Early Primary Repair of Tetralogy of Fallot
Abstract
Outcomes for surgical repair of tetralogy of Fallot with pulmonary stenosis are often considered to be a useful benchmark for the assessment of congenital surgical programs. This procedure, including preoperative assessment and postoperative management, falls in the middle of the spectrum of difficulty of all the congenital cardiac procedures. Within this anomaly itself, there is a wide spectrum of severity and difficulty. However, it is important to distinguish tetralogy with pulmonary stenosis or "simple tetralogy" from the much more complex anomaly tetralogy of Fallot with pulmonary atresia. Tetralogy of Fallot with pulmonary stenosis is virtually always operable. It is also a progressive condition that is therefore best repaired in early infancy following echocardiographic diagnosis alone.
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The mortality rate is higher than rates reported in high-volume centers with early interventions.
“Despite the low morbidity, mortality was recorded in five patients (11.6%), which is higher than rates reported in high-volume centers with early interventions [15–16].”
From Management of tetralogy of fallot in developing countries: opportunities and challenges for surgeons (2026) · cites this paper as [16]
Single-center studies from Pakistan and Tanzania reported mortality rates of 1.3-9% for late repairs, with higher rates generally associated with poorer preoperative condition and lower institutional capacity.
“Single-center studies from Pakistan and Tanzania reported mortality rates of 1.3–9% for late repairs, with higher rates generally associated with poorer preoperative condition and lower institutional capacity [15–16].”
From Management of tetralogy of fallot in developing countries: opportunities and challenges for surgeons (2026) · cites this paper as [16]
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References 23 · Cited by 70
- Authors
- Jonas, R. A.
- Affiliations
- Children's National (US)
- Corresponding author
- Jonas, Richard A.
- ORCID
- Jonas, Richard A.
- Venue
- Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual
- Publisher
- Elsevier BV
- Published
- 2009
- Volume
- 12
- Issue
- 1
- Pages
- 39-47
- ISSN
- 1092-9126 (ISSN-L)
- OpenAlex
- W2006873331
- Cited by
- 70
- References
- 23
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 4 · 2023: 3 · 2022: 3 · 2021: 4 · 2020: 6 · 2019: 4 · 2018: 7 · 2017: 2 · 2016: 2 · 2015: 5 · 2014: 6 · 2013: 9 · 2012: 3
- FWCI
- 2.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery Annual (publishedVersion)
- PubMed (publishedVersion)
- Seminars in Thoracic and Cardiovascular Surgery
- Topics
- Health Sciences › Medicine › Epidemiology › Congenital Heart Disease Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiovascular Conditions and Treatments
- Keywords
- tetralogy of Fallot, pulmonary stenosis, infancy, congenital heart surgery, surgical outcomes, preoperative assessment, postoperative care, tetralogy of Fallot with pulmonary atresia, echocardiographic diagnosis
- MeSH terms
- Cardiac Surgical Procedures, Humans, Infant, Infant, Newborn, Pulmonary Valve Stenosis, Tetralogy of Fallot
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