Review on enhancing clinical decision support system using machine learning
Open accessAbstract
Clinical decision‐making is a complex patient‐centred process. For an informed clinical decision, the input data is very thorough ranging from detailed family history, environmental history, social history, health‐risk assessments, and prior relevant medical cases. Identifying the need for structured input data to enable clinical decision‐making and quality reporting, such that it is crucial for the end‐users is still a challenge. The Clinical Decision Support Systems (CDSS) enhanced using Machine Learning (ML) approaches are described. CDSS aids in the detection and classification of various diseases but they cannot fully capture the environmental, clinical, and social constraints that are taken into consideration by the clinician in the diagnosis process. The authors provide an overview of state‐of‐the‐art healthcare CDSS. The authors initially collected 3165 research articles for this review out of which approximately 3148 records were identified from databases while 17 records were from other sources. A total of 1309 unique articles obtained from the searches were included in the study which was further rigorously evaluated for final inclusion. A generic architecture of computer‐based decision support systems using ML is provided. However, the study does not include the comparison of these CDSS in terms of their performance because of heterogeneity in the disease type, modality used for diagnosis, and the ML approach used for detection in CDSS.
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By integrating and analyzing patient symptoms, medical history, test results, and other risk factors, CDSS have the capability to support disease detection and identification.
“By integrating and analyzing patient symptoms, medical history, test results, and other risk factors, CDSS have the capability to support disease detection and identification [214,215], such as the subtle or ambiguous patterns that clinicians often overlook [216,217].”
From Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors (2026) · cites this paper as [215]
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Clinical decision support in the era of artificial intelligence
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Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors
Yen, C., Epling, J. W., Rockwell, M., & Vaughn-Cooke, M. (2026) · Diagnostics · doi:10.3390/diagnostics16020347 · Cited by 6 · see citing works
- Authors
- Masood, A., Naseem, U., Rashid, J., Kim, J., & Razzak, I.
- Affiliations
- Boston Children's Hospital (US)
- Macquarie University (AU)
- Sejong University (KR)
- Kongju National University (KR)
- UNSW Sydney (AU)
- Corresponding author
- Rashid, Junaid
- Kim, Jungeun
- Venue
- CAAI Transactions on Intelligence Technology
- Published
- 2024-02-06
- ISSN
- 2468-2322 (ISSN-L)
- 2468-6557
- OpenAlex
- W4391611262
- Cited by
- 14
- References
- 6
- Citations by year
- 2026: 9 · 2025: 4 · 2024: 1
- FWCI
- 4.27
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- CAAI Transactions on Intelligence Technology (publishedVersion, cc-by)
- Figshare (submittedVersion, cc-by)
- Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- Topics
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Keywords
- clinical decision support systems, machine learning in healthcare, disease detection, disease classification, clinical decision-making, patient-centered care, structured clinical data
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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