The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Cerebral Activation during Vagus Nerve Stimulation: A Functional MR Study
Abstract
Summary: Purpose: To study the short‐term effects of vagus nerve stimulation (VNS) on brain activation and cerebral blood flow by using functional magnetic resonance imaging (fMRI). Methods: Five patients (three women, two men; mean age, 35.4 years) who were treated for medically refractory epilepsy with VNS, underwent fMRI. All patients had a nonfocal brain MRI. The VNS was set at 30 Hz, 0.5–2.0 mA for intervals of activation of 30 s on and 30 s off, during which the fMRI was performed. Statistical parametric mapping (SPM) was used to determine significant areas of activation or inhibition during vagal nerve stimulation (p < 0.05). Results: VNS‐induced activation was detected in the thalami bilaterally (left more than right), insular cortices bilaterally, ipsilateral basal ganglia and postcentral gyri, right posterior superior temporal gyrus, and inferomedial occipital gyri (left more than right). The most robust activation was seen in the thalami (left more than right) and insular cortices. Conclusions: VNS‐induced thalamic and insular cortical activation during fMRI suggests that these areas may play a role in modulating cerebral cortical activity, and the observed decrease in seizure frequency in patients who are given VNS may be a consequence of this increased activation.
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Natural waking and sleep states: a view from inside neocortical neurons
Steriade, M., Timofeev, I., & Grenier, F. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.5.1969 · Cited by 1,296
Sleep and arousal: thalamocortical mechanisms
McCormick, D. A., & Bal, T. (1997) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.20.1.185 · Cited by 1,267
Cited by
Forebrain emotional asymmetry: a neuroanatomical basis?
Craig, A. D. (. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.10.005 · Cited by 626
Optimization of Transcutaneous Vagus Nerve Stimulation Using Functional MRI
Yakunina, N., Kim, S. S., & Nam, E.-C. (2017) · Neuromodulation: Technology at the Neural Interface · doi:10.1111/ner.12541 · Cited by 494
Kraus, T., Hösl, K., Kiess, O., Schanze, A., Kornhuber, J., & Forster, C. (2007) · Journal of Neural Transmission · doi:10.1007/s00702-007-0755-z · Cited by 408
Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII)
Bialer, M., Johannessen, S. I., Kupferberg, H. J., Levy, R. H., Perucca, E., & Tomson, T. (2004) · Epilepsy Research · doi:10.1016/j.eplepsyres.2004.07.010 · Cited by 300
Interoception, homeostatic emotions and sympathovagal balance
Strigo, I. A., & Craig, A. D. (. (2016) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2016.0010 · Cited by 281
Metadata
- Authors
- Narayanan, J. T., Watts, R., Haddad, N., Labar, D. R., Li, P. M., & Filippi, C. G.
- Venue
- Epilepsia
- Publisher
- Wiley
- Published
- 2002-12
- Volume
- 43
- Issue
- 12
- Pages
- 1509-1514
- ISSN
- 0013-9580 (ISSN-L)
- 1528-1167
- OpenAlex
- W2009420340
- Cited by
- 159
- References
- 3
- FWCI
- 4.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- Narayanan, J. T., Watts, R., Haddad, N., Labar, D. R., Li, P. M., & Filippi, C. G. (2002). Cerebral Activation during Vagus Nerve Stimulation: A Functional MR Study. Epilepsia. https://doi.org/10.1046/j.1528-1157.2002.16102.x
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