Cited by 19Colorectal Cancer Screening and DetectionAI in cancer detectionArtificial Intelligence in Healthcare and Education

Strengths and weaknesses of an artificial intelligence polyp detection program as assessed by a high-detecting endoscopist

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Rex, Douglas K., Mori, Yuichi, Sharma, Prateek, Lahr, Rachel E., Vemulapalli, Krishna C., Hassan, Cesare·2022·Gastroenterology

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Crossref · 10.1053/j.gastro.2022.03.055

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  • AI performance in lesion detection has been reported as similar to the best human experts.

    “Overall, AI performance in lesion detection has been reported as similar to the best human experts [41 , 42] .”

    From Enhancing human-AI collaboration: The case of colonoscopy (2024) · cites this paper as [42]

    The Statistical Analysis table (page unavailable) reports 671 lesions detected simultaneously by AI and a high-detecting endoscopist, supporting some similarity in detection. But the Conclusions (page unavailable) say AI missed some larger flat lesions and remained an adjunct to expert detection; the paper does not establish that its overall detection performance matches the best human experts. (LLM, conf=0.82)

    Experimental — accuracy not yet measured
  • Available AI devices exhibit very high sensitivity and overall performance on par with or better than top human experts.

    “Available AI devices exhibit very high sensitivity and overall performance on par with or better than top human experts [42 , 76] .”

    From Enhancing human-AI collaboration: The case of colonoscopy (2024) · cites this paper as [42]

    The Testing section reports that the CADe device increased adenoma detection for a high-detecting endoscopist, supporting a performance benefit. But the paper does not establish very high sensitivity or performance on par with or better than top experts across available devices: it assessed one device, reports lesions the device missed, and notes that some endoscopists without AI have exceeded detection rates achieved in AI trials. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

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Research works printed but not linked: 16

  1. Rex DK, Boland CR, Dominitz JA, et al. Colorectal cancer screening: recommendations for physicians and patients from the U.S. Multi- Society Task Force on Colorectal Cancer. Gastrointest Endosc 2017; 86:18-33.
  2. Shaukat A, Rector TS, Church TR, et al. Longer withdrawal time is associated with a reduced inci- dence of interval cancer after screening colonoscopy. Gastroen- terology 2015;149:952-957.
  3. Kaminski MF, Wieszczy P, Rupinski M, et al. Increased rate of adenoma detection associates with reduced risk of colorectal cancer and death. Gastroenterology 2017; 153:98-105.
  4. Rex DK. If surgeons embrace ade- noma detection rate measurement and improvement, cancers will be prevented and lives will be saved. Dis Colon Rectum 2020; 63:867-869.
  5. Wang P, Berzin TM, Glissen Brown JR, et al. Real-time auto- matic detection system increases colonoscopic polyp and adenoma detection rates: a prospective randomised controlled study. Gut 2019;68:1813-1819.
  6. Su JR, Li Z, Shao XJ, et al. Impact of a real-time automatic quality control system on colorectal polyp and adenoma detection: a pro- spective randomized controlled study (with videos). Gastrointest Endosc 2020;91:415-424.e4.
  7. Repici A, Badalamenti M, Maselli R, et al. Efficacy of real-time com- puter-aided detection of colorectal neoplasia in a randomized trial. Gastroenterology 2020; 159:512-520.e7.
  8. Wang P, Liu X, Berzin TM, et al. Effect of a deep-learning com- puter-aided detection system on adenoma detection during colo- noscopy (CADe-DB trial): a double- blind randomised study. Lancet Gastroenterol Hepatol 2020; 5:343-351.
  9. Wallace MB, Sharma P, Bhandari P, et al. Impact of artificial intelligence on miss rates of colo- rectal neoplasia. Gastroenterology 2022;163:295-304.
  10. Hassan C, Wallace MB, Sharma P, et al. New artificial intelligence system: first validation study versus experienced endoscopists for colorectal polyp detection. Gut 2020;69:799-800.
  11. Yao L, Zhang L, Liu J, et al. Effect of an artificial intelligence-based quality improvement system on efficacy of a computer-aided detection system in colonoscopy: a four-group parallel study [pub- lished online ahead of print November 25, 2021]. Endoscopy https://doi.org/10.1055/a-1706- 6174. · DOI · Paper page
  12. Rex DK, Repici A, Gross SA, et al. High-definition colonoscopy versus Endocuff versus EndoRings versus full-spectrum endoscopy for ade- noma detection at colonoscopy: a multicenter randomized trial. Gas- trointest Endosc 2018;88:335-344. e2-e16.
  13. Lafeuille P, Yzet C, Rivory J, et al. Flat colorectal adenocarcinoma: a worrisome false negative of artifi- cial intelligence-assisted colonos- copy [published online ahead of print February 15, 2022]. Endos- copy https://doi.org/10.1055/a- 1738-9632. · DOI
  14. Yamada M, Saito Y, Imaoka H, et al. Development of a real-time endoscopic image diagnosis sup- port system using deep learning technology in colonoscopy. Sci Rep 2019;9:14465.
  15. Kamba S, Tamai N, Saitoh I, et al. Reducing adenoma miss rate of colonoscopy assisted by artificial intelligence: a multicenter random- ized controlled trial. J Gastroenterol 2021;56:746-757.
  16. Hassan C, Spadaccini M, Iannone A, et al. Performance of artificial intelligence in colonoscopy for adenoma and polyp detection: a systematic review and meta-anal- ysis. Gastrointest Endosc 2021; 93:77-85.e6.

Cited by

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Authors
Rex, D. K., Mori, Y., Sharma, P., Lahr, R. E., Vemulapalli, K. C., & Hassan, C.
Affiliations
  • Indiana University School of Medicine (US)
  • University of Oslo (NO)
  • University of Kansas (US)
  • Humanitas University (IT)
Venue
Gastroenterology
Publisher
Elsevier BV
Published
2022-08
Volume
163
Issue
2
Pages
354-358.e1
ISSN
0016-5085 (ISSN-L)
OpenAlex
W4223516062
Cited by
19
References
3
Citations by year
2026: 1 · 2025: 7 · 2024: 5 · 2023: 5 · 2022: 1
FWCI
1.88
Type
journal article
Language
en
Open access
Locations
  • Gastroenterology (publishedVersion)
  • PubMed (publishedVersion)
  • IUScholarWorks (Indiana University) (submittedVersion)
  • Purdue University Indianapolis (Indiana University) (submittedVersion)
Funders
  • Horizon 2020 Framework Programme (101026196)
  • Medtronic
  • Braintree Laboratories
  • Boston Scientific Corporation
  • Aries Pharmaceuticals
  • EndoAid
  • European Commission
  • Olympus
  • Covidien
Topics
  • Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
  • Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
Keywords
artificial intelligence, polyp detection, colonoscopy, adenoma detection rate, colorectal cancer screening, operator dependence, AI performance evaluation, colorectal adenoma, interval cancer, withdrawal time, colorectal cancer prevention, endoscopy training, AI-assisted endoscopy, colorectal cancer risk stratification, colorectal cancer screening guidelines, colorectal cancer risk
MeSH terms
Artificial Intelligence, Colonic Polyps, Colonoscopy, Humans

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