug, prospective, parallel group, quasi‐experimental design. Patients with migraine were recruited at outpatient headache specialty practices and were administered the MSQ, the Medical Outcomes Study 36‐Item Short Form Health Survey (SF‐36), and migraine symptom questionnaires at baseline, 4 weeks, and 12 weeks. Internal consistency (Cronbach α) and 4‐week test‐retest reproducibility (intraclass correlation coefficients) were estimated to assess reliability. Construct validity was assessed using an adaptation of the Campbell and Fiske multitrait‐multimethod approach and by correlating MSQ scores with symptom measures. Results.–A total of 267 subjects enrolled in the trial. The criteria for summated rating scales were all met. The internal consistency coefficients ranged from 0.86 to 0.96, and the intraclass correlation coefficients ranged from 0.57 to 0.63 across the three dimensions. As anticipated, the MSQ dimensions had low‐to‐modest correlations with the two component scores of the SF‐36 and were modestly to moderately correlated with migraine symptoms. Conclusions.–The MSQ is a reliable instrument in the assessment of quality of life for patients with migraine with items that can be summed without weights. The MSQ has demonstrated evidence of construct validity.

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Additional file 3 of Long-term treatment with lasmiditan in patients with migraine: post hoc analysis of treatment patterns and outcomes from the open-label extension of the CENTURION randomized trial
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Additional file 5 of Real-life use of onabotulinumtoxinA reduces healthcare resource utilization in individuals with chronic migraine: the REPOSE study
Kollewe, K., Gaul, C., Gendolla, A., & Sommer, K. (2021) · Figshare · doi:10.6084/m9.figshare.14721741
Additional file 1 of L-arginine and aged garlic extract for the prevention of migraine: a study protocol for a randomised, double-blind, placebo-controlled, phase-II trial (LARGE trial)
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Additional file 4 of Real-life use of onabotulinumtoxinA reduces healthcare resource utilization in individuals with chronic migraine: the REPOSE study
Kollewe, K., Gaul, C., Gendolla, A., & Sommer, K. (2021) · Figshare · doi:10.6084/m9.figshare.14721738
Additional file 1 of Long-term treatment with lasmiditan in patients with migraine: post hoc analysis of treatment patterns and outcomes from the open-label extension of the CENTURION randomized trial
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Additional file 2 of Efficacy of mindfulness added to treatment as usual in patients with chronic migraine and medication overuse headache: a phase-III single-blind randomized-controlled trial (the MIND-CM study)
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Souza, M. N. P., Владимирович, С. К., Puledda, F., Messina, R., Lee, M. J., Hassan, A., Schytz, H. W., Ashina, S., Gelfand, A. A., & Goadsby, P. J. (2026) · Cephalalgia Reports · doi:10.1177/25158163261486759
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Migraine Headache: A family affair.
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Determinants of Health Related Quality of Life among Adolescents with Migraine
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Authors: Martin, B. C., Pathak, D. S., Sharfman, M. I., Adelman, J. U., Taylor, F., Kwong, W. J., & Jhingran, P.
Affiliations: University of Georgia (US)
The Ohio State University (US)
Headache Wellness Center (US)
Park Nicollet Health Services (US)
ORCID: Martin, Bradley C.
Pathak, Dev S.
Taylor, Frederick
Venue: Headache: The Journal of Head and Face Pain
Publisher: Wiley
Published: 2000-03-27
Volume: 40
Issue: 3
Pages: 204-216
ISSN: 0017-8748 (ISSN-L)
1526-4610
DOI: 10.1046/j.1526-4610.2000.00030.x
OpenAlex: W1968001773
Cited by: 299
References: 30
Citations by year: 2026: 14 · 2025: 26 · 2024: 32 · 2023: 27 · 2022: 18 · 2021: 34 · 2020: 17 · 2019: 10 · 2018: 8 · 2017: 7 · 2016: 7 · 2015: 4 · 2014: 6 · 2013: 6 · 2012: 11
FWCI: 4.42
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor, 638 d)
Locations: Headache The Journal of Head and Face Pain (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Health Sciences › Nursing › Research and Theory › Health Education and Validation
Keywords: Migraine-Specific Quality of Life Questionnaire, migraine, quality of life, psychometric validation, construct validity, reliability statistics, internal consistency, test-retest reproducibility, SF-36, migraine symptoms, disease-specific questionnaire
MeSH terms: Evaluation Studies as Topic, Humans, Migraine Disorders, Prospective Studies, Quality of Life, Surveys and Questionnaires, Reproducibility of Results

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Validity and Reliability of the Migraine‐Specific Quality of Life Questionnaire (MSQ Version 2.1)

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